Reaction Details



 Reaction ID 7840
 Stochiometric Equation H+ + NADPH + 5,10-Methylenetetrahydrofolate + dUMP <-> dTMP + NADP+ + 5,6,7,8-Tetrahydrofolate
 Substrates
dUMP
H+
5,10-Methylenetetrahydrofolate
NADPH
 Products
dTMP
5,6,7,8-Tetrahydrofolate
NADP+
 Enzymes known to
 catalyse this reaction
 (curated information)
EC Number in Organism UniProtKB Link PubMedID
2.1.1.148 Chlamydia trachomatis UniProtKB 15591067
2.1.1.148 Thermotoga maritima UniProtKB 15301527
Complex: 1.5.1.3 / 2.1.1.45 Leishmania major UniProtKB 12556445
Complex: 1.5.1.3 / 2.1.1.45 Toxoplasma gondii UniProtKB 12556445
 Pathways Pyrimidine metabolism
 External Links
 KEGG-Pathway-ID map00240
 KEGG-Reaction-ID R06613
 MetaNetX-Reaction-ID MNXR104890
 Rhea-Reaction-ID 29045 29046 29043 29044


View all entries for reaction H+ + NADPH + 5,10-Methylenetetrahydrofolate + dUMP <-> dTMP + NADP+ + 5,6,7,8-Tetrahydrofolate

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