Reaction Details



 Reaction ID 8593
 Stochiometric Equation L-Tryptophan + O2 + Tetrahydrobiopterin <-> 5-Hydroxy-L-tryptophan + 4a-Hydroxytetrahydrobiopterin
 Substrates
O2
Tetrahydrobiopterin
L-Tryptophan
 Products
5-Hydroxy-L-tryptophan
4a-Hydroxytetrahydrobiopterin
 Enzymes known to
 catalyse this reaction
 (curated information)
EC Number in Organism UniProtKB Link PubMedID
1.14.16.1 Homo sapiens UniProtKB 9434741
1.14.16.1 Rattus norvegicus UniProtKB 7407194
1.14.16.4 Homo sapiens UniProtKB 16581181
1.14.16.4 Homo sapiens UniProtKB 17181551
1.14.16.4 Homo sapiens UniProtKB 17539919
1.14.16.4 Homo sapiens UniProtKB 17905754
1.14.16.4 Homo sapiens UniProtKB 17973628
1.14.16.4 Homo sapiens UniProtKB 19816759
 Pathways Folate biosynthesis
Metabolic pathways
Phenylalanine metabolism
 External Links
 KEGG-Pathway-ID map00790
map01100
map00360
 KEGG-Reaction-ID R07213
 MetaNetX-Reaction-ID MNXR152455


View all entries for reaction L-Tryptophan + O2 + Tetrahydrobiopterin <-> 5-Hydroxy-L-tryptophan + 4a-Hydroxytetrahydrobiopterin

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