Reaction Details



 Reaction ID 88
 Stochiometric Equation 5,10-Methylenetetrahydrofolate + dUMP <-> dTMP + Dihydrofolate
 Substrates
dUMP
5,10-Methylenetetrahydrofolate
 Products
dTMP
Dihydrofolate
 Enzymes known to
 catalyse this reaction
 (curated information)
EC Number in Organism UniProtKB Link PubMedID
2.1.1.45 Bacillus subtilis UniProtKB 418407
2.1.1.45 Bacteriophage T4 UniProtKB 2271601
2.1.1.45 Crithidia fasciculata UniProtKB 14696
2.1.1.45 Escherichia coli UniProtKB 10704192
2.1.1.45 Escherichia coli UniProtKB 10841779
2.1.1.45 Escherichia coli UniProtKB 14967040
2.1.1.45 Escherichia coli UniProtKB 26612036
2.1.1.45 Escherichia coli UniProtKB 3286637
2.1.1.45 Homo sapiens UniProtKB 12859954
2.1.1.45 Homo sapiens UniProtKB 2656695
2.1.1.45 Homo sapiens UniProtKB 269853
2.1.1.45 Homo sapiens UniProtKB 34155
2.1.1.45 Lactobacillus casei UniProtKB 10704192
2.1.1.45 Lactobacillus casei UniProtKB 10964985
2.1.1.45 Lactobacillus casei UniProtKB 1284431
2.1.1.45 Lactobacillus casei UniProtKB 1606134
2.1.1.45 Lactobacillus casei UniProtKB 1627545
2.1.1.45 Lactobacillus casei UniProtKB 2153960
2.1.1.45 Lactobacillus casei UniProtKB 2182628
2.1.1.45 Lactobacillus casei UniProtKB 413834
2.1.1.45 Lactobacillus casei UniProtKB 8180187
2.1.1.45 Lactobacillus casei UniProtKB 8378336
2.1.1.45 Lactobacillus casei UniProtKB 9383465
2.1.1.45 Lactobacillus casei UniProtKB 9398324
2.1.1.45 Leishmania major UniProtKB 3597407
2.1.1.45 Leishmania major UniProtKB 8144647
2.1.1.45 Leishmania tropica UniProtKB 3922404
2.1.1.45 Rattus norvegicus UniProtKB 3567221
2.1.1.45 Toxoplasma gondii UniProtKB 12192007
2.1.1.45 Trypanosoma cruzi UniProtKB 14696
2.1.1.45 Trypanosoma cruzi UniProtKB 7969266
 Pathways Folate biosynthesis
One carbon pool by folate
Pyrimidine metabolism
 External Links
 KEGG-Pathway-ID map00790
map00670
map00240
 KEGG-Reaction-ID R02101
 MetaNetX-Reaction-ID MNXR104889
 Rhea-Reaction-ID 12106 12107 12104 12105


View all entries for reaction 5,10-Methylenetetrahydrofolate + dUMP <-> dTMP + Dihydrofolate

© HITS gGmbH