Reaction Details



 Reaction ID 122
 Stochiometric Equation 10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <-> 5,6,7,8-Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
 Substrates
10-Formyltetrahydrofolate
1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
 Products
5,6,7,8-Tetrahydrofolate
1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
 Enzymes known to
 catalyse this reaction
 (curated information)
EC Number in Organism UniProtKB Link PubMedID
2.1.2.3 Gallus gallus UniProtKB 1937050
2.1.2.3 Homo sapiens UniProtKB 14966129
 Pathways Biosynthesis of secondary metabolites
Metabolic pathways
One carbon pool by folate
Purine metabolism
 External Links
 KEGG-Pathway-ID map01110
map01100
map00670
map00230
 KEGG-Reaction-ID R04560
 MetaNetX-Reaction-ID MNXR95639
 Rhea-Reaction-ID 22192 22193 22194 22195
 Reactome-Reaction-ID R-DME-73798 R-HSA-73798 R-XTR-73798 R-BTA-73798 R-SSC-73798 R-CFA-73798 R-RNO-73798 R-OSA-73798 R-TGU-73798 R-DDI-73798 R-GGA-419254 R-SPO-73798 R-SCE-73798 R-ATH-73798 R-DRE-73798 R-GGA-73798 R-MMU-73798


View all entries for reaction 10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <-> 5,6,7,8-Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide

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