Pathway Details

 Recommended name Pyrimidine metabolism
 Alternative names
 Reactions
H2O + Uracil + Acceptor <-> Barbiturate + Reduced acceptor
5,10-Methylenetetrahydrofolate + dUMP <-> dTMP + Dihydrofolate
Phosphate + Thymidine <-> Thymine + 2-Deoxy-D-ribose 1-phosphate
H2O + Trimetaphosphate <-> Triphosphate
NADP+ + 5,6-Dihydrothymine <-> H+ + Thymine + NADPH
ATP + Pseudouridine <-> ADP + Pseudouridine 5'-phosphate
ATP + H2O + UTP + L-gamma-Glutamyl hydrazide <-> ADP + Phosphate + L-Glutamate + N4-Amino-CTP
H2O + N-Carbamoyl-beta-alanine <-> CO2 + NH3 + beta-Alanine
ATP + 2'-Deoxycytidine <-> ADP + dCMP
H2O + L-Dihydroorotate <-> N-Carbamoyl-L-aspartate
ITP + Uridine <-> IDP + UMP
ATP + Cytidine <-> ADP + CMP
ATP + UTP + Hydrazine <-> ADP + Phosphate + N4-Amino-CTP
H2O + Oxidized thioredoxin + dUTP <-> UTP + Reduced thioredoxin
Cytidine + dTTP <-> CMP + dTDP
ATP + Zalcitabine <-> ADP + L-ddCMP
dCTP + DNA <-> Diphosphate + DNA
H2O + dCMP + 5,10-Methylenetetrahydrofolate <-> 5,6,7,8-Tetrahydrofolate + 2'-Deoxy-5-hydroxymethylcytidine 5'-phosphate
H2O + 2'-Deoxycytidine <-> NH3 + 2'-Deoxyuridine
H2O + UDP-D-glucose <-> alpha-D-Glucose 1-phosphate + UMP
H2O + dUTP <-> Diphosphate + dUMP
Uridine + dUTP <-> UMP + dUDP
NAD+ + 5,6-Dihydrouracil <-> NADH + H+ + Uracil
H2O + Cytidine <-> Cytosine + D-Ribose
Diphosphate + Orotidine 5'-phosphate <-> 5-Phospho-alpha-D-ribose 1-diphosphate + Orotate
H2O + dCDP <-> Phosphate + dCMP
ITP + Cytidine <-> CMP + IDP
Uracil + Acceptor <-> Barbiturate + Reduced acceptor
Phosphate + Uridine <-> Uracil + D-Ribose 1-phosphate
Thymidine + Base <-> Thymine + 2-Deoxy-D-ribosyl-base
H2O + dCMP <-> Phosphate + 2'-Deoxycytidine
Diphosphate + UMP <-> Uracil + 5-Phospho-alpha-D-ribose 1-diphosphate
H2O + 5,6-Dihydrothymine <-> 3-Ureidoisobutyrate
ATP + UTP + Hydroxylamine <-> ADP + Phosphate + N4-Hydroxyl-CTP
Phosphate + Cytidine <-> Cytosine + D-Ribose 1-phosphate
H2O + Uridine <-> Uracil + D-Ribose
Cytidine + dGTP <-> CMP + dGDP
Phosphate + RNA <-> CDP + RNA
H2O + P1,P4-Bis(5'-uridyl) tetraphosphate <-> UTP + UMP
ATP + dCMP <-> ADP + dCDP
ATP + dTDP <-> ADP + dTTP
NAD+ + L-Dihydroorotate <-> NADH + H+ + Orotate
Uridine + dTTP <-> UMP + dTDP
H2O + CTP <-> Phosphate + CDP
H2O + CDP <-> Phosphate + CMP
H2O + dTTP <-> Phosphate + dTDP
H2O + L-gamma-Glutamyl hydrazide <-> L-Glutamate + Hydrazine
Carbamoyl phosphate <-> Cyclic amidines
H+ + NADPH + 5,10-Methylenetetrahydrofolate + dUMP <-> dTMP + NADP+ + 5,6,7,8-Tetrahydrofolate
UTP + Cytidine <-> UDP + CMP
H2O + dTDP <-> Phosphate + dTMP
Phosphate + RNA <-> UDP + RNA
NADP+ + 5,6-Dihydrouracil <-> H+ + Uracil + NADPH
ATP + 2'-Deoxyuridine <-> ADP + dUMP
H2O + Cytidine <-> NH3 + Uridine
AMP + UTP <-> ADP + UDP
Cytidine + dCTP <-> CMP + dCDP
H2O + dUTP <-> Phosphate + dUDP
Uridine + dCTP <-> UMP + dCDP
ATP + CDP <-> ADP + CTP
ATP + dCDP <-> ADP + dCTP
H2O + 5-Methylbarbiturate <-> Urea + Methylmalonate
H2O + dTMP <-> Phosphate + Thymidine
H2O + L-6-Thiodihydroorotate <-> N-Carbamoyl-L-aspartate
ATP + H2O + L-Glutamine + UTP <-> ADP + Phosphate + L-Glutamate + CTP
ATP + dUDP <-> ADP + dUTP
Phosphate + 2'-Deoxyuridine <-> Uracil + 2-Deoxy-D-ribose 1-phosphate
H2O + UMP <-> Phosphate + Uridine
H2O + Oxidized thioredoxin + dCTP <-> CTP + Reduced thioredoxin
Phosphate + Uridine <-> Uracil + alpha-D-Ribose 1-phosphate
H2O + Uridine 3'-phosphate <-> Phosphate + Uridine
Cytidine + dUTP <-> CMP + dUDP
ATP + Cytarabine <-> ADP + 1-beta-D-Arabinofuranosylcytosine 5'-monophosphate
H2O + dCMP <-> NH3 + dUMP
ATP + CMP <-> ADP + CDP
H2O + L-Glutamine <-> L-Glutamate + NH3
ATP + UDP <-> ADP + UTP
CTP + RNA <-> Diphosphate + RNA
H2O + UTP <-> Diphosphate + UMP
H2O + Oxidized thioredoxin + dUDP <-> UDP + Reduced thioredoxin
H2O + 2',3'-Cyclic UMP <-> Uridine 3'-phosphate
H2O + CMP <-> Cytosine + D-Ribose 5-phosphate
H2O + 2',3'-Cyclic CMP <-> Cytidine 3'-phosphate
NAD+ + 5,6-Dihydrothymine <-> NADH + H+ + Thymine
H2O + Cytosine <-> Uracil + NH3
2 H2O + dCTP <-> Diphosphate + NH3 + dUMP
ATP + H2O + UTP + L-gamma-Glutamyl hydroxamate <-> ADP + Phosphate + L-Glutamate + N4-Hydroxyl-CTP
ATP + Thymidine <-> ADP + dTMP
Orotidine 5'-phosphate <-> CO2 + UMP
UTP + Uridine <-> UDP + UMP
ATP + NH3 + UTP <-> ADP + Phosphate + CTP
H2O + 5,6-Dihydrouracil <-> N-Carbamoyl-beta-alanine
H2O + L-gamma-Glutamyl hydroxamate <-> L-Glutamate + Hydroxylamine
Phosphate + 5-Fluorouridine <-> D-Ribose 1-phosphate + 5-FU
ATP + Uridine <-> ADP + UMP
H2O + UDPglucose <-> UMP + D-Glucose 1-phosphate
Phosphate + Cytidine <-> Cytosine + alpha-D-Ribose 1-phosphate
H2O + Cytidine 3'-phosphate <-> Phosphate + Cytidine
L-Aspartate + Carbamoyl phosphate <-> Phosphate + N-Carbamoyl-L-aspartate
H2O + UTP <-> Phosphate + UDP
O2 + L-Dihydroorotate <-> H2O2 + Orotate
H2O + Oxidized thioredoxin + dCDP <-> CDP + Reduced thioredoxin
H2O + CTP <-> Diphosphate + CMP
2 H2O + Barbiturate <-> Urea + Malonate
ADP + 2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate <-> ATP + 2'-Deoxy-5-hydroxymethylcytidine 5'-phosphate
GTP + Cytidine <-> GDP + CMP
H2O + 3-Ureidoisobutyrate <-> CO2 + NH3 + 3-Aminoisobutanoate
Uracil + D-Ribose 5-phosphate <-> H2O + Pseudouridine 5'-phosphate
H2O + Thymine + Acceptor <-> 5-Methylbarbiturate + Reduced acceptor
Phosphate + Doxifluridine <-> 5-FU + 5-Deoxy-D-ribose 1-phosphate
H2O + CTP <-> NH3 + UTP
H2O + dCTP <-> dCMP + Diphosphate
NADP+ + Reduced thioredoxin <-> H+ + NADPH + Oxidized thioredoxin
H2O + CMP <-> Phosphate + Cytidine
Uridine + dGTP <-> UMP + dGDP
ATP + UMP <-> ADP + UDP
dATP + Cytidine <-> CMP + dADP
dATP + Uridine <-> UMP + dADP
Ubiquinone + L-Dihydroorotate 6'-methylester <-> Ubiquinol + Orotate 6'-methylester
H2O + UDP <-> Phosphate + UMP
dTTP + DNA <-> Diphosphate + DNA
CDP + Reduced glutaredoxin <-> H2O + dCDP + Oxidized glutaredoxin
2 ATP + H2O + L-Glutamine + Hydrogencarbonate <-> 2 ADP + Phosphate + L-Glutamate + Carbamoyl phosphate
ATP + dUMP <-> ADP + dUDP
ATP + dTMP <-> ADP + dTDP
H2O + 5-Methylcytosine <-> Thymine + NH3
5,10-Methylenetetrahydrofolate + dUMP + FADH2 <-> dTMP + FAD + 5,6,7,8-Tetrahydrofolate
H2O + dCTP <-> NH3 + dUTP
ATP + 2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate <-> ADP + 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate
H2O + dUMP <-> Phosphate + 2'-Deoxyuridine
Phosphate + 5-Fluorodeoxyuridine <-> 2-Deoxy-D-ribose 1-phosphate + 5-FU
UTP + RNA <-> Diphosphate + RNA
GTP + Uridine <-> GDP + UMP
 Classification
Nucleotide Metabolism
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