Pathway Details

 Recommended name One carbon pool by folate
 Alternative names
 Reactions
2 NADP+ + 5,6,7,8-Tetrahydrofolate <-> 2 H+ + 2 NADPH + Folate
L-Glutamate + 5-Formiminotetrahydrofolate <-> 5,6,7,8-Tetrahydrofolate + N-Formimino-L-glutamate
5,10-Methylenetetrahydrofolate + dUMP <-> dTMP + Dihydrofolate
NAD+ + 5-Methyltetrahydrofolate <-> NADH + H+ + 5,10-Methylenetetrahydrofolate
5,6,7,8-Tetrahydrofolate + S-Aminomethyldihydrolipoylprotein <-> NH3 + 5,10-Methylenetetrahydrofolate + Dihydrolipoylprotein
Glycine + 5-Formiminotetrahydrofolate <-> 5,6,7,8-Tetrahydrofolate + N-Formiminoglycine
5,10-Methylenetetrahydrofolate + FADH2 <-> FAD + 5-Methyltetrahydrofolate
10-Formyltetrahydrofolate + L-Methionyl-tRNA(Met) <-> 5,6,7,8-Tetrahydrofolate + N-Formylmethionyl-tRNA(fMet)
L-Glutamate + 5-Formyltetrahydrofolate <-> 5,6,7,8-Tetrahydrofolate + N-Formyl-L-glutamate
NADP+ + 5-Methyltetrahydrofolate <-> H+ + NADPH + 5,10-Methylenetetrahydrofolate
NAD+ + 5,6,7,8-Tetrahydrofolate <-> NADH + H+ + Dihydrofolate
5-Formyltetrahydrofolate <-> H2O + 5,10-Methenyltetrahydrofolate
H2O + 5,10-Methenyltetrahydrofolate <-> H+ + 10-Formyltetrahydrofolate
L-Homocysteine + 5-Methyltetrahydrofolate <-> L-Methionine + 5,6,7,8-Tetrahydrofolate
H2O + 5,10-Methenyltetrahydrofolate + 5'-Phosphoribosylglycinamide <-> 5,6,7,8-Tetrahydrofolate + 5'-Phosphoribosyl-N-formylglycinamide
H2O + NADP+ + 10-Formyltetrahydrofolate <-> H+ + NADPH + CO2 + 5,6,7,8-Tetrahydrofolate
5-Formiminotetrahydrofolate <-> NH3 + 5,10-Methenyltetrahydrofolate
NAD+ + 5,10-Methylenetetrahydrofolate <-> NADH + H+ + 5,10-Methenyltetrahydrofolate
NADP+ + 5,10-Methylenetetrahydrofolate <-> H+ + NADPH + 5,10-Methenyltetrahydrofolate
5,6,7,8-Tetrahydrofolate + Trimethylsulfonium <-> 5-Methyltetrahydrofolate + Dimethyl sulfide
5,6,7,8-Tetrahydrofolate + One carbon pool <-> 10-Formyltetrahydrofolate
NADP+ + Dihydrofolate <-> H+ + NADPH + Folate
5,10-Methylenetetrahydrofolate + 2 Reduced ferredoxin <-> 2 Oxidized ferredoxin + 5-Methyltetrahydrofolate
NADP+ + 5,6,7,8-Tetrahydrofolate <-> H+ + NADPH + Dihydrofolate
ATP + 5-Formyltetrahydrofolate <-> ADP + Phosphate + 5,10-Methenyltetrahydrofolate
ADP + Phosphate + 10-Formyltetrahydrofolate <-> ATP + H2O + 5-Formyltetrahydrofolate
NAD+ + 5,6,7,8-Tetrahydrofolate <-> NADH + H+ + Folate
H2O + dCMP + 5,10-Methylenetetrahydrofolate <-> 5,6,7,8-Tetrahydrofolate + 2'-Deoxy-5-hydroxymethylcytidine 5'-phosphate
H2O + 10-Formyltetrahydrofolate <-> Formate + 5,6,7,8-Tetrahydrofolate
H2O + Glycine + 5,10-Methylenetetrahydrofolate <-> L-Serine + 5,6,7,8-Tetrahydrofolate
H2O + 5,10-Methylenetetrahydrofolate + D-Alanine <-> 5,6,7,8-Tetrahydrofolate + 2-Methylserine
10-Formyltetrahydrofolate + 5'-Phosphoribosylglycinamide <-> 5,6,7,8-Tetrahydrofolate + 5'-Phosphoribosyl-N-formylglycinamide
NAD+ + Dihydrofolate <-> NADH + H+ + Folate
ATP + Formate + 5,6,7,8-Tetrahydrofolate <-> ADP + Phosphate + 10-Formyltetrahydrofolate
5,10-Methylenetetrahydrofolate + dUMP + FADH2 <-> dTMP + FAD + 5,6,7,8-Tetrahydrofolate
10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <-> 5,6,7,8-Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
 Classification
Metabolism of Cofactors and Vitamins
© HITS gGmbH