Pathway Details

 Recommended name Purine metabolism
 Alternative names
 Reactions
ATP + H2O + L-Glutamine + 5'-Phosphoribosyl-N-formylglycinamide <-> ADP + Phosphate + L-Glutamate + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
H2O + IMP <-> Phosphate + Inosine
H2O + Adenosine-5'-phosphoimidazolide <-> AMP + Imidazole
H2O + Inosine <-> Hypoxanthine + D-Ribose
ATP + Adenosine <-> ADP + AMP
NAD+ + H2O + Hypoxanthine <-> NADH + H+ + Xanthine
Phosphate + Deoxyinosine <-> Hypoxanthine + 2-Deoxy-D-ribose 1-phosphate
H2O + dGTP <-> Triphosphate + Deoxyguanosine
alpha-D-Ribose 1-phosphate <-> alpha-D-Ribose 5-phosphate
Phosphate + Xanthosine <-> D-Ribose 1-phosphate + Xanthine
H2O + GTP <-> Phosphate + GDP
H2O + ITP <-> Phosphate + IDP
ATP + GMP <-> ADP + GDP
ATP + AMP <-> 2 ADP
H2O + Xanthine <-> 5-Ureido-4-imidazole carboxylate
Ureidoglycolate <-> Urea + Glyoxylate
Phosphate + Deoxyguanosine <-> Guanine + 2-Deoxy-D-ribose 1-phosphate
H2O + Adenosine 3'-phosphate <-> Phosphate + Adenosine
H2O + O2 + Xanthine <-> Urate + H2O2
H2O + AMP <-> Phosphate + Adenosine
Glycine + 5-Formiminotetrahydrofolate <-> 5,6,7,8-Tetrahydrofolate + N-Formiminoglycine
H2O + Adenosine <-> NH3 + Inosine
ATP + L-Aspartate + 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate <-> ADP + Phosphate + 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
ATP + dIDP <-> ADP + dITP
ATP + ADP <-> Phosphate + P1,P4-Bis(5'-adenosyl) tetraphosphate
H2O + Guanine <-> NH3 + Xanthine
H2O + Xanthosine <-> D-Ribose + Xanthine
H2O + P1,P3-Bis(5'-adenosyl) triphosphate <-> ADP + AMP
ATP + GDP <-> ADP + GTP
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate <-> CO2 + Aminoimidazole ribotide
NADP+ + NH3 + IMP <-> H+ + NADPH + GMP
H2O + dAMP <-> Phosphate + Deoxyadenosine
Phosphate + Adenosine <-> Adenine + alpha-D-Ribose 1-phosphate
H2O + dADP + Oxidized thioredoxin <-> ADP + Reduced thioredoxin
H2O + dITP <-> Diphosphate + dIMP
Pyruvate + dATP <-> Phosphoenolpyruvate + dADP
Phosphate + Inosine <-> Hypoxanthine + alpha-D-Ribose 1-phosphate
D-Ribose 1-phosphate <-> D-Ribose 5-phosphate
H2O + dGMP <-> Phosphate + Deoxyguanosine
Pyruvate + ATP <-> Phosphoenolpyruvate + ADP
ATP + GTP <-> AMP + Guanosine 3'-diphosphate 5'-triphosphate
H2O + GTP <-> Diphosphate + GMP
Phosphate + Guanosine <-> Guanine + alpha-D-Ribose 1-phosphate
H2O + 5-Ureido-4-imidazole carboxylate <-> CO2 + NH3 + 5-Amino-4-imidazole carboxylate
ATP + Deoxyadenosine <-> ADP + dAMP
AMP + NTP <-> ADP + NDP
ATP + D-Ribose 5-phosphate <-> AMP + 5-Phospho-alpha-D-ribose 1-diphosphate
H2O + Guanosine <-> Guanine + D-Ribose
Diphosphate + GMP <-> Guanine + 5-Phospho-alpha-D-ribose 1-diphosphate
H2O + GDP <-> Phosphate + GMP
ATP + Adenylylsulfate <-> P1,P4-Bis(5'-adenosyl) tetraphosphate + Sulfate
H2O + Guanosine 3'-phosphate <-> Phosphate + Guanosine
H2O + dITP <-> Phosphate + dIMP
H+ + 5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate <-> CO2 + (S)(+)-Allantoin
ATP + NH3 + XMP <-> Diphosphate + AMP + GMP
H2O + P1,P4-Bis(5'-xanthosyl) tetraphosphate <-> XMP + XTP
ATP + dAMP <-> ADP + dADP
H2O + Adenosine-5'-phospho-N-methylimidazolide <-> AMP + N-Methylimidazole
H2O + 3'-Phosphoadenylyl sulfate <-> Adenosine 3',5'-bisphosphate + Sulfate
H2O + O2 + Hypoxanthine <-> Xanthine + H2O2
H2O + 5-Aminoimidazole <-> NH3 + 5-Imidazolone
H2O + P1,P4-Bis(5'-guanosyl) tetraphosphate <-> GTP + GMP
ADP + H2O <-> Phosphate + AMP
ATP + Formate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <-> ADP + Phosphate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
NADP+ + 2-Hydroxypurine <-> H+ + NADPH + Xanthine
H2O + 5'-O-[acetoxy(hydroxy)phosphoryl]adenosine <-> AMP + Acetate
H2O + (-)-Ureidoglycolate <-> CO2 + 2 NH3 + Glyoxylate
ATP + NH3 + D-Ribose 5-phosphate <-> ADP + Phosphate + 5-Phospho-beta-D-ribosylamine
H2O + ADPribose <-> AMP + D-Ribose 1-phosphate
ATP + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine <-> ADP + Phosphate + Aminoimidazole ribotide
H2O + AMP <-> Adenine + D-Ribose 5-phosphate
H2O + XTP <-> Diphosphate + XMP
Phosphate + Xanthosine <-> alpha-D-Ribose 1-phosphate + Xanthine
ATP + ADP <-> ATP + ADP
H2O + O2 + Urate <-> H2O2 + 5-Hydroxyisourate
Diphosphate + AMP <-> Adenine + 5-Phospho-alpha-D-ribose 1-diphosphate
NAD+ + (-)-Ureidoglycolate <-> NADH + H+ + Oxalureate
Diphosphate + IMP <-> 5-Phospho-alpha-D-ribose 1-diphosphate + Hypoxanthine
N-Formiminoglycine <-> H2O + 5-Imidazolone
H2O + P1,P4-Bis(5'-adenosyl) tetraphosphate <-> ATP + AMP
H+ + NADPH + O2 <-> NADP+ + H2O2
ATP + H2O <-> ADP + Phosphate
Phosphate + Urate-3-ribonucleoside <-> D-Ribose 1-phosphate + Urate
H2O + ITP <-> Diphosphate + IMP
dATP + DNA <-> Diphosphate + DNA
10-Formyltetrahydrofolate + 5'-Phosphoribosylglycinamide <-> 5,6,7,8-Tetrahydrofolate + 5'-Phosphoribosyl-N-formylglycinamide
(-)-Ureidoglycolate <-> Urea + Glyoxylate
NAD+ + H2O + IMP <-> NADH + H+ + XMP
ATP + IDP <-> ADP + ITP
Diphosphate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <-> 5-Phospho-alpha-D-ribose 1-diphosphate + 5-Amino-4-imidazolecarboxyamide
ATP + dGDP <-> ADP + dGTP
NAD+ + H2O + Xanthine <-> NADH + H+ + Urate
NADP+ + Hypoxanthine <-> H+ + NADPH + Xanthine
H2O + AMP <-> NH3 + IMP
ATP + Adenylylsulfate <-> ADP + 3'-Phosphoadenylyl sulfate
ATP + H2O + L-Glutamine + XMP <-> L-Glutamate + Diphosphate + AMP + GMP
dGTP + DNA <-> Diphosphate + DNA
H2O + Guanosine 3',5'-bis(diphosphate) <-> Diphosphate + GDP
Phosphate + RNA <-> GDP + RNA
ATP + Formate + 5'-Phosphoribosylglycinamide <-> ADP + Phosphate + 5'-Phosphoribosyl-N-formylglycinamide
Pyruvate + dGTP <-> Phosphoenolpyruvate + dGDP
L-Aspartate + GTP + IMP <-> Phosphate + GDP + N6-(1,2-Dicarboxyethyl)-AMP
H2O + IDP <-> Phosphate + IMP
H2O + 3',5'-Cyclic AMP <-> AMP
ATP + RNA <-> Diphosphate + RNA
H2O + 5-Hydroxyisourate <-> 5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
H2O + GMP <-> Phosphate + Guanosine
1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole <-> 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + Fumarate
H2O + dATP + Oxidized thioredoxin <-> ATP + Reduced thioredoxin
H2O + Deoxyadenosine <-> NH3 + Deoxyinosine
H2O + Ureidoglycine <-> NH3 + (-)-Ureidoglycolate
ATP <-> Diphosphate + 3',5'-Cyclic AMP
Pyruvate + GTP <-> Phosphoenolpyruvate + GDP
Phosphate + RNA <-> ADP + RNA
H2O + 4-Nitrophenyl phosphate <-> Phosphate + p-Nitrophenol
1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide <-> H2O + IMP
H2O + Guanosine 3'-diphosphate 5'-triphosphate <-> Phosphate + Guanosine 3',5'-bis(diphosphate)
Diphosphate + XMP <-> 5-Phospho-alpha-D-ribose 1-diphosphate + Xanthine
5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole <-> 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
ATP + Sulfate <-> Diphosphate + Adenylylsulfate
H2O + Oxidized thioredoxin + dGTP <-> GTP + Reduced thioredoxin
H2O + 2',3'-Cyclic GMP <-> Guanosine 3'-phosphate
CO2 + 5-Aminoimidazole <-> 5-Amino-4-imidazole carboxylate
Phosphate + RNA <-> RNA + NDP
H2O + Allantoate <-> CO2 + NH3 + Ureidoglycine
Phosphate + Guanosine <-> Guanine + D-Ribose 1-phosphate
Phosphate + Deoxyadenosine <-> Adenine + 2-Deoxy-D-ribose 1-phosphate
H2O + Inosine 5'-tetraphosphate <-> Phosphate + ITP
ATP + Guanosine <-> ADP + GMP
ATP + Deoxyguanosine <-> ADP + dGMP
H2O + Adenosine <-> Adenine + D-Ribose
ATP + H2O <-> Diphosphate + AMP
H2O + 3',5'-Cyclic GMP <-> GMP
H2O + 5'-Benzoylphosphoadenosine <-> AMP + Benzoate
H2O + Adenosine 5'-tetraphosphate <-> ATP + Phosphate
H2O + Adenine <-> NH3 + Hypoxanthine
H2O + (S)(+)-Allantoin <-> Allantoate
ATP + Glycine + 5-Phospho-beta-D-ribosylamine <-> ADP + Phosphate + 5'-Phosphoribosylglycinamide
GTP + RNA <-> Diphosphate + RNA
Carbamoyl phosphate + Oxamate <-> Phosphate + Oxalureate
H2O + 2',3'-Cyclic AMP <-> Adenosine 3'-phosphate
ATP + dGMP <-> ADP + dGDP
NADP+ + Purine <-> H+ + NADPH + Xanthine
H2O + Oxidized thioredoxin + dGDP <-> GDP + Reduced thioredoxin
H2O + dGTP <-> dGMP + Diphosphate
N6-(1,2-Dicarboxyethyl)-AMP <-> AMP + Fumarate
GTP <-> Diphosphate + 3',5'-Cyclic GMP
Phosphate + Adenosine <-> Adenine + D-Ribose 1-phosphate
ATP + dADP <-> ADP + dATP
ATP + CO2 + NH3 <-> ADP + Carbamoyl phosphate
ATP + Inosine <-> ADP + IMP
Phosphate + Inosine <-> Hypoxanthine + D-Ribose 1-phosphate
NADP+ + (-)-Ureidoglycolate <-> H+ + NADPH + Oxalureate
H+ + 5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate <-> CO2 + (R)(-)-Allantoin
H2O + Allantoate <-> Urea + (-)-Ureidoglycolate
H2O + 5'-Butyrylphosphoinosine <-> IMP + Butanoate
L-Glutamate + Diphosphate + 5-Phospho-beta-D-ribosylamine <-> H2O + L-Glutamine + 5-Phospho-alpha-D-ribose 1-diphosphate
H2O + ADPribose <-> AMP + D-Ribose 5-phosphate
H2O + XMP <-> Phosphate + Xanthosine
H2O + IMP <-> D-Ribose 5-phosphate + Hypoxanthine
10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <-> 5,6,7,8-Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
H2O + P1,P4-Bis(5'-adenosyl) tetraphosphate <-> 2 ADP
H2O + Urea <-> CO2 + 2 NH3
(S)(+)-Allantoin <-> (R)(-)-Allantoin
ATP + Aminoimidazole ribotide + Hydrogencarbonate <-> ADP + Phosphate + 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole
 Classification
Nucleotide Metabolism
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