Pathway Details

 Recommended name Phenylalanine metabolism
 Alternative names
 Reactions
NAD+ + Coenzyme A + Acetaldehyde <-> NADH + H+ + Acetyl-CoA
ATP + H2O + L-Phenylalanine <-> Diphosphate + AMP + D-Phenylalanine
NAD+ + H2O + L-Phenylalanine <-> NADH + H+ + NH3 + Phenylpyruvate
H2O + L-Phenylalanine + O2 <-> NH3 + H2O2 + Phenylpyruvate
L-Phenylalanine + O2 <-> H2O + CO2 + 2-Phenylacetamide
Pyruvate + L-Phenylalanine <-> L-Alanine + Phenylpyruvate
L-Phenylalanine + Acetyl-CoA <-> Coenzyme A + N-Acetyl-L-phenylalanine
L-Phenylalanine + 2-Oxoglutarate <-> L-Glutamate + Phenylpyruvate
L-Phenylalanine <-> NH3 + trans-Cinnamate
L-Phenylalanine <-> 2-Phenylacetamide
L-Phenylalanine <-> CO2 + 2-Phenylethylamine
Pyruvate + Acetaldehyde <-> 4-Hydroxy-2-oxopentanoate
Acetyl-CoA + Succinyl-CoA <-> Coenzyme A + 3-Oxoadipyl-CoA
NADH + H+ + Acetate + 4-Hydroxybenzoate <-> NAD+ + 2 H2O + 4-Coumarate
NAD+ + Phenyllactate <-> NADH + H+ + Phenylpyruvate
NADP+ + Phenyllactate <-> H+ + NADPH + Phenylpyruvate
O2 + Phenylpyruvate <-> CO2 + 2-Hydroxyphenylacetate
H2O + D-Phenylalanine <-> NH3 + Phenylpyruvate
Phenylpyruvate <-> CO2 + Phenylacetaldehyde
Phenylpyruvate <-> Enol-Phenylpyruvate
H2O + Hippurate <-> Glycine + Benzoate
NADH + H+ + Acetate + Benzoate <-> NAD+ + 2 H2O + trans-Cinnamate
Benzoate <-> 3-Hydroxybenzoate
2-Oxoglutarate + D-Phenylalanine <-> Phenylpyruvate + D-Glutamate
ATP + Coenzyme A + 4-Coumarate <-> Diphosphate + AMP + 4-Coumaroyl-CoA
L-Phenylalanine + O2 + Tetrahydrobiopterin <-> H2O + L-Tyrosine + 6,7-Dihydrobiopterin
L-Tryptophan + O2 + Tetrahydrobiopterin <-> H2O + 6,7-Dihydrobiopterin + 5-Hydroxy-L-tryptophan
S-Adenosyl-L-methionine + Caffeoyl-CoA <-> S-Adenosyl-L-homocysteine + Feruloyl-CoA
NAD+ + Phenylpropanoate <-> NADH + H+ + trans-Cinnamate
H+ + NADPH + O2 + trans-Cinnamate <-> H2O + NADP+ + 4-Coumarate
H+ + NADPH + O2 + trans-Cinnamate <-> H2O + NADP+ + 2-Coumarate
NAD+ + Coenzyme A + alpha-Oxo-benzeneacetic acid <-> NADH + H+ + CO2 + Benzoyl-CoA
Glycine + Benzoyl-CoA <-> Coenzyme A + Hippurate
NAD+ + H2O + Phenylacetaldehyde <-> NADH + H+ + Phenylacetic acid
H2O + NADP+ + Phenylacetaldehyde <-> H+ + NADPH + Phenylacetic acid
ATP + Coenzyme A + Phenylacetic acid <-> Diphosphate + AMP + Phenylacetyl-CoA
H2O + 2-Phenylacetamide <-> NH3 + Phenylacetic acid
L-Glutamine + Phenylacetyl-CoA <-> Coenzyme A + alpha-N-Phenylacetyl-L-glutamine
H2O + 2-Hydroxy-2,4-pentadienoate <-> 4-Hydroxy-2-oxopentanoate
Succinate + 2-Hydroxy-2,4-pentadienoate <-> H2O + 2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate
NAD+ + Phenylethyl alcohol <-> NADH + H+ + Phenylacetaldehyde
H2O + 2-Phenylethylamine + Acceptor <-> NH3 + Phenylacetaldehyde + Reduced acceptor
H2O + O2 + 2-Phenylethylamine <-> NH3 + H2O2 + Phenylacetaldehyde
NADH + H+ + O2 + 3-(2-Hydroxyphenyl)propanoate <-> NAD+ + H2O + 3-(2,3-Dihydroxyphenyl)propanoate
NAD+ + Ephedrine <-> NADH + H+ + (R)-2-Methylimino-1-phenylpropan-1-ol
NAD+ + 3-(2-Hydroxyphenyl)propanoate <-> NADH + H+ + 2-Coumarate
Acetyl-CoA + D-Phenylalanine <-> Coenzyme A + N-Acetyl-D-phenylalanine
O2 + 3-(2,3-Dihydroxyphenyl)propanoate <-> 2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate
3-(2-Hydroxyphenyl)propanoate <-> Phenylpropanoate
2-Hydroxyphenylacetate <-> 2,6-Dihydroxyphenylacetate
H2O + Feruloyl-CoA <-> 4-Hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA
4-Hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA <-> Acetyl-CoA + 4-Hydroxy-3-methoxy-benzaldehyde
Glycine + Phenylacetyl-CoA <-> Coenzyme A + Phenylacetylglycine
Phenylpropanoate <-> 3-(3-Hydroxy-phenyl)-propanoic acid
trans-Cinnamate <-> trans-3-Hydroxycinnamate
NADH + H+ + O2 + Phenylpropanoate <-> NAD+ + cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol
NADH + H+ + O2 + trans-Cinnamate <-> NAD+ + cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol
NAD+ + cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol <-> NADH + H+ + 3-(2,3-Dihydroxyphenyl)propanoate
NAD+ + cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol <-> NADH + H+ + trans-2,3-Dihydroxycinnamate
NADH + H+ + O2 + 3-(3-Hydroxy-phenyl)-propanoic acid <-> NAD+ + H2O + 3-(2,3-Dihydroxyphenyl)propanoate
NADH + H+ + O2 + trans-3-Hydroxycinnamate <-> NAD+ + H2O + trans-2,3-Dihydroxycinnamate
O2 + trans-2,3-Dihydroxycinnamate <-> 2-Hydroxy-6-ketononatrienedioate
H2O + 2-Hydroxy-6-ketononatrienedioate <-> Fumarate + 2-Hydroxy-2,4-pentadienoate
Phenylacetic acid <-> 4-Hydroxyphenylacetate
Phenylacetic acid <-> 3-Hydroxyphenylacetate
Riboflavin-5-phosphate + Phenyllactate <-> Phenylpyruvate + Reduced FMN
Riboflavin-5-phosphate + Indolelactate <-> Reduced FMN + Indolepyruvate
Riboflavin-5-phosphate + 2-Hydroxyisocaproate <-> 4-Methyl-2-oxopentanoate + Reduced FMN
H2O + O2 + 4-Methoxyphenylethylamine <-> NH3 + H2O2 + 4-Methoxyphenylacetaldehyde
NAD+ + (3S)-3-Hydroxyadipyl-CoA <-> NADH + H+ + 3-Oxoadipyl-CoA
H2O + 5-Carboxy-2-pentenoyl-CoA <-> (3S)-3-Hydroxyadipyl-CoA
O2 + Phenyllactate <-> H2O2 + Phenylpyruvate
L-Phenylalanine + O2 + Tetrahydrobiopterin <-> L-Tyrosine + 4a-Hydroxytetrahydrobiopterin
L-Tryptophan + O2 + Tetrahydrobiopterin <-> 5-Hydroxy-L-tryptophan + 4a-Hydroxytetrahydrobiopterin
H+ + NADPH + O2 + trans-Cinnamate <-> H2O + NADP+ + 2-Hydroxycinnamate
H2O + Phenylglyoxylyl-CoA <-> Coenzyme A + alpha-Oxo-benzeneacetic acid
H2O + D-Phenylalanine + Acceptor <-> NH3 + Phenylpyruvate + Reduced acceptor
H2O + Phenylacetyl-CoA <-> Coenzyme A + Phenylacetic acid
 Classification
Amino Acid Metabolism
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