Pathway Details

 Recommended name Biosynthesis of secondary metabolites
 Alternative names
 Reactions
Novobiocic acid + dTDP-L-noviose <-> dTDP + Desmethyldescarbamoylnovobiocin
H+ + NADPH + O2 + (S)-N-Methylcoclaurine <-> H2O + NADP+ + 3'-Hydroxy-N-methyl-(S)-coclaurine
S-Adenosyl-L-methionine + 5,8,13,13a-Tetrahydrocolumbamine <-> S-Adenosyl-L-homocysteine + Tetrahydropalmatine
Isopentenyl diphosphate + trans,trans-Farnesyl diphosphate <-> Diphosphate + Geranylgeranyl diphosphate
L-Serine + (3-Indolyl)-glycerol phosphate <-> D-Glyceraldehyde 3-phosphate + H2O + L-Tryptophan
Phosphate + Xanthosine <-> D-Ribose 1-phosphate + Xanthine
Copalyl diphosphate <-> Diphosphate + Palustradiene
H2O + Acyl-CoA + Isopenicillin N <-> Coenzyme A + Penicillin + L-2-Aminoadipate
ATP + 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol <-> ADP + 2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol
O2 + Hemoglobin <-> Oxyhemoglobin
L-Phenylalanine <-> NH3 + trans-Cinnamate
Gibberellin A14 aldehyde <-> Gibberellin A14
Pyruvate + L-Tyrosine <-> L-Alanine + 3-(4-Hydroxyphenyl)pyruvate
3 H+ + 3 NADPH + 3 O2 + Lanosterol <-> 3 H2O + 3 NADP+ + Formate + 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
S-Adenosyl-L-methionine + (S)-Norcoclaurine <-> S-Adenosyl-L-homocysteine + (S)-Coclaurine
3 H+ + 3 NADPH + 3 O2 + Obtusifoliol <-> 3 H2O + 3 NADP+ + Formate + 4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol
H+ + NADPH + O2 + Narbomycin <-> H2O + NADP+ + Pikromycin
(S)-2-Aceto-2-hydroxybutanoate <-> (R)-3-Hydroxy-3-methyl-2-oxopentanoate
H+ + NADPH + 5-Hydroxyferuloyl-CoA <-> NADP+ + Coenzyme A + 5-Hydroxyconiferaldehyde
beta-D-Fructose 1,6-bisphosphate + H2O <-> beta-D-Fructose 6-phosphate + Phosphate
L-Histidine <-> CO2 + Histamine
2 H2O + NADP+ + Salutaridine <-> H+ + NADPH + O2 + (R)-Reticuline
2 NAD+ + Coenzyme A + Mevalonate <-> 2 NADH + 2 H+ + 3-Hydroxy-3-methylglutaryl-CoA
2 H2O2 <-> 2 H2O + O2
H2O + 3-alpha(S)-Strictosidine <-> Tryptamine + Secologanin
ADP + D-Glucose <-> AMP + D-Glucose 6-phosphate
Tabersonine <-> Minovincinine
Acetyl-CoA + Leaf alcohol <-> Coenzyme A + (Z)-3-Hexen-1-ol acetate
L-Tryptophan + Dimethylallyl diphosphate <-> Diphosphate + 4-(3-Methylbut-2-enyl)-L-tryptophan
NADP+ + (+)-Neomenthol <-> H+ + NADPH + (-)-Menthone
3 O2 + Coproporphyrinogen III <-> 3 H2O2 + Coproporphyrin III
L-Tyrosine + 4-Hydroxyphenylglyoxylate <-> 3-(4-Hydroxyphenyl)pyruvate + L-4-Hydroxyphenylglycine
Coenzyme A + Citrate <-> H2O + Acetyl-CoA + Oxaloacetate
S-Adenosyl-L-methionine + Secologanate <-> S-Adenosyl-L-homocysteine + Secologanin
Chorismate <-> Prephenate
Tetracenomycin F1 <-> Tetracenomycin D3
NAD+ + H2O + N6-(L-1,3-Dicarboxypropyl)-L-lysine <-> NADH + H+ + L-Glutamate + L-2-Aminoadipate 6-semialdehyde
ATP + H2O + Mg2+ + Protoporphyrin <-> ADP + Phosphate + 2 H+ + Magnesium protoporphyrin
Glycine + Succinyl-CoA <-> Coenzyme A + CO2 + 5-Aminolevulinate
3'-Keto-3'-deoxy-AMP <-> 3'-Amino-3'-deoxy-AMP
H2O + ADP alpha-D-glucoside <-> AMP + D-Glucose 1-phosphate
UTP + D-Glucose 1-phosphate <-> Diphosphate + UDPglucose
Antheraxanthin <-> Capsanthin
Pelletierine <-> N-Methylpelletierine
dTDP-L-4-oxovancosamine <-> dTDP-L-vancosamine
L-Ascorbate + Violaxanthin <-> H2O + Dehydroascorbate + Antheraxanthin
AminoDHQ <-> H2O + AminoDHS
UDP-D-glucose + D-Fructose <-> UDP + Sucrose
12-Deoxyaklanonic acid <-> Aklanonic acid
Diphosphate + Phosphoribosyl-ATP <-> ATP + 5-Phospho-alpha-D-ribose 1-diphosphate
ATP + Dimethylallyl diphosphate <-> Diphosphate + N6-(delta2-Isopentenyl)-adenosine 5'-triphosphate
NADH + H+ + 3-Hydroxypyruvate <-> NAD+ + Glycerate
Taxa-4(20),11(12)-dien-5alpha-acetoxy-10beta-ol <-> 10-Deacetyl-2-debenzoylbaccatin III
N,N-Dihydroxy-L-tyrosine <-> H2O + CO2 + (Z)-4-Hydroxyphenylacetaldehyde-oxime
O2 + 2 Columbamine <-> 2 H2O + 2 Berberine
S-Adenosyl-L-methionine + 3,4-Dihydroxy-trans-cinnamate <-> S-Adenosyl-L-homocysteine + Ferulate
S-Adenosyl-L-methionine + Loganate <-> S-Adenosyl-L-homocysteine + Loganin
S-Adenosyl-L-methionine + 3',4',5,7-Tetrahydroxy-3-methoxyflavone <-> S-Adenosyl-L-homocysteine + 3',4',5-Trihydroxy-3,7-dimethoxyflavone
NADP+ + Coenzyme A + 4-Hydroxycinnamyl aldehyde <-> H+ + NADPH + 4-Coumaroyl-CoA
2 S-Adenosyl-L-methionine + dTDP-3-amino-3,4,6-trideoxy-D-glucose <-> 2 S-Adenosyl-L-homocysteine + dTDP-D-desosamine
NAD+ + Chanoclavine-I <-> NADH + H+ + Chanoclavine-I aldehyde
3 H2O + GTP <-> Diphosphate + Formate + 2,5-Diamino-6-hydroxy-4-(5'-phosphoribosylamino)-pyrimidine
Carminomycin <-> Daunorubicin
13-Deoxycarminomycin <-> 13-Dihydrocarminomycin
D-Glyceraldehyde 3-phosphate + D-Sedoheptulose 7-phosphate <-> D-Ribose 5-phosphate + D-Xylulose 5-phosphate
H2O + L-Cystathionine <-> L-Cysteine + NH3 + 2-Oxobutyrate
Loganate <-> 10-Deoxygeniposidic acid
H2O + 1D-myo-Inositol 3-phosphate <-> Phosphate + myo-Inositol
FAD + sn-Glycerol 3-phosphate <-> Glycerone phosphate + FADH2
ATP + Coenzyme A + trans-Cinnamate <-> Diphosphate + AMP + Cinnamoyl-CoA
Dimethylallyl diphosphate <-> Diphosphate + Isoprene
alpha-D-Glucose <-> beta-D-Glucose
ATP + 1-Amino-1-deoxy-scyllo-inositol <-> ADP + 1-Amino-1-deoxy-scyllo-inositol 4-phosphate
sn-3-O-(Geranylgeranyl)glycerol 1-phosphate + Geranylgeranyl diphosphate <-> Diphosphate + 2,3-Bis-O-(geranylgeranyl)glycerol 1-phosphate
10-Formyltetrahydrofolate + 5'-Phosphoribosylglycinamide <-> 5,6,7,8-Tetrahydrofolate + 5'-Phosphoribosyl-N-formylglycinamide
S-Adenosyl-L-methionine + 5-Hydroxyconiferyl alcohol <-> S-Adenosyl-L-homocysteine + Sinapyl alcohol
H2O + Phosphatidylcholine <-> Choline + 1,2-Diacyl-sn-glycerol 3-phosphate
2 S-Adenosyl-L-methionine + Coumermic acid + dTDP-5-dimethyl-L-lyxose <-> 2 S-Adenosyl-L-homocysteine + 2 dTDP + Coumermycin D
ATP + L-Aspartate + L-Citrulline <-> Diphosphate + AMP + N(omega)-(L-Arginino)succinate
H2O + AMP <-> NH3 + IMP
Tetracenomycin A2 <-> Tetracenomycin X
Geranylgeranyl diphosphate <-> Diphosphate + Taxa-4(5),11(12)-diene
5alpha-Cholest-7-en-3beta-ol <-> 5alpha-Cholest-8-en-3beta-ol
Coenzyme A + ITP + Succinate <-> Phosphate + IDP + Succinyl-CoA
(+)-Bornyl-diphosphate <-> Geranyl diphosphate
CDP-1,2-diacylglycerol + Choline <-> CMP + Phosphatidylcholine
Isopentenyl diphosphate <-> Dimethylallyl diphosphate
ATP + Coenzyme A + Anthranilate <-> Diphosphate + AMP + Anthranilyl-CoA
O2 + 2-Oxoglutarate + Naringenin <-> H2O + CO2 + Succinate + Apigenin
Gibberellin A7 <-> Gibberellin A3
H+ + NADPH + O2 + Formononetin <-> H2O + NADP+ + 2'-Hydroxyformononetin
Acetyl-CoA + Demethylphosphinothricin <-> Coenzyme A + N-Acetyldemethylphosphinothricin
Phosphoenolpyruvate + H2O + Iminoerythrose 4-phosphate <-> Phosphate + AminoDAHP
H+ + NADPH + O2 + Anhydrotetracycline <-> H2O + NADP+ + 12-Dehydrotetracycline
UDP-L-rhamnose + Quercetin 3-O-glucoside <-> UDP + Rutin
H2O + Polyneuridine aldehyde <-> Methanol + CO2 + 16-Epivellosimine
H2O + (R)-Pantothenate <-> beta-Alanine + (R)-Pantoate
Fe2+ + Protoporphyrin <-> 2 H+ + Heme
O2 + 2-Oxoglutarate + (+)-Dihydromyricetin <-> H2O + CO2 + Succinate + Myricetin
H2O + D-Glucose 6-phosphate <-> Phosphate + D-Glucose
ATP + L-Tyrosine <-> Diphosphate + AMP + L-Tyrosyl-[pcp]
H2O + Acetyl-CoA + 2,3,4,5-Tetrahydrodipicolinate <-> Coenzyme A + N-Acetyl-L-2-amino-6-oxopimelate
H2O + Limonene-1,2-epoxide <-> Limonene-1,2-diol
5-Deoxodihydrokalafungin <-> Dihydrokalafungin
Acetone cyanohydrin <-> Acetone + Cyanide
(1R,4R)-Dihydrocarvone <-> (4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone
NADP+ + Leucodelphinidin <-> H+ + NADPH + (+)-Dihydromyricetin
NADP+ + Coenzyme A + Sinapoyl aldehyde <-> H+ + NADPH + Sinapoyl-CoA
Geranyl diphosphate <-> Diphosphate + (-)-beta-Pinene
Aklavinone <-> epsilon-Rhodomycinone
O2 + 2 Bilirubin <-> 2 H2O + 2 Biliverdin
ATP + L-Glutamate + tRNA(Glu) <-> Diphosphate + AMP + L-Glutamyl-tRNA(Glu)
(R)-2,3-Dihydroxy-3-methylpentanoate <-> H2O + (S)-3-Methyl-2-oxopentanoate
NAD+ + H2O + L-Isoleucine <-> NADH + H+ + NH3 + 3-Methyl-2-oxopentanoate
PQQ + Shikimate <-> PQQH2 + 3-Dehydroshikimate
NAD+ + Farnesol <-> NADH + H+ + Farnesal
Isocitrate <-> H2O + cis-Aconitate
2-Pyrroline-2-carboxyl-[pcp] <-> Pyrrole-2-carboxyl-[pcp]
H2O + L-Arginine <-> NH3 + L-Citrulline
L-Serine + Glyoxylate <-> Glycine + 3-Hydroxypyruvate
beta-Keto-L-tyrosyl-[pcp] <-> 2-Hydroxy-beta-keto-L-tyrosyl-[pcp]
NAD+ + myo-Inositol <-> NADH + H+ + 2,4,6/3,5-Pentahydroxycyclohexanone
D-Fructose 1,6-bisphosphate <-> D-Glyceraldehyde 3-phosphate + Glycerone phosphate
NAD+ + 3-Isopropylmalate <-> NADH + H+ + 3-Carboxy-4-methyl-2-oxopentanoate
NADP+ + Dihydrozeatin <-> H+ + NADPH + Zeatin
S-Adenosyl-L-methionine + (S)-3'-Hydroxycoclaurine <-> S-Adenosyl-L-homocysteine + (S)-Norreticuline
2 H2O + NADP+ + Berbamunine <-> H+ + NADPH + O2 + (S)-N-Methylcoclaurine + (R)-N-Methylcoclaurine
ATP + AMP <-> 2 ADP
ATP + L-Aspartate + NH3 <-> L-Asparagine + Diphosphate + AMP
Acetyl-CoA + Taxa-4(20),11(12)-dien-5alpha-ol <-> Coenzyme A + Taxa-4(20),11(12)-dien-5alpha-yl acetate
H2O + Squalene <-> Diplopterol
NADPH + O2 + Campesterol <-> H2O + NADP+ + 22alpha-Hydroxy-campesterol
D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate <-> H2O + 3-(Imidazol-4-yl)-2-oxopropyl phosphate
Aphidicolan-16beta-ol <-> Aphidicolin
D-Glucose + Sinapoylcholine <-> Choline + 1-O-Sinapoyl-beta-D-glucose
Urdamycinone B <-> 104-2
NADP+ + 10-Deoxysarpagine <-> H+ + NADPH + Vellosimine
Tetracenomycin E <-> Tetracenomycin A2
UDPglucose + trans-Zeatin <-> UDP + trans-Zeatin-7-beta-D-glucoside
NAD+ + H2O + L-Valine <-> NADH + H+ + NH3 + alpha-Ketovaline
2-Oxoglutarate + O-Phospho-L-serine <-> L-Glutamate + 3-Phosphohydroxypyruvate
2-Hydroxy-2,3-dihydrogenistein <-> H2O + Genistein
D-Mannose 6-phosphate <-> beta-D-Fructose 6-phosphate
L-Tyrosine + O2 <-> H2O + L-Dopa
NADP+ + L-Homoserine <-> H+ + NADPH + L-Aspartate 4-semialdehyde
NAD+ + sn-Glycerol 1-phosphate <-> Glycerone phosphate + NADH + H+
Aklaviketone <-> Aklavinone
dTDP-L-oleandrose + Avermectin A1a aglycone <-> dTDP + Avermectin A1a monosaccharide
trans,trans-Farnesyl diphosphate <-> Diphosphate + Pentalenene
Uroporphyrinogen III <-> 4 CO2 + Coproporphyrinogen III
(R)-Acetoin <-> (S)-Acetoin
dTDP-3-dimethylamino-3,4,6-trideoxy-D-glucose + 3-O-Mycarosylerythronolide B <-> dTDP + Erythromycin D
Glutaryl-CoA + Acceptor <-> CO2 + Crotonoyl-CoA + Reduced acceptor
UDP-D-galactose + Kaempferol <-> UDP + Kaempferol 3-O-beta-D-galactoside
dTDP-L-oleandrose + Avermectin B1a monosaccharide <-> dTDP + Avermectin B1a
H+ + NADPH + O2 + Apigenin <-> H2O + NADP+ + Luteolin
D-Glucose 1-phosphate <-> D-Glucose 6-phosphate
NAD+ + Morphine <-> NADH + H+ + Morphinone
Acetate + Succinyl-CoA <-> Acetyl-CoA + Succinate
UDPgalactose + Kaempferol <-> UDP + Kaempferol 3-O-beta-D-galactoside
2 Acetyl-CoA <-> Coenzyme A + Acetoacetyl-CoA
H2O + Chlorophyll a <-> Phytol + Chlorophyllide a
S-Adenosyl-L-methionine + Protein C-terminal S-farnesyl-L-cysteine <-> S-Adenosyl-L-homocysteine + Protein C-terminal S-farnesyl-L-cysteine methyl ester
H+ + NADPH + O2 + 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester <-> 2 H2O + NADP+ + 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester
S-Adenosyl-L-methionine + Caffeic aldehyde <-> S-Adenosyl-L-homocysteine + Coniferaldehyde
S-Adenosyl-L-methionine + 5-Hydroxyconiferaldehyde <-> S-Adenosyl-L-homocysteine + Sinapoyl aldehyde
NAD+ + H2O + L-2-Aminoadipate 6-semialdehyde <-> NADH + H+ + L-2-Aminoadipate
Tabersonine <-> 19-Hydroxytabersonine
L-Glutamate 5-semialdehyde <-> H2O + (S)-1-Pyrroline-5-carboxylate
NAD+ + (R)-3-(4-Hydroxyphenyl)lactate <-> NADH + H+ + 3-(4-Hydroxyphenyl)pyruvate
trans,trans-Farnesyl diphosphate <-> Diphosphate + Vetispiradiene
UDP-D-glucose + Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside <-> UDP + Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside
NADPH + O2 + Campestanol <-> H2O + NADP+ + 6-Deoxocathasterone
ATP + D-Glycerate <-> ADP + 3-Phospho-D-glycerate
Dopamine + 4-Hydroxyphenylacetaldehyde <-> H2O + (S)-Norcoclaurine
3-Dehydroshikimate <-> H2O + 3,4-Dihydroxybenzoate
dTDPglucose <-> H2O + dTDP-4-dehydro-6-deoxy-D-glucose
H+ + NADPH + O2 + Loganate <-> 2 H2O + NADP+ + Secologanate
S-Adenosyl-L-methionine + N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate <-> S-Adenosyl-L-homocysteine + N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate
Proansamycin X <-> 34a-Deoxy-rifamycin W
H+ + NADPH + O2 + Loganin <-> 2 H2O + NADP+ + Secologanin
L-Tyrosine <-> NH3 + 4-Coumarate
UDPglucose + (1,4-alpha-D-Glucosyl)n <-> UDP + (1,4-alpha-D-Glucosyl)n
NADP+ + Shikimate <-> H+ + NADPH + 3-Dehydroshikimate
1-Methylpyrrolinium <-> Hygrine
H2O + 17-O-Acetylnorajmaline <-> Acetate + Norajmaline
2 NAD+ + H2O + L-Histidinal <-> 2 NADH + H+ + L-Histidine
NADP+ + Codeine <-> H+ + NADPH + 7,8-Didehydro-4,5-epoxy-3-methoxy-17-methoxy-(5_)-morphinan-6-one
ATP + Shikimate <-> ADP + Shikimate 3-phosphate
Isopenicillin N <-> Penicillin N
D-Glucose + Ubiquinone <-> D-Glucono-1,5-lactone + Ubiquinol
H2O + O-Phospho-L-homoserine <-> Phosphate + L-Threonine
Secologanin + Dopamine <-> H2O + Deacetylisoipecoside
Geranylgeranyl diphosphate <-> Diphosphate + Casbene
H+ + NADPH + O2 + Kaur-16-en-18-oic acid <-> H2O + NADP+ + ent-7alpha-Hydroxykaur-16-en-19-oic acid
L-Serine + CDP-1,2-diacylglycerol <-> CMP + Phosphatidylserine
H2O + NADP+ + N6-(L-1,3-Dicarboxypropyl)-L-lysine <-> H+ + L-Glutamate + NADPH + L-2-Aminoadipate 6-semialdehyde
NAD+ + L-Malate <-> NADH + H+ + Oxaloacetate
Pyruvate + 1D-1-Guanidino-3-amino-1,3-dideoxy-scyllo-inositol <-> L-Alanine + 1D-1-Guanidino-1-deoxy-3-dehydro-scyllo-inositol
H2O + 3-alpha(S)-Strictosidine <-> D-Glucose + Strictosidine aglycone
(+)-cis-Isopulegone <-> Pulegone
beta-D-Fructose 6-phosphate + D-Glyceraldehyde 3-phosphate <-> D-Xylulose 5-phosphate + D-Erythrose 4-phosphate
Coenzyme A + Homocitrate <-> H2O + Acetyl-CoA + 2-Oxoglutarate
S-Adenosyl-L-methionine <-> 5'-Deoxy-5'-(methylthio)adenosine + 1-Aminocyclopropane-1-carboxylate
L-Serine + Sulfide <-> H2O + L-Cysteine
beta-D-Fructose 6-phosphate + ATP <-> beta-D-Fructose 1,6-bisphosphate + ADP
L-Proline + Acceptor <-> Reduced acceptor + (S)-1-Pyrroline-5-carboxylate
NADP+ + sn-Glycerol 3-phosphate <-> Glycerone phosphate + H+ + NADPH
2 NADP+ + Coenzyme A + (R)-Mevalonate <-> 2 H+ + 2 NADPH + 3-Hydroxy-3-methylglutaryl-CoA
H2O + N2-Acetyl-L-ornithine <-> Acetate + L-Ornithine
H2O + Phosphatidylcholine <-> Choline phosphate + 1,2-Diacyl-sn-glycerol
H2O + Squalene <-> Tetrahymanol
ATP + Coenzyme A + 4-Coumarate <-> Diphosphate + AMP + 4-Coumaroyl-CoA
H+ + NADPH + O2 + trans-Cinnamate <-> H2O + NADP+ + 4-Coumarate
UDPglucose + 2-Coumarate <-> UDP + trans-beta-D-Glucosyl-2-hydroxycinnamate
H+ + NADPH + O2 + Kaur-16-en-18-ol <-> 2 H2O + NADP+ + Kaur-16-en-18-al
S-Adenosyl-L-methionine + Nogalonic acid <-> H+ + S-Adenosyl-L-homocysteine + Nogalonic acid methyl ester
S-Adenosyl-L-methionine + Putrescine <-> S-Adenosyl-L-homocysteine + N-Methylputrescine
L-Ornithine <-> CO2 + Putrescine
Phosphate + NADP+ + L-Glutamate 5-semialdehyde <-> H+ + NADPH + L-Glutamyl 5-phosphate
ATP + L-Glutamate <-> ADP + L-Glutamyl 5-phosphate
S-Adenosyl-L-homocysteine + Erythromycin B <-> S-Adenosyl-L-methionine + Erythromycin D
ATP + alpha-D-Glucose 1-phosphate <-> Diphosphate + ADP alpha-D-glucoside
Phosphate + Starch <-> alpha-D-Glucose 1-phosphate + Amylose
H+ + NADPH + O2 + Abscisate <-> H2O + NADP+ + 8'-Hydroxyabscisate
H+ + NADPH + O2 + Taxifolin <-> H2O + NADP+ + (+)-Dihydromyricetin
Carbamoyl phosphate + Descarbamoylnovobiocin <-> Phosphate + Novobiocin
H+ + NADPH + O2 + trans-Cinnamate <-> H2O + NADP+ + 2-Coumarate
ATP + Acetyl-CoA + Hydrogencarbonate <-> ADP + Phosphate + Malonyl-CoA
Cycloeucalenol <-> Obtusifoliol
alpha-D-Glucose 6-phosphate + UDPglucose <-> UDP + Trehalose 6-phosphate
GDPmannose <-> GDP-L-galactose
S-Adenosyl-L-methionine + 16-Hydroxytabersonine <-> H+ + S-Adenosyl-L-homocysteine + 16-Methoxytabersonine
O2 + Reduced acceptor + Neurosporene <-> 2 H2O + Acceptor + Lycopene
NADP+ + dTDP-L-rhamnose <-> H+ + NADPH + dTDP-4-dehydro-beta-L-rhamnose
Erythromycin C + dTDP-L-megosamine <-> dTDP + Megalomicin A
NAD+ + Phenyllactate <-> NADH + H+ + Phenylpyruvate
NAD+ + L-Histidinol <-> NADH + H+ + L-Histidinal
NADP+ + Coenzyme A + Cinnamaldehyde <-> H+ + NADPH + Cinnamoyl-CoA
NAD+ + (S,S)-2,3-Butanediol <-> NADH + H+ + (S)-Acetoin
ATP + Coenzyme A + Citrate <-> ADP + Phosphate + Acetyl-CoA + Oxaloacetate
ATP + Protochlorophyllide <-> ADP + Phosphate + Chlorophyllide a
CTP + 2-C-Methyl-D-erythritol 4-phosphate <-> Diphosphate + 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol
dTDP-4-amino-4,6-dideoxy-D-glucose + 2-Oxoglutarate <-> L-Glutamate + dTDP-4-dehydro-6-deoxy-D-glucose
S-Adenosyl-L-methionine + N-Acetyl-O-demethylpuromycin <-> S-Adenosyl-L-homocysteine + N-Acetylpuromycin
S-Adenosyl-L-methionine + Novclobiocin 105 <-> S-Adenosyl-L-homocysteine + Novclobiocin 104
Rifamycin W-hemiacetal <-> Demethyl-desacetyl-rifamycin S
NADP+ + dTDP-D-fucose <-> H+ + NADPH + 4,6-Dideoxy-4-oxo-dTDP-D-glucose
Coenzyme A + L-Malate <-> H2O + Acetyl-CoA + Glyoxylate
H+ + L-Lysine + NADPH + O2 <-> H2O + NADP+ + N6-Hydroxy-L-lysine
NADP+ + 4-Coumaryl alcohol <-> H+ + NADPH + 4-Hydroxycinnamyl aldehyde
H2O + O2 + Cephalosporin C <-> NH3 + H2O2 + 7-(5-Carboxyl-5-oxopentanyl)-aminocephalosporinate
Starch <-> Maltose + Maltodextrin
2 H+ + Siroheme <-> Fe2+ + Sirohydrochlorin
Strictosidine aglycone <-> Dialdehyde
Coenzyme A + 3-Hydroxy-3-methylglutaryl-CoA <-> H2O + Acetyl-CoA + Acetoacetyl-CoA
2,5,7,4'-Tetrahydroxyisoflavanone <-> H2O + Genistein
delta-Carotene <-> alpha-Carotene
Homocitrate <-> H2O + But-1-ene-1,2,4-tricarboxylate
1D-myo-Inositol 3-phosphate <-> D-Glucose 6-phosphate
Acetyl-CoA + Minovincinine <-> Coenzyme A + Echitovenine
NAD+ + Coenzyme A + 2-Oxoglutarate <-> NADH + H+ + CO2 + Succinyl-CoA
NADP+ + 2,3,4,5-Tetrahydrodipicolinate <-> H+ + NADPH + L-2,3-Dihydrodipicolinate
H+ + L-Tyrosine + NADPH + O2 <-> H2O + NADP+ + N-Hydroxy-L-tyrosine
CTP + 1,2-Diacyl-sn-glycerol 3-phosphate <-> Diphosphate + CDP-1,2-diacylglycerol
NADP+ + Ergosterol <-> H+ + NADPH + Ergosta-5,7,22,24(28)-tetraen-3beta-ol
NAD+ + UDPglucose <-> NADH + H+ + UDP-3-ketoglucose
H+ + NADPH + O2 + ent-Kaurene <-> H2O + NADP+ + Kaur-16-en-18-ol
L-Threonine <-> NH3 + 2-Oxobutyrate
Geranyl diphosphate <-> Diphosphate + Myrcene
S-Adenosyl-L-methionine + Xanthosine <-> S-Adenosyl-L-homocysteine + 7-Methylxanthosine
Acetyl-CoA + 10-Deacetylbaccatin III <-> Coenzyme A + Baccatin III
ATP + L-Homoserine <-> ADP + O-Phospho-L-homoserine
H2O + Oxidized dithiothreitol + Phylloquinone <-> 1,4-Dithiothreitol + Vitamin K epoxide
H+ + NADPH + O2 + (+)-Limonene <-> H2O + NADP+ + (+)-trans-Carveol
H+ + NADPH + O2 + (Z)-4-Hydroxyphenylacetaldehyde-oxime <-> 2 H2O + NADP+ + (S)-4-Hydroxymandelonitrile
ATP + myo-Inositol <-> ADP + 1D-myo-Inositol 3-phosphate
(-)-alpha-Terpineol <-> 1,8-Cineole
O2 + D-Ribulose 1,5-bisphosphate <-> 2-Phosphoglycolate + 3-Phospho-D-glycerate
H2O + Geranyl diphosphate <-> Diphosphate + Geraniol
trans,trans-Farnesyl diphosphate + Protein cysteine <-> Diphosphate + S-Farnesyl protein
Phenanthroviridone aglycon <-> Jadomycin B
H+ + NADPH + O2 + Eriodictyol <-> H2O + NADP+ + Pentahydroxyflavanone
O2 + Glycolate <-> Glyoxylate + H2O2
Oxaloacetate + L-Arogenate <-> L-Aspartate + Prephenate
Oxidized ferredoxin + (3Z)-Phytochromobilin <-> Reduced ferredoxin + Biliverdin
27-O-Demethyl-rifamycin SV <-> Rifamycin
2 L-Glutamate + NADP+ <-> H+ + L-Glutamine + NADPH + 2-Oxoglutarate
3 Malonyl-CoA <-> H2O + 3,5-Dihydroxyphenylacetyl-CoA
NADP+ + Tropine <-> H+ + NADPH + Tropinone
Heme <-> Heme O
S-Adenosyl-L-methionine + Avermectin B1b aglycone <-> S-Adenosyl-L-homocysteine + Avermectin A1b aglycone
NAD+ + Bilirubin <-> NADH + H+ + Biliverdin
4,6-Dideoxy-4-oxo-dTDP-D-glucose <-> dTDP-4-dehydro-beta-L-rhamnose
L-Arginine + N1-Amidinostreptamine 6-phosphate <-> L-Ornithine + Streptidine 6-phosphate
H+ + NADPH + O2 + Kaempferol <-> H2O + NADP+ + Quercetin
UDP-D-glucose + Zeatin <-> UDP + O-beta-D-Glucosylzeatin
UDPglucose + 4-Coumaryl alcohol <-> UDP + 4-Hydroxycinnamyl alcohol 4-D-glucoside
S-Adenosyl-L-methionine + Aklanonic acid <-> H+ + S-Adenosyl-L-homocysteine + Aklanonic acid methyl ester
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate <-> CO2 + Aminoimidazole ribotide
UDP-D-glucose + Coniferyl alcohol <-> UDP + Coniferin
S-Adenosyl-L-methionine + 4-Demethylpremithramycinone <-> H+ + S-Adenosyl-L-homocysteine + Premithramycinone
Isopentenyl diphosphate + Geranyl diphosphate <-> Diphosphate + trans,trans-Farnesyl diphosphate
NADP+ + cis-3,4-Leucopelargonidin <-> H+ + NADPH + Dihydrokaempferol
H2O + alpha,alpha-Trehalose <-> 2 D-Glucose
Kanosamine 6-phosphate <-> Aminofructose 6-phosphate
H+ + NADPH + 3 Malonyl-CoA + 4-Coumaroyl-CoA <-> H2O + NADP+ + 4 Coenzyme A + 3 CO2 + Isoliquiritigenin
Phytyl diphosphate + Chlorophyllide a <-> Diphosphate + Chlorophyll a
Homoisocitrate <-> H2O + But-1-ene-1,2,4-tricarboxylate
S-Adenosyl-L-methionine + Demethylmacrocin <-> S-Adenosyl-L-homocysteine + Macrocin
O2 + 2-Oxoglutarate + cis-3,4-Leucopelargonidin <-> H2O + CO2 + Succinate + Dihydrokaempferol
Ethanol + NADP+ <-> H+ + NADPH + Acetaldehyde
3-Phospho-D-glycerate <-> 2-Phospho-D-glycerate
2 Putrescine <-> NH3 + Homospermidine
H2O + 6-Phospho-D-glucono-1,5-lactone <-> 6-Phospho-D-gluconate
ATP + Coenzyme A + 2-Succinylbenzoate <-> Diphosphate + AMP + 2-Succinylbenzoyl-CoA
Dopamine + 3,4-Dihydroxyphenylacetaldehyde <-> H2O + (S)-Norlaudanosoline
ATP + D-Glucose 1-phosphate <-> Diphosphate + ADP alpha-D-glucoside
H2O + O-Phospho-L-serine <-> Phosphate + L-Serine
NAD+ + L-Lactate <-> Pyruvate + NADH + H+
4,21-Dehydrogeissoschizine <-> Cathenamine
NAD+ + Coenzyme A + 2-Oxoadipate <-> NADH + H+ + CO2 + Glutaryl-CoA
alpha-D-Glucose 1-phosphate <-> alpha-D-Glucose 6-phosphate
H2O + Glucose 6-phosphate <-> Phosphate + D-Glucose
D-Ribose 5-phosphate <-> D-Ribulose 5-phosphate
H+ + NADPH + O2 + Ferulate <-> H2O + NADP+ + 5-Hydroxyferulate
4-Hydroxybenzoate + n Polyisopentenylpyrophosphate <-> n Diphosphate + 4-Hydroxy-3-polyprenylbenzoate
NADP+ + D-Glucose <-> H+ + NADPH + D-Glucono-1,5-lactone
Demethyl-desacetyl-rifamycin S <-> Demethyl-desacetyl-rifamycin SV
(S)-4-Hydroxymandelonitrile <-> 4-Hydroxybenzaldehyde + Cyanide
4-Coumarate <-> CO2 + 4-Hydroxystyrene
dTDP-L-oleandrose + Avermectin A1b monosaccharide <-> dTDP + Avermectin A1b
O2 + 2-Oxoglutarate + Gibberellin A24 <-> CO2 + Succinate + Gibberellin A36
S-Adenosyl-L-methionine + 5-Hydroxyferuloyl-CoA <-> S-Adenosyl-L-homocysteine + Sinapoyl-CoA
dTDP-4-oxo-6-deoxy-D-allose <-> dTDP-6-deoxy-D-allose
H2O + L-Tyrosine + O2 <-> NH3 + H2O2 + 3-(4-Hydroxyphenyl)pyruvate
UDPglucose + Zeatin <-> UDP + O-beta-D-Glucosylzeatin
H2O + Malonyl-CoA + (S)-1-Pyrroline-5-carboxylate <-> Coenzyme A + CO2 + (2S,5S)-5-Carboxymethylproline
H2O + Geranyl diphosphate <-> Diphosphate + (+)-Linalool
D-Ribulose 5-phosphate <-> Formate + 3,4-Dihydroxy-2-butanone 4-phosphate
L-Ornithine + 2-Oxoglutarate <-> L-Glutamate + L-Glutamate 5-semialdehyde
dTDP-L-oleandrose + Avermectin A1b aglycone <-> dTDP + Avermectin A1b monosaccharide
Geranylgeranyl diphosphate <-> syn-Copalyl diphosphate
(1,4-alpha-D-Glucosyl)n <-> 1-alpha-D-{(1,4)-alpha-D-Glucosyl}(n-1)-alpha-D-glucopyranoside
5-Aminolevulinate <-> (S)-4-Amino-5-oxopentanoate
ATP + Oxaloacetate <-> Phosphoenolpyruvate + ADP + CO2
Gibberellin A36 <-> CO2 + Gibberellin A4
NAD+ + Precorrin 2 <-> NADH + H+ + Sirohydrochlorin
H2O + Atropine <-> Tropine + Tropate
Reduced ferredoxin + Biliverdin <-> Oxidized ferredoxin + 15,16-Dihydrobiliverdin
NAD+ + Isocitrate <-> NADH + H+ + CO2 + 2-Oxoglutarate
Amylose + ADP alpha-D-glucoside <-> ADP + Amylose
UDPglucose + Kaempferol 3-O-glucoside <-> UDP + Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside
UDP-D-glucose + 4-Coumaryl alcohol <-> UDP + 4-Hydroxycinnamyl alcohol 4-D-glucoside
Glycerone phosphate + L-Aspartate 4-semialdehyde <-> 2-Amino-4,5-dihydroxy-6-one-heptanoate-7-phosphate
AMP + Dimethylallyl diphosphate <-> Diphosphate + N6-(delta2-Isopentenyl)-adenosine 5'-monophosphate
Neoxanthin <-> 9'-cis-Neoxanthin
S-Adenosyl-L-methionine + Anthranilate <-> S-Adenosyl-L-homocysteine + N-Methylanthranilate
S-Adenosyl-L-methionine + N6-(delta2-Isopentenyl)-adenine <-> 5'-Deoxy-5'-(methylthio)adenosine + Discadenine
GTP + D-Mannose 1-phosphate <-> Diphosphate + GDP-D-mannose
(3-Indolyl)-glycerol phosphate <-> D-Glyceraldehyde 3-phosphate + Indole
ATP + L-N2-(2-Carboxyethyl)arginine <-> Diphosphate + AMP + Deoxyguanidinoproclavaminic acid
Gibberellin A20 <-> Gibberellin A5
3 O2 + 3 Reduced acceptor + Heme <-> 3 H2O + Fe2+ + Carbon monoxide + 3 Acceptor + Biliverdin
dTDP-3-amino-2,3,6-trideoxy-C-methyl-D-erythro-hexopyranos-4-ulose <-> dTDP-L-4-oxovancosamine
NAD+ + 3-(4-Hydroxyphenyl)lactate <-> NADH + H+ + 3-(4-Hydroxyphenyl)pyruvate
Stemmadenine <-> Tabersonine
ATP + Formate + 5'-Phosphoribosylglycinamide <-> ADP + Phosphate + 5'-Phosphoribosyl-N-formylglycinamide
Rifamycin Z <-> Demethyl-desacetyl-rifamycin S
NAD+ + Glycine + 5,6,7,8-Tetrahydrofolate <-> NADH + H+ + CO2 + NH3 + 5,10-Methylenetetrahydrofolate
UDP-D-glucose + Quercetin <-> UDP + Quercetin 3-O-glucoside
Stemmadenine <-> Catharanthine
NADP+ + (R)-2,3-Dihydroxy-3-methylbutanoate <-> H+ + NADPH + 3-Hydroxy-3-methyl-2-oxobutanoate
Acetyl-CoA + N6-Hydroxy-L-lysine <-> Coenzyme A + N6-Acetyl-N6-hydroxy-L-lysine
Tetracenomycin A2 <-> Tetracenomycin C
S-Adenosyl-L-methionine + N-Acetylserotonin <-> S-Adenosyl-L-homocysteine + Melatonin
NAD+ + L-Proline <-> NADH + H+ + (S)-1-Pyrroline-5-carboxylate
alpha-D-Glucose 6-phosphate + UDP-D-glucose <-> UDP + Trehalose 6-phosphate
2 S-Adenosyl-L-methionine + Coproporphyrinogen III <-> 2 L-Methionine + 2 CO2 + 2 5'-Deoxyadenosine + Protoporphyrinogen IX
Phosphate + Starch <-> D-Glucose 1-phosphate + Amylose
UDP-D-glucose + Scopoletin <-> UDP + Scopolin
H2O + 1,2-Diacyl-sn-glycerol 3-phosphate <-> Phosphate + 1,2-Diacyl-sn-glycerol
L-Cysteine + Cyanide <-> Hydrogen sulfide + 3-Cyano-L-alanine
UDP-D-glucose + Kaempferol <-> UDP + Kaempferol 3-O-glucoside
Phosphate + Diphosphate + S-Adenosyl-L-methionine <-> ATP + H2O + L-Methionine
H2O + Phosphoribosyl-ATP <-> Diphosphate + Phosphoribosyl-AMP
Isocitrate <-> Glyoxylate + Succinate
O2 + 2-Oxoglutarate + Gibberellin A9 <-> CO2 + Succinate + Gibberellin A51
3 Malonyl-CoA + 4-Coumaroyl-CoA <-> 4 Coenzyme A + 4 CO2 + 3,4',5-Trihydroxystilbene
H2O + Neurosporene <-> 1-Hydroxyneurosporene
2 S-Adenosyl-L-methionine + dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose <-> 2 S-Adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,4,6-trideoxy-D-glucose
5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole <-> 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
S-Adenosyl-L-methionine + Myricetin <-> S-Adenosyl-L-homocysteine + Laricitrin
Neoabietinol <-> Neoabietal
UDP-D-glucose + Vomilenine <-> UDP + Raucaffricine
delta-Carotene <-> Lycopene
16-Epivellosimine <-> Vellosimine
S-Adenosyl-L-methionine + (S)-Reticuline <-> S-Adenosyl-L-homocysteine + Laudanine
Mandelonitrile <-> Benzaldehyde + Cyanide
Copalyl diphosphate <-> Diphosphate + (-)-Abietadiene
H+ + NADPH + O2 + Senecionine <-> H2O + NADP+ + Senecionine N-oxide
H+ + NADPH + O2 + N-Hydroxy-L-tyrosine <-> H2O + NADP+ + N,N-Dihydroxy-L-tyrosine
Rhodomycin D <-> 10-Carboxy-13-deoxycarminomycin
L-Malate <-> H2O + Fumarate
Ajmalicine <-> Serpentine
H2O + Raucaffricine <-> D-Glucose + Vomilenine
Aklanonic acid methyl ester <-> Aklaviketone
Hemoglobin <-> Heme + Globin
(S)-2-Acetolactate <-> CO2 + (R)-Acetoin
UDPglucose + Quercetin <-> UDP + Quercetin 3-O-glucoside
H2O + N-Acetylpuromycin <-> Acetate + Puromycin
Malonyl-CoA + 4'''-Demalonylsalvianin <-> Coenzyme A + Salvianin
H2O + Cephalosporin C <-> Acetate + Deacetylcephalosporin C
NADP+ + dTDP-6-deoxy-L-talose <-> H+ + NADPH + dTDP-4-dehydro-beta-L-rhamnose
L-Cysteine + Cyanide <-> 3-Cyano-L-alanine + Sulfide
5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide <-> N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide
Isonocardicin A <-> Nocardicin A
H+ + NADPH + O2 + Vinorine <-> H2O + NADP+ + Vomilenine
H2O + Crotonoyl-CoA <-> 3-Hydroxybutanoyl-CoA
H+ + NADPH + O2 + (6aR,11aR)-3,9-Dihydroxypterocarpan <-> H2O + NADP+ + (6aS,11aS)-3,6a,9-Trihydroxypterocarpan
Tabersonine <-> Lochnerinine
Violaxanthin <-> 9-cis-Violaxanthin
UDPglucose + Delphinidin <-> UDP + Delphinidin 3-O-glucoside
O2 + Coproporphyrinogen III <-> 2 H2O + 2 CO2 + Protoporphyrinogen IX
S-Adenosyl-L-methionine + Magnesium protoporphyrin <-> S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester
2,3-Dehydro-gibberellin A9 <-> Gibberellin A7
FAD + Butanoyl-CoA <-> Crotonoyl-CoA + FADH2
Demethyl-desacetyl-rifamycin SV <-> 27-O-Demethyl-rifamycin SV
H+ + NADPH + Caffeic aldehyde <-> NADP+ + Caffeyl alcohol
L-Serine + L-Homocysteine <-> H2O + L-Cystathionine
7,8-Didehydro-4,5-epoxy-3-methoxy-17-methoxy-(5_)-morphinan-6-one <-> Neopinone
Neoabietal <-> Neoabietic acid
Piperideine + Pelletierine <-> Anapheline
1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate <-> H2O + CO2 + (3-Indolyl)-glycerol phosphate
O2 + 2-Oxoglutarate + Deoxyguanidinoproclavaminic acid <-> CO2 + Succinate + Guanidinoproclavaminic acid
H+ + NADPH + O2 + Tabersonine <-> H2O + NADP+ + 16-Hydroxytabersonine
L-Valine + 2-Oxoglutarate <-> L-Glutamate + alpha-Ketovaline
Auraviketone <-> Auramycinone
L-Tyrosine <-> CO2 + Tyramine
H+ + NADPH + 3-Phospho-D-glyceroyl phosphate <-> D-Glyceraldehyde 3-phosphate + Phosphate + NADP+
(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA <-> H2O + 2-Methylbut-2-enoyl-CoA
L-Ornithine <-> D-Ornithine
H+ + NADPH + O2 + 6-Oxocineole <-> H2O + NADP+ + 1,6,6-Trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one
S-Adenosyl-L-methionine + dTDP-3-amino-2,3,6-trideoxy-D-threo-hexopyranos-4-ulose <-> S-Adenosyl-L-homocysteine + dTDP-3-amino-2,3,6-trideoxy-C-methyl-D-erythro-hexopyranos-4-ulose
4-Hydroxybenzoate + Geranyl diphosphate <-> Diphosphate + 3-Geranyl-4-hydroxybenzoate
S-Adenosyl-L-methionine + 16-Methoxy-2,3-dihydro-3-hydroxytabersonine <-> S-Adenosyl-L-homocysteine + Desacetoxyvindoline
NADP+ + Coniferyl alcohol <-> H+ + NADPH + Coniferaldehyde
Dimethylallyl diphosphate + Isopentenyl diphosphate <-> Diphosphate + Geranyl diphosphate
H2O + O-Phospho-L-serine <-> Phosphate + Serine
Pyruvate + ATP + H2O <-> Phosphoenolpyruvate + Phosphate + AMP
S-Adenosyl-L-methionine + Premithramycin A3' <-> H+ + S-Adenosyl-L-homocysteine + Premithramycin A3
3-Dimethylallyl-beta-hydroxy-L-tyrosyl-[pcp] <-> 3-Dimethylallyl-4-hydroxybenzaldehyde
alpha-D-Glucose + (Phosphate)n <-> alpha-D-Glucose 6-phosphate + (Phosphate)n
ATP + 3-Phospho-D-glycerate <-> ADP + 3-Phospho-D-glyceroyl phosphate
ent-Copalyl diphosphate <-> Diphosphate + ent-Kaurene
Glycine + 2-Oxoglutarate <-> L-Glutamate + Glyoxylate
(9Z)-(13S)-12,13-Epoxyoctadeca-9,11,15-trienoate <-> (15Z)-12-Oxophyto-10,15-dienoate
O2 + 2-Oxoglutarate + DIBOA glucoside <-> H2O + CO2 + Succinate + TRIBOA glucoside
H2O + 4-Hydroxycinnamyl alcohol 4-D-glucoside <-> D-Glucose + 4-Coumaryl alcohol
Benzoyl-CoA + 10-Deacetyl-2-debenzoylbaccatin III <-> Coenzyme A + 10-Deacetylbaccatin III
Coenzyme A + GTP + Succinate <-> Phosphate + GDP + Succinyl-CoA
Caffeoyl-CoA + Quinate <-> Coenzyme A + Chlorogenate
Gibberellin A9 <-> Gibberellin A20
ATP + Coenzyme A + Sinapate <-> Diphosphate + AMP + Sinapoyl-CoA
ATP + NAD+ <-> NADH + H+ + 3'-Keto-3'-deoxy-ATP
4-Coumaryl alcohol <-> Caffeyl alcohol
H2O + NADP+ + N6-(L-1,3-Dicarboxypropyl)-L-lysine <-> H+ + L-Lysine + NADPH + 2-Oxoglutarate
2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate <-> Phosphate + 3-Dehydroquinate
H+ + NADPH + O2 + Abietadienol <-> 2 H2O + NADP+ + Abietadienal
NAD+ + 2,3,4,5-Tetrahydrodipicolinate <-> NADH + H+ + L-2,3-Dihydrodipicolinate
H2O + Chlorophyll b <-> Phytol + Chlorophyllide b
sn-Glycerol 3-phosphate + Acyl-CoA <-> Coenzyme A + 1-Acyl-sn-glycerol 3-phosphate
CO2 + 2-Acetolactate <-> 2 Pyruvate
2-Succinylbenzoyl-CoA <-> H2O + 1,4-Dihydroxy-2-naphthoyl-CoA
trans-Cinnamate <-> Cocaine
Homospermidine <-> Trachelanthamidine
dTDP-D-glucose <-> H2O + dTDP-4-dehydro-6-deoxy-D-glucose
H2O + L-Arginine <-> L-Ornithine + Urea
Pyruvate + ATP <-> Phosphoenolpyruvate + ADP
NADP+ + Morphine <-> H+ + NADPH + Morphinone
L-Isoleucine + 2-Oxoglutarate <-> L-Glutamate + 3-Methyl-2-oxopentanoate
H2O + Geranyl diphosphate <-> Diphosphate + Sabinene hydrate
NADP+ + (-)-trans-Carveol <-> H+ + NADPH + (-)-Carvone
H2O + Dodecanoyl-[acyl-carrier protein] <-> Holo-[acyl-carrier protein] + Dodecanoate
(S)-2,3-Epoxysqualene <-> Lanosterol
NADP+ + 2-C-Methyl-D-erythritol 4-phosphate <-> H+ + NADPH + 1-Deoxy-D-xylulose 5-phosphate
S-Adenosyl-L-methionine + (S)-Scoulerine <-> S-Adenosyl-L-homocysteine + 5,8,13,13a-Tetrahydrocolumbamine
Geissoschizine <-> Polyneuridine aldehyde
Carbamoyl phosphate + Deacetylcephalosporin C <-> Phosphate + O-Carbamoyl-deacetylcephalosporin C
L-Serine + Indole <-> H2O + L-Tryptophan
O2 + 2-Oxoglutarate + Gibberellin A9 <-> CO2 + Succinate + Gibberellin A4
Tetracenomycin D3 <-> Tetracenomycin B3
NADP+ + (R)-Pantoate <-> H+ + NADPH + 2-Dehydropantoate
S-Adenosyl-L-methionine + Theobromine <-> S-Adenosyl-L-homocysteine + Caffeine
Levopimarinol <-> Levopimarinal
ATP + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine <-> ADP + Phosphate + Aminoimidazole ribotide
ATP + beta-Alanine + (R)-Pantoate <-> Diphosphate + AMP + (R)-Pantothenate
NAD+ + L-Homoserine <-> NADH + H+ + L-Aspartate 4-semialdehyde
9'-cis-Neoxanthin <-> 9-cis-Violaxanthin
Glutaryl-CoA + Electron-transferring flavoprotein <-> CO2 + Crotonoyl-CoA + Reduced electron-transferring flavoprotein
NAD+ + Butanoyl-CoA <-> NADH + H+ + Crotonoyl-CoA
Citrate <-> H2O + cis-Aconitate
H2O + O2 + Dopamine <-> NH3 + H2O2 + 3,4-Dihydroxyphenylacetaldehyde
3 Malonyl-CoA + N-Methylanthraniloyl-CoA <-> H2O + 4 Coenzyme A + 3 CO2 + 1,3-Dihydroxy-N-methyl-acridone
beta-Carotene <-> Echinenone
Naringenin <-> Naringenin chalcone
H2O + L-Asparagine <-> L-Aspartate + NH3
H2O + 2-Succinylbenzoate <-> 2-Succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate
ATP + L-Proline <-> Diphosphate + AMP + L-Prolyl-[pcp]
4,6-Dideoxy-4-oxo-dTDP-D-glucose <-> dTDP-4-oxo-6-deoxy-D-allose
(S)-2,3-Epoxysqualene <-> beta-Amyrin
Geranylgeranyl diphosphate <-> Copalyl diphosphate
Gibberellin A12 aldehyde <-> Gibberellin A14 aldehyde
S-Adenosyl-L-methionine + (S)-Norreticuline <-> S-Adenosyl-L-homocysteine + (S)-Reticuline
Phosphate + alpha,alpha-Trehalose <-> D-Glucose + beta-D-Glucose 1-phosphate
S-Adenosyl-L-methionine + TRIBOA glucoside <-> S-Adenosyl-L-homocysteine + DIMBOA glucoside
O2 + 2-Oxoglutarate + Eriodictyol <-> CO2 + Succinate + Taxifolin
2,7,4'-Trihydroxyisoflavanone <-> H2O + Daidzein
2-Oxoglutarate + N2-Acetyl-L-ornithine <-> L-Glutamate + N-Acetyl-L-glutamate 5-semialdehyde
Tetrangomycin <-> Rabelomycin
O2 + 2-Oxoglutarate + Dihydrokaempferol <-> H2O + CO2 + Succinate + Kaempferol
Coumermycin D + 2 5-Methyl-pyrrole-2-carboxyl-[pcp] <-> Coumermycin A1
Phosphoenolpyruvate + Shikimate 3-phosphate <-> Phosphate + 5-O-(1-Carboxyvinyl)-3-phosphoshikimate
19-Hydroxytabersonine <-> Horhammericine
Phosphatidylserine <-> CO2 + Phosphatidylethanolamine
H+ + NADPH + Crotonoyl-CoA <-> NADP+ + Butanoyl-CoA
S-Adenosyl-L-methionine + N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate <-> S-Adenosyl-L-homocysteine + N-Acetyl-O-demethylpuromycin-5'-phosphate
H2O + O2 + Abscisic aldehyde <-> H2O2 + Abscisate
Levopimarinal <-> L-Pimaric acid
D-Ribose 5-phosphate + Aminofructose 6-phosphate <-> D-Sedoheptulose 7-phosphate + Iminoerythrose 4-phosphate
NAD+ + UDP-D-glucose <-> NADH + H+ + UDP-3-ketoglucose
NAD+ + 2 L-Glutamate <-> NADH + H+ + L-Glutamine + 2-Oxoglutarate
Diphosphate + XMP <-> 5-Phospho-alpha-D-ribose 1-diphosphate + Xanthine
H2O + O2 + Cadaverine <-> NH3 + H2O2 + 5-Aminopentanal
S-Adenosyl-L-methionine + Laricitrin <-> S-Adenosyl-L-homocysteine + Syringetin
ATP + Sulfate <-> Diphosphate + Adenylylsulfate
H+ + NADPH + O2 + Deoxyloganin <-> H2O + NADP+ + Loganin
Acetyl-CoA + Deacetylvindoline <-> Coenzyme A + Vindoline
Urdamycinone B + dTDP-beta-L-rhodinose <-> dTDP + 100-1
S-Adenosyl-L-methionine + 7-Methylxanthine <-> S-Adenosyl-L-homocysteine + Theobromine
S-Adenosyl-L-methionine + 5-Hydroxyferulate <-> S-Adenosyl-L-homocysteine + Sinapate
Copalyl diphosphate <-> Diphosphate + Neoabietadiene
L-Serine + Phosphatidylethanolamine <-> Ethanolamine + Phosphatidylserine
Acetyl-CoA + Fumigaclavine B <-> Coenzyme A + Fumigaclavine A
Oxalosuccinate <-> CO2 + 2-Oxoglutarate
Megalomicin A <-> Megalomicin B
H2O + NADP+ + meso-2,6-Diaminoheptanedioate <-> H+ + NADPH + NH3 + L-2-Amino-6-oxoheptanedioate
Geranyl diphosphate <-> Diphosphate + (-)-Limonene
ATP + Kanosamine <-> ADP + Kanosamine 6-phosphate
O2 + 2 D-Urobilinogen <-> 2 H2O + 2 D-Urobilin
ATP + 1,2-Diacyl-sn-glycerol <-> ADP + 1,2-Diacyl-sn-glycerol 3-phosphate
S-Adenosyl-L-homocysteine + Cephamycin C <-> S-Adenosyl-L-methionine + 7a-Hydroxy-o-carbamoyl-deacetylcephalosporin C
(1,4-alpha-D-Glucosyl)n + ADP alpha-D-glucoside <-> ADP + (1,4-alpha-D-Glucosyl)n
Vinblastine <-> Vincristine
H+ + NADPH + O2 + 8,8a-Deoxyoleandolide <-> H2O + NADP+ + Oleandolide
Glycerate 3-phosphate + NAD+ <-> NADH + H+ + 3-Phosphohydroxypyruvate
L-2-Aminoadipate adenylate + Holo-Lys2 <-> AMP + alpha-Aminoadipoyl-S-acyl enzyme
Gibberellin A9 <-> 2,3-Dehydro-gibberellin A9
H+ + NADPH + O2 + Magnesium protoporphyrin monomethyl ester <-> H2O + NADP+ + 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester
ATP + Coenzyme A + (3R)-3-Isopropenyl-6-oxoheptanoate <-> ADP + Phosphate + H2O + (3R)-3-Isopropenyl-6-oxoheptanoyl-CoA
UDP-D-glucose + D-Fructose 6-phosphate <-> UDP + Sucrose 6-phosphate
Amylose <-> Starch
UDP-D-glucose + 2-Coumarate <-> UDP + trans-beta-D-Glucosyl-2-hydroxycinnamate
H+ + NADPH + O2 + Tabersonine <-> H2O + NADP+ + Lochnericine
(S)-3-Hydroxybutanoyl-CoA <-> H2O + Crotonoyl-CoA
Pyruvate + L-Phenylalanine <-> L-Alanine + Phenylpyruvate
3'-Phosphoadenylyl sulfate + Desulfoglucotropeolin <-> Adenosine 3',5'-bisphosphate + Glucotropeolin
NAD+ + Reduced FMN <-> NADH + H+ + Riboflavin-5-phosphate
S-Adenosyl-L-methionine + (-)-Jasmonic acid <-> S-Adenosyl-L-homocysteine + Methyl jasmonate
H2O + 2,3,4,5-Tetrahydropyridine-2-carboxylate <-> L-2-Aminoadipate 6-semialdehyde
UDPglucose + Cyanidin <-> UDP + Cyanidin 3-O-glucoside
13-Deoxydaunorubicin <-> 13-Dihydrodaunorubicin
3-(4-Hydroxyphenyl)pyruvate <-> CO2 + 4-Hydroxyphenylacetaldehyde
ATP + Glucose <-> ADP + Glucose 6-phosphate
H2O + Feruloyl-CoA <-> 4-Hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA
NAD+ + (-)-Shikimate <-> NADH + H+ + (-)-3-Dehydroshikimate
H2O + D-Glucono-1,5-lactone <-> D-Gluconate
NADP+ + 14-Demethyllanosterol <-> H+ + NADPH + 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
beta-D-Fructose 1,6-bisphosphate <-> D-Glyceraldehyde 3-phosphate + Glycerone phosphate
NAD+ + H2O + Geranial <-> NADH + H+ + (2E)-3,7-Dimethylocta-2,6-dienoic acid
L-Phenylalanine + 2-Oxoglutarate <-> L-Glutamate + Phenylpyruvate
Gibberellin A19 <-> CO2 + Gibberellin A20
H2O + Sucrose 6-phosphate <-> Phosphate + Sucrose
Acetyl-CoA + Propanoyl-CoA <-> Coenzyme A + 2-Methylacetoacetyl-CoA
CDPethanolamine + 1,2-Diacyl-sn-glycerol <-> CMP + Phosphatidylethanolamine
(S)-2,3-Epoxysqualene <-> Cycloartenol
dTDP-4-dehydro-6-deoxy-D-glucose <-> dTDP-4-dehydro-beta-L-rhamnose
ATP + L-2-Aminoadipate <-> Diphosphate + L-2-Aminoadipate adenylate
L-Homocysteine + 5-Methyltetrahydropteroyltri-L-glutamate <-> L-Methionine + Tetrahydropteroyltri-L-glutamate
epsilon-Rhodomycinone + dTDP-beta-L-daunosamine <-> dTDP + Rhodomycin D
NADP+ + beta-D-Glucose 6-phosphate <-> H+ + NADPH + 6-Phospho-D-glucono-1,5-lactone
Geranyl diphosphate <-> Diphosphate + (+)-Limonene
L-Malate + 1-O-Sinapoyl-beta-D-glucose <-> D-Glucose + Sinapoyl-(S)-malate
Dimethylallyl diphosphate + 3-(4-Hydroxyphenyl)pyruvate <-> Diphosphate + 3-Dimethylallyl-4-hydroxyphenylpyruvate
NAD+ + Xanthoxin <-> NADH + H+ + Abscisic aldehyde
H+ + NADPH + 1-Hydroxy-2-methyl-2-butenyl 4-diphosphate <-> H2O + NADP+ + Isopentenyl diphosphate
NADP+ + 8-[(1R,2R)-3-Oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate <-> H+ + NADPH + (15Z)-12-Oxophyto-10,15-dienoate
Isochorismate <-> Pyruvate + Salicylate
D-Glyceraldehyde 3-phosphate + Phosphate + NAD+ <-> NADH + H+ + 3-Phospho-D-glyceroyl phosphate
beta-Hydroxy-L-tyrosyl-[pcp] <-> 3-Dimethylallyl-beta-hydroxy-L-tyrosyl-[pcp]
NADP+ + Isocitrate <-> H+ + NADPH + Oxalosuccinate
2 6,7-Dimethyl-8-(1-D-ribityl)lumazine <-> Riboflavin + 4-(1-D-Ribitylamino)-5-amino-2,6-dihydroxypyrimidine
Tetracenomycin F2 <-> Tetracenomycin F1
H+ + NADPH + O2 + 5-O-beta-D-Mycaminosyltylactone <-> H2O + NADP+ + 5-O-beta-D-Mycaminosyltylonolide
(3R)-6-Hydroxy-3-isopropenyl-heptanoate <-> (3R)-3-Isopropenyl-6-oxoheptanoate
H+ + NADPH + O2 + Dihydrochelirubine <-> H2O + NADP+ + 12-Hydroxydihydrochelirubine
S-Adenosyl-L-methionine + (R)-Reticuline <-> S-Adenosyl-L-homocysteine + Laudanine
4,21-Dehydrocorynantheine aldehyde <-> 4,21-Dehydrogeissoschizine
H+ + NADPH + O2 + (-)-Limonene <-> H2O + NADP+ + (-)-trans-Carveol
H+ + NADPH + Acetyl-CoA + 3 Malonyl-CoA <-> H2O + NADP+ + 4 Coenzyme A + 3 CO2 + 6-Methylsalicylate
L-Isoleucine + 2-Oxoglutarate <-> L-Glutamate + (S)-3-Methyl-2-oxopentanoate
4,21-Dehydrogeissoschizine <-> Stemmadenine
dTDP + 3-O-Mycarosylerythronolide B <-> dTDP-beta-L-mycarose + Erythronolide B
AMP + NTP <-> ADP + NDP
dTDP-D-mycaminose + Tylactone <-> dTDP + 5-O-beta-D-Mycaminosyltylactone
H+ + NADPH + O2 + (-)-Limonene <-> H2O + NADP+ + (-)-trans-Isopiperitenol
(R)-2,3-Dihydroxy-3-methylbutanoate <-> H2O + alpha-Ketovaline
NAD+ + L-Arogenate <-> NADH + H+ + L-Tyrosine + CO2
NADP+ + 2'-Hydroxydihydrodaidzein <-> H+ + NADPH + 2'-Hydroxydaidzein
Coenzyme A + 2-Isopropylmalate <-> H2O + Acetyl-CoA + alpha-Ketovaline
beta-D-Glucose 6-phosphate <-> beta-D-Fructose 6-phosphate
Acyl-CoA + 2-Acyl-sn-glycerol 3-phosphate <-> Coenzyme A + 1,2-Diacyl-sn-glycerol 3-phosphate
H2O + Acceptor + N6-(delta2-Isopentenyl)-adenine <-> Adenine + Reduced acceptor + 3-Methylbut-2-enal
L-Ornithine <-> L-Proline + NH3
UDPglucose + Coniferyl alcohol <-> UDP + Coniferin
ATP + Coenzyme A + 3,4-Dihydroxy-trans-cinnamate <-> Diphosphate + AMP + Caffeoyl-CoA
Geranylgeranyl diphosphate <-> Cembrene
Novobiocic acid + dTDP-5-dimethyl-L-lyxose <-> dTDP + Desmethyldescarbamoylnovobiocin
H2O + Spheroidene <-> Hydroxyspheroidene
UDP-D-glucose + Kaempferol 3-O-glucoside <-> UDP + Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside
L-Aspartate <-> CO2 + beta-Alanine
Amylose <-> 1-alpha-D-{(1,4)-alpha-D-Glucosyl}(n-1)-alpha-D-glucopyranoside
NADP+ + 5,6,8,14-Tetradehydro-3,6-dimethoxy-17-methyl-morphinan-4,7-diol <-> H+ + NADPH + Salutaridine
AminoDAHP <-> Phosphate + AminoDHQ
dTDP-L-oleandrose + Avermectin B1b monosaccharide <-> dTDP + Avermectin B1b
D-Glucose 1-phosphate + dTTP <-> Diphosphate + dTDPglucose
UDPglucose + Vomilenine <-> UDP + Raucaffricine
cis-2-Hydroxy cinnamate <-> H2O + Coumarin
Malonyl-CoA + Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside <-> Coenzyme A + 4'''-Demalonylsalvianin
Pyruvate + NAD+ + Coenzyme A <-> NADH + H+ + CO2 + Acetyl-CoA
dTDP-L-mycarose + Demethyllactenocin <-> dTDP + Demethylmacrocin
L-Serine <-> Pyruvate + NH3
4-(1-D-Ribitylamino)-5-amino-2,6-dihydroxypyrimidine + 3,4-Dihydroxy-2-butanone 4-phosphate <-> Phosphate + 2 H2O + 6,7-Dimethyl-8-(1-D-ribityl)lumazine
trans,trans-Farnesyl diphosphate <-> Diphosphate + (+)-delta-Cadinene
ATP + Coenzyme A + 5-Hydroxyferulate <-> Diphosphate + AMP + 5-Hydroxyferuloyl-CoA
2-Oxoglutarate + Isochorismate <-> CO2 + 5-Enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate
L-Glutamine + 2,4,6/3,5-Pentahydroxycyclohexanone <-> 2-Oxoglutaramate + 1-Amino-1-deoxy-scyllo-inositol
2-Phosphoglycerate <-> Glycerate 3-phosphate
S-Adenosyl-L-methionine + Genistein <-> S-Adenosyl-L-homocysteine + Biochanin A
H+ + NADPH + O2 + trans-5-O-(4-Coumaroyl)-D-quinate <-> H2O + NADP+ + trans-5-O-caffeoyl-D-quinate
O2 + 2-Oxoglutarate + Naringenin <-> CO2 + Succinate + Dihydrokaempferol
H2O + Trehalose 6-phosphate <-> Phosphate + alpha,alpha-Trehalose
Pyruvate + 2-Oxobutyrate <-> CO2 + (S)-2-Aceto-2-hydroxybutanoate
dTDP-L-oleandrose + Avermectin B1b aglycone <-> dTDP + Avermectin B1b monosaccharide
L-2-Amino-6-oxoheptanedioate <-> H2O + 2,3,4,5-Tetrahydrodipicolinate
Gibberellin A12 <-> Gibberellin A14
D-Glucose 1-phosphate <-> alpha-D-Glucose 6-phosphate
NAD+ + H2O + Coniferaldehyde <-> NADH + H+ + Ferulate
H2O + L-Cystathionine <-> Pyruvate + NH3 + L-Homocysteine
UDP-D-xylose + Zeatin <-> UDP + O-beta-D-Xylosylzeatin
3'-Keto-3'-deoxy-ATP <-> Diphosphate + 3'-Keto-3'-deoxy-AMP
H+ + NADPH + O2 + 5alpha-Cholest-7-en-3beta-ol <-> 2 H2O + NADP+ + Cholesta-5,7-dien-3beta-ol
H2O + N6-Acetyl-LL-2,6-diaminoheptanedioate <-> Acetate + LL-2,6-Diaminoheptanedioate
ATP + 3-Amino-4,7-dihydroxy-8-methylcoumarin + 3-Methylpyrrole-2,4-dicarboxylic acid <-> Diphosphate + AMP + Coumeroic acid
Lycopene <-> gamma-Carotene
D-Sedoheptulose 7-phosphate + Glyceraldehyde 3-phosphate <-> D-Ribose 5-phosphate + D-Xylulose 5-phosphate
ADP + D-Glucose <-> AMP + Glucose 6-phosphate
ATP + 3-Amino-4,7-dihydroxy-8-methylcoumarin + Coumeroic acid <-> Diphosphate + AMP + Coumermic acid
Pulegone <-> (-)-Menthone
ITP + Oxaloacetate <-> Phosphoenolpyruvate + CO2 + IDP
ATP + (R)-5-Phosphomevalonate <-> ADP + (R)-5-Diphosphomevalonate
1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide <-> H2O + IMP
ATP + (R)-Mevalonate <-> ADP + (R)-5-Phosphomevalonate
10-Deoxygeniposidic acid <-> Geniposidic acid
Glucose 6-phosphate <-> D-Fructose 6-phosphate
L-Dopa <-> CO2 + Dopamine
ATP + N-Acetyl-L-glutamate <-> ADP + N-Acetyl-L-glutamyl 5-phosphate
H+ + NADPH + Leucocyanidin <-> H2O + NADP+ + (+)-Catechin
Riboflavin-5-phosphate + (S)-4-Hydroxymandelate <-> Reduced FMN + 4-Hydroxyphenylglyoxylate
Malonyl-CoA + Cyanidin 3-O-(6-O-p-coumaroyl)glucoside-5-O-glucoside <-> Coenzyme A + Malonylshisonin
O2 + 3-Dimethylallyl-4-hydroxyphenylpyruvate <-> CO2 + 3-Dimethylallyl-4-hydroxymandelic acid
5 Isopentenyl diphosphate + trans,trans-Farnesyl diphosphate <-> 5 Diphosphate + all-trans-Octaprenyl diphosphate
UDP-kanosamine <-> Kanosamine
Cl- + H+ + L-Tryptophan + O2 + FADH2 <-> 2 H2O + FAD + 7-Chloro-L-tryptophan
Tetracenomycin B3 <-> Tetracenomycin B2
5-O-(1-Carboxyvinyl)-3-phosphoshikimate <-> Phosphate + Chorismate
Violaxanthin <-> Neoxanthin
H2O + CDP-1,2-diacylglycerol <-> CMP + 1,2-Diacyl-sn-glycerol 3-phosphate
trans-beta-D-Glucosyl-2-hydroxycinnamate <-> cis-beta-D-Glucosyl-2-hydroxycinnamate
UDPglucose + Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside <-> UDP + Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside
ATP + H2O + L-Aspartate + L-Glutamine <-> L-Asparagine + L-Glutamate + Diphosphate + AMP
Uroporphyrinogen I <-> 4 CO2 + Coproporphyrinogen I
ATP + D-Glucose <-> ADP + Glucose 6-phosphate
H2O + UDP-D-glucose <-> alpha-D-Glucose 1-phosphate + UMP
meso-2,6-Diaminoheptanedioate <-> L-Lysine + CO2
S-Adenosyl-L-methionine + Zymosterol <-> S-Adenosyl-L-homocysteine + 24-Methylene-5alpha-cholest-8-en-3beta-ol
ATP + Coenzyme A + Succinate <-> ADP + Phosphate + Succinyl-CoA
H2O + 5-Amino-6-(5'-phosphoribitylamino)uracil <-> Phosphate + 4-(1-D-Ribitylamino)-5-amino-2,6-dihydroxypyrimidine
L-Glutamate + Acetyl-CoA <-> Coenzyme A + N-Acetyl-L-glutamate
Acceptor + Coproporphyrinogen I <-> 6 H+ + Reduced acceptor + Coproporphyrin I
NAD+ + H2O + L-Tyrosine <-> NADH + H+ + NH3 + 3-(4-Hydroxyphenyl)pyruvate
UDP + Linamarin <-> UDP-D-glucose + Acetone cyanohydrin
ATP + Coenzyme A + Ferulate <-> Diphosphate + AMP + Feruloyl-CoA
O2 + 2-Oxoglutarate + Desacetoxyvindoline <-> CO2 + Succinate + Deacetylvindoline
NAD+ + H2O + L-Phenylalanine <-> NADH + H+ + NH3 + Phenylpyruvate
ATP + Coenzyme A + Acetate <-> Diphosphate + AMP + Acetyl-CoA
2 L-Tyrosine + O2 <-> 2 L-Dopa
NAD+ + H2O + Citral <-> NADH + H+ + 3,7-Dimethylocta-2,6-dienoic acid
2 L-Isoleucine + Retronecine <-> Senecionine
H+ + NADPH + O2 + 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester <-> 2 H2O + NADP+ + Divinylprotochlorophyllide
S-Adenosyl-L-methionine + Columbamine <-> S-Adenosyl-L-homocysteine + Palmatine
L-Glutamate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate <-> L-Glutamine + N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide
(S)-2-Acetolactate <-> 3-Hydroxy-3-methyl-2-oxobutanoate
2-Isopropylmalate <-> H2O + 2-Isopropylmaleate
UDPxylose + Zeatin <-> UDP + O-beta-D-Xylosylzeatin
O2 + 2-Oxoglutarate + cis-3,4-Leucopelargonidin <-> 2 H2O + CO2 + Succinate + Pelargonidin
CO2 + Anabasine <-> Nicotinate + Piperideine
O2 + 2-Oxoglutarate + Proclavaminic acid <-> 2 H2O + CO2 + Succinate + Dihydroclavaminic acid
NAD+ + (S)-3-Hydroxybutanoyl-CoA <-> NADH + H+ + Acetoacetyl-CoA
UDP-3-ketoglucose <-> UDP-kanosamine
H2O + Phosphoribosyl-AMP <-> 5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide
NADP+ + Leucocyanidin <-> H+ + NADPH + Taxifolin
NADP+ + 1,2-Dihydrovomilenine <-> H+ + NADPH + Vomilenine
2 UDPglucuronate + Bilirubin <-> 2 UDP + Bilirubin beta-diglucuronide
H2O + Penicillin <-> Penicilloic acid
Copalyl diphosphate <-> Diphosphate + Levopimaradiene
13-Dihydrodaunorubicin <-> Daunorubicin
UDP-D-glucose + Pelargonidin <-> UDP + Pelargonidin 3-O-glucoside
H+ + NADPH + O2 + Dihydrosanguinarine <-> H2O + NADP+ + 10-Hydroxydihydrosanguinarine
S-Adenosyl-L-methionine + Phosphatidylethanolamine <-> S-Adenosyl-L-homocysteine + Phosphatidyl-N-methylethanolamine
H+ + NADPH + O2 + 4-Coumaroylshikimate <-> H2O + NADP+ + 5-O-Caffeoylshikimic acid
Rifamycin <-> Rifamycin S
4-Hydroxycinnamyl aldehyde <-> Caffeic aldehyde
Hydrogen sulfide + O-Acetyl-L-serine <-> L-Cysteine + Acetate
UDPglucose + Pelargonidin <-> UDP + Pelargonidin 3-O-glucoside
Acetyl-CoA + Phosphinothricin <-> Coenzyme A + N-Acetylphosphinothricin
4-Hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA <-> Acetyl-CoA + 4-Hydroxy-3-methoxy-benzaldehyde
D-Glyceraldehyde 3-phosphate <-> Glycerone phosphate
NADP+ + L-Arogenate <-> H+ + L-Tyrosine + NADPH + CO2
2 H2O + NADP+ + (S)-Cheilanthifoline <-> H+ + NADPH + O2 + (S)-Scoulerine
NADP+ + 17-O-Acetylnorajmaline <-> H+ + NADPH + 1,2-Dihydrovomilenine
Taxa-4(20),11(12)-dien-5alpha,13alpha-diol <-> 10-Deacetyl-2-debenzoylbaccatin III
L-Tryptophan <-> CO2 + Tryptamine
L-Asparagine <-> H2O + 3-Cyano-L-alanine
O2 + Dopaxanthin <-> 2 H2O + Dopaxanthinquinone
O2 + (S)-Reticuline <-> H2O2 + (S)-Scoulerine
NAD+ + (+)-Borneol <-> NADH + H+ + (+)-Camphor
ATP + Hydrogencarbonate + Propanoyl-CoA <-> ADP + Phosphate + (S)-2-Methyl-3-oxopropanoyl-CoA
L-Glutamine + Chorismate <-> Pyruvate + L-Glutamate + Anthranilate
Phosphate + NADP+ + N-Acetyl-L-glutamate 5-semialdehyde <-> H+ + NADPH + N-Acetyl-L-glutamyl 5-phosphate
H+ + NADPH + O2 + Protopine <-> H2O + NADP+ + 6-Hydroxyprotopine
NADP+ + Phenyllactate <-> H+ + NADPH + Phenylpyruvate
H2O + N1-(5-Phospho-D-ribosyl)-AMP <-> 5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide
H2O + trans,trans-Farnesyl diphosphate <-> Diphosphate + (1E,4S,5E,7R)-Germacra-1(10),5-dien-11-ol
2,3-Dihydroxy-3-methylbutanoate <-> H2O + alpha-Ketovaline
NADP+ + sn-Glycerol 1-phosphate <-> Glycerone phosphate + H+ + NADPH
H+ + NADPH + 5-Hydroxyconiferaldehyde <-> NADP+ + 5-Hydroxyconiferyl alcohol
H2O + Glucose 6-phosphate <-> Phosphate + Glucose
H2O + Sucrose <-> D-Glucose + D-Fructose
D-Fructose + UDPglucose <-> UDP + Sucrose
S-Adenosyl-L-methionine + (S)-Norlaudanosoline <-> S-Adenosyl-L-homocysteine + 6-O-Methylnorlaudanosoline
NADP+ + Coenzyme A + Long-chain aldehyde <-> H+ + NADPH + Long-chain acyl-CoA
NADP+ + (4R)-Ipsdienol <-> H+ + NADPH + Ipsdienone
O-Acetyl-L-serine + Sulfide <-> L-Cysteine + Acetate
H+ + NADPH + Leucodelphinidin <-> H2O + NADP+ + (+)-Gallocatechin
dTDP-L-oleandrose + Avermectin B1a aglycone <-> dTDP + Avermectin B1a monosaccharide
Chorismate <-> Isochorismate
ATP + alpha-D-Glucose <-> alpha-D-Glucose 6-phosphate + ADP
Rifamycin W <-> Rifamycin Z
2-Oxoglutarate + L-2-Aminoadipate <-> L-Glutamate + 2-Oxoadipate
O2 + 2-Oxoglutarate + Gibberellin A53 <-> CO2 + Succinate + Gibberellin A44 diacid
H+ + NADPH + O2 + trans-Cinnamate <-> H2O + NADP+ + 2-Hydroxycinnamate
Glycine + 2 Acceptor <-> CO2 + Cyanide + 2 Reduced acceptor
UTP + alpha-D-Glucose 1-phosphate <-> Diphosphate + UDP-D-glucose
NADP+ + (-)-Menthol <-> H+ + NADPH + (-)-Menthone
H+ + NADPH + O2 + 7-Deoxyloganate <-> H2O + NADP+ + Loganate
UDP-D-glucose + Amylose <-> UDP + Amylose
2 H2O + NADP+ + Stylopine <-> H+ + NADPH + O2 + (S)-Cheilanthifoline
D-Glucose + Acceptor <-> D-Glucono-1,5-lactone + Reduced acceptor
NADP+ + 5-Amino-6-(5'-phosphoribitylamino)uracil <-> H+ + NADPH + 5-Amino-6-(5'-phosphoribosylamino)uracil
all-trans-Nonaprenyl diphosphate + 4-Hydroxybenzoate <-> Diphosphate + Nonaprenyl-4-hydroxybenzoate
2 H2O + NADP+ + (S)-Canadine <-> H+ + NADPH + O2 + 5,8,13,13a-Tetrahydrocolumbamine
GTP + Oxaloacetate <-> Phosphoenolpyruvate + CO2 + GDP
H2O + (R)-Prunasin <-> D-Glucose + Mandelonitrile
H+ + NADPH + O2 + (-)-Limonene <-> H2O + NADP+ + Perillyl alcohol
S-Adenosyl-L-methionine + 6-Demethylsterigmatocystin <-> S-Adenosyl-L-homocysteine + Sterigmatocystin
S-Adenosyl-L-methionine + Phosphatidyl-N-dimethylethanolamine <-> S-Adenosyl-L-homocysteine + Phosphatidylcholine
UDP-D-glucose + (S)-4-Hydroxymandelonitrile <-> UDP + Dhurrin
L-Tyrosine + O2 + Tetrahydrobiopterin <-> L-Dopa + 4a-Hydroxytetrahydrobiopterin
H2O + Cocaine <-> Benzoate + Ecgonine methyl ester
2 S-Adenosyl-L-methionine + dTDP-3-amino-3,6-dideoxy-D-glucose <-> 2 H+ + 2 S-Adenosyl-L-homocysteine + dTDP-D-mycaminose
Hydroxymethylbilane <-> H2O + Uroporphyrinogen III
3-Dimethylallyl-4-hydroxybenzaldehyde <-> 3-Dimethylallyl-4-hydroxybenzoate
4 Isopentenyl diphosphate + trans,trans-Farnesyl diphosphate <-> 4 Diphosphate + All-trans-Heptaprenyl diphosphate
L-Leucine + 2-Oxoglutarate <-> L-Glutamate + 4-Methyl-2-oxopentanoate
NADP+ + (R)-3-(4-Hydroxyphenyl)lactate <-> H+ + NADPH + 3-(4-Hydroxyphenyl)pyruvate
3-Phosphonopyruvate <-> CO2 + 2-Phosphonoacetaldehyde
2 H+ + L-Tryptophan + 2 NADPH + 2 O2 <-> 3 H2O + 2 NADP+ + CO2 + Indole-3-acetaldoxime
100-2 + dTDP-beta-L-rhodinose <-> dTDP + Urdamycin G
Heme O <-> Heme A
1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole <-> 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + Fumarate
Megalomicin A <-> Megalomicin C2
dTDP-D-desosamine + L-Oleandrosyl-oleandolide <-> dTDP + Oleandomycin
D-Ribulose 5-phosphate <-> D-Xylulose 5-phosphate
NAD+ + H2O + L-Leucine <-> NADH + H+ + NH3 + 4-Methyl-2-oxopentanoate
UDPglucose + Quercetin 3-O-glucoside <-> UDP + Quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside
D-Glyceraldehyde 3-phosphate + Pyruvate <-> CO2 + 1-Deoxy-D-xylulose 5-phosphate
Coenzyme A + 1,2-Diacyl-sn-glycerol 3-phosphate <-> Acyl-CoA + 1-Acyl-sn-glycerol 3-phosphate
O2 + 9'-cis-Neoxanthin <-> Xanthoxin + C25-Allenic-apo-aldehyde
5-Aminopentanal <-> Piperideine
trans,trans-Farnesyl diphosphate <-> Diphosphate + Aristolochene
NADP+ + Prephenate <-> H+ + NADPH + CO2 + 3-(4-Hydroxyphenyl)pyruvate
H+ + NADPH + O2 + 10-Deoxysarpagine <-> H2O + NADP+ + Sarpagine
S-Adenosyl-L-methionine + Quercetin <-> S-Adenosyl-L-homocysteine + 3',4',5,7-Tetrahydroxy-3-methoxyflavone
D-Mannose 6-phosphate <-> D-Mannose 1-phosphate
4,21-Dehydrogeissoschizine <-> 19-epi-Cathenamine
O2 + 2-Oxoglutarate + Pentahydroxyflavanone <-> CO2 + Succinate + (+)-Dihydromyricetin
(S)-DNPA <-> 5-Deoxodihydrokalafungin
O-Acetyl-L-serine + Zeatin <-> Acetate + Lupinate
Reduced ferredoxin + 15,16-Dihydrobiliverdin <-> Oxidized ferredoxin + (3Z)-Phycoerythrobilin
4-Coumaroyl-CoA + Shikimate <-> Coenzyme A + 4-Coumaroylshikimate
S-Adenosyl-L-methionine + gamma-Tocopherol <-> S-Adenosyl-L-homocysteine + alpha-Tocopherol
alpha-D-Glucose 1-phosphate + dTTP <-> Diphosphate + dTDP-D-glucose
Rifamycin W <-> Rifamycin W-hemiacetal
NADP+ + D-Glycerate <-> H+ + NADPH + 3-Hydroxypyruvate
L-Malate + Acceptor <-> Oxaloacetate + Reduced acceptor
NADP+ + 2-trans,6-trans-Farnesol <-> H+ + NADPH + 2-trans,6-trans-Farnesal
Iridotrial <-> Deoxyloganin
13-Dihydrocarminomycin <-> Carminomycin
H+ + NADPH + cis-3,4-Leucopelargonidin <-> H2O + NADP+ + Afzelechin
H2O + 1-Guanidino-1-deoxy-scyllo-inositol 4-phosphate <-> Phosphate + 1-Guanidino-1-deoxy-scyllo-inositol
Morphinone <-> Oripavine
2 O2 + 5,8,13,13a-Tetrahydrocolumbamine <-> 2 H2O2 + Columbamine
S-Adenosyl-L-methionine + Daidzein <-> S-Adenosyl-L-homocysteine + Formononetin
H+ + NADPH + O2 + Daidzein <-> H2O + NADP+ + 2'-Hydroxydaidzein
S-Adenosyl-L-methionine + Stylopine <-> S-Adenosyl-L-homocysteine + (S)-cis-N-Methylstylopine
3-Hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA <-> H2O + 3-(4-Methylpent-3-en-1-yl)-pent-2-enedioyl-CoA
NADP+ + (R)-2,3-Dihydroxy-3-methylpentanoate <-> H+ + NADPH + (R)-3-Hydroxy-3-methyl-2-oxopentanoate
S-Adenosyl-L-methionine + 3',4',5-Trihydroxy-3,7-dimethoxyflavone <-> S-Adenosyl-L-homocysteine + 3',5-Dihydroxy-3,4',7-trimethoxyflavone
LL-2,6-Diaminoheptanedioate <-> meso-2,6-Diaminoheptanedioate
NAD+ + (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA <-> NADH + H+ + 2-Methylacetoacetyl-CoA
ATP + Riboflavin-5-phosphate <-> Diphosphate + FAD
NAD+ + H2O + Acetaldehyde <-> NADH + H+ + Acetate
Daunorubicin <-> (13S)-13-Dihydrodaunorubicin
O2 + 2-Oxoglutarate + (6S)-Hydroxyhyoscyamine <-> H2O + CO2 + Succinate + Scopolamine
S-Adenosyl-L-methionine + Caffeyl alcohol <-> S-Adenosyl-L-homocysteine + Coniferyl alcohol
S-Adenosyl-L-methionine + Phosphatidyl-N-methylethanolamine <-> S-Adenosyl-L-homocysteine + Phosphatidyl-N-dimethylethanolamine
ATP + H2O + L-Glutamine + 5'-Phosphoribosyl-N-formylglycinamide <-> ADP + Phosphate + L-Glutamate + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
Lochnericine <-> Horhammericine
UDPglucose + Scopoletin <-> UDP + Scopolin
H2O + NADP+ + L-2-Aminoadipate 6-semialdehyde <-> H+ + NADPH + L-2-Aminoadipate
Hygrine <-> Tropinone
H+ + NADPH + O2 + Taxa-4(20),11(12)-dien-5alpha-ol <-> H2O + NADP+ + Taxa-4(20),11(12)-dien-5alpha,13alpha-diol
Copalyl diphosphate <-> Diphosphate + Pimaradiene
D-Glucose 6-phosphate <-> D-Fructose 6-phosphate
10-Carboxy-13-deoxycarminomycin <-> CO2 + 13-Deoxycarminomycin
dTDP-D-desosamine + Narbonolide <-> dTDP + Narbomycin
H2O + Phosphatidylethanolamine <-> Ethanolamine + 1,2-Diacyl-sn-glycerol 3-phosphate
dTDP-L-oleandrose + Avermectin A1a monosaccharide <-> dTDP + Avermectin A1a
NADP+ + Divinyl chlorophyllide a <-> H+ + NADPH + Divinylprotochlorophyllide
Nogalonic acid methyl ester <-> Auraviketone
ATP + D-Fructose <-> ADP + D-Fructose 6-phosphate
Reduced acceptor + Uroporphyrinogen I <-> 6 H+ + Acceptor + Uroporphyrin I
Acetyl-CoA + Serotonin <-> Coenzyme A + N-Acetylserotonin
NAD+ + H2O + L-Isoleucine <-> NADH + H+ + NH3 + (S)-3-Methyl-2-oxopentanoate
NADP+ + Geraniol <-> H+ + NADPH + Geranial
3 Malonyl-CoA + 4-Coumaroyl-CoA <-> 4 Coenzyme A + 3 CO2 + Naringenin chalcone
L-Arginine + 1-Amino-1-deoxy-scyllo-inositol 4-phosphate <-> L-Ornithine + 1-Guanidino-1-deoxy-scyllo-inositol 4-phosphate
H+ + NADPH + 2'-Hydroxyformononetin <-> NADP+ + Vestitone
L-Ascorbate + Antheraxanthin <-> H2O + Dehydroascorbate + Zeaxanthin
GTP + D-Mannose 1-phosphate <-> Diphosphate + GDPmannose
NADP+ + Pseudotropine <-> H+ + NADPH + Tropinone
H2O + Geranyl diphosphate <-> Diphosphate + (-)-Linalool
Tabersonine <-> Horhammericine
Geranyl diphosphate <-> Diphosphate + (-)-alpha-Pinene
3-Isopropylmalate <-> H2O + 2-Isopropylmaleate
alpha-D-Glucose 6-phosphate <-> beta-D-Fructose 6-phosphate
dTDPglucose <-> H2O + 4,6-Dideoxy-4-oxo-dTDP-D-glucose
3 Malonyl-CoA + Cinnamoyl-CoA <-> 4 Coenzyme A + 4 CO2 + Pinosylvin
Levopimaradiene <-> Levopimarinol
O2 + 6-Deoxyerythronolide B <-> Erythronolide B
ATP + Riboflavin <-> ADP + Riboflavin-5-phosphate
alpha-D-Glucose 6-phosphate <-> beta-D-Glucose 6-phosphate
dTDP-4-oxo-2,6-dideoxy-D-allose <-> dTDP-4-oxo-2,6-dideoxy-L-mannose
O2 + L-Tyrosyl-[pcp] <-> H2O + beta-Hydroxy-L-tyrosyl-[pcp]
NADP+ + Coenzyme A + Coniferaldehyde <-> H+ + NADPH + Feruloyl-CoA
CO2 + 4-Methyl-2-oxopentanoate <-> 3-Carboxy-4-methyl-2-oxopentanoate
D-Glyceraldehyde 3-phosphate + L-Arginine <-> Phosphate + L-N2-(2-Carboxyethyl)arginine
NAD+ + H2O + N6-(L-1,3-Dicarboxypropyl)-L-lysine <-> NADH + H+ + L-Lysine + 2-Oxoglutarate
Geniposidic acid <-> Asperuloside
2 NAD+ + Coenzyme A + (R)-Mevalonate <-> 2 NADH + H+ + 3-Hydroxy-3-methylglutaryl-CoA
NAD+ + Prephenate <-> NADH + H+ + CO2 + 3-(4-Hydroxyphenyl)pyruvate
S-Adenosyl-L-methionine + Chavicol <-> S-Adenosyl-L-homocysteine + Estragole
NADP+ + Sinapyl alcohol <-> H+ + NADPH + Sinapoyl aldehyde
dTDP-6-deoxy-D-allose + 5-O-beta-D-Mycaminosyltylonolide <-> dTDP + Demethyllactenocin
S-Adenosyl-L-methionine + Desmethyldescarbamoylnovobiocin <-> S-Adenosyl-L-homocysteine + Descarbamoylnovobiocin
ATP + Formate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <-> ADP + Phosphate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
NAD+ + 3-Phospho-D-glycerate <-> NADH + H+ + 3-Phosphohydroxypyruvate
10 H+ + 11 NADPH + S-Adenosyl-L-methionine + Acetyl-CoA + 8 Malonyl-CoA <-> 6 H2O + 11 NADP+ + 9 Coenzyme A + 8 CO2 + S-Adenosyl-L-homocysteine + Dihydromonacolin L
O2 + 2-Oxoglutarate + Leucocyanidin <-> H2O + CO2 + Succinate + Taxifolin
L-Cysteine + O-Succinyl-L-homoserine <-> Succinate + L-Cystathionine
S-Adenosyl-L-methionine + (+)-6a-Hydroxymaackiain <-> S-Adenosyl-L-homocysteine + Pisatin
S-Adenosyl-L-methionine + 24-Methylene lophenol <-> S-Adenosyl-L-homocysteine + 24-Ethylidene lophenol
Clavaminic acid <-> Clavulanate-9-aldehyde
Acetyl-CoA + 16-Epivellosimine <-> Coenzyme A + Vinorine
H2O + 5,10-Methylenetetrahydrofolate + alpha-Ketovaline <-> 5,6,7,8-Tetrahydrofolate + 2-Dehydropantoate
Diphosphate + N-(5-Phospho-D-ribosyl)anthranilate <-> 5-Phospho-alpha-D-ribose 1-diphosphate + Anthranilate
NADP+ + Coenzyme A + Caffeic aldehyde <-> H+ + NADPH + Caffeoyl-CoA
ATP + ADP <-> ATP + ADP
H2O + 2-Phosphoglycolate <-> Phosphate + Glycolate
2 H+ + 2 Reduced ferredoxin + Red chlorophyll catabolite <-> 2 Oxidized ferredoxin + Primary fluorescent chlorophyll catabolite
O2 + L-Ascorbate + 1-Aminocyclopropane-1-carboxylate <-> 2 H2O + CO2 + Cyanide + Ethylene + Dehydroascorbate
O2 + 3,5-Dihydroxyphenylacetyl-CoA <-> Coenzyme A + 3,5-Dihydroxyphenylglyoxylate
H+ + Dialdehyde <-> H2O + 4,21-Dehydrocorynantheine aldehyde
L-Aspartate + 2-Oxoglutarate <-> L-Glutamate + Oxaloacetate
O2 + 2-Oxoglutarate + Dihydroclavaminic acid <-> 2 H2O + CO2 + Succinate + Clavaminic acid
2 S-Adenosyl-L-methionine + Uroporphyrinogen III <-> 2 S-Adenosyl-L-homocysteine + Precorrin 2
L-Histidinol phosphate + 2-Oxoglutarate <-> L-Glutamate + 3-(Imidazol-4-yl)-2-oxopropyl phosphate
NAD+ + H2O + IMP <-> NADH + H+ + XMP
Aquayamycin + dTDP-beta-L-rhodinose <-> dTDP + 100-2
H+ + NADPH + O2 + ent-7alpha-Hydroxykaur-16-en-19-oic acid <-> 2 H2O + NADP+ + Gibberellin A12 aldehyde
UDP-D-glucose + Delphinidin <-> UDP + Delphinidin 3-O-glucoside
Violaxanthin <-> Capsorubin
Pyruvate + 4-Hydroxybenzoate <-> Chorismate
AminoDHS <-> H2O + AHBA
Novclobiocin 104 + 5-Methyl-pyrrole-2-carboxyl-[pcp] <-> Clorobiocin
dTDP-D-glucose <-> H2O + 4,6-Dideoxy-4-oxo-dTDP-D-glucose
Geranylgeranyl diphosphate <-> ent-Copalyl diphosphate
4,6-Dideoxy-4-oxo-dTDP-D-glucose <-> 3,6-Dideoxy-3-oxo-dTDP-D-glucose
NAD+ + Geraniol <-> NADH + H+ + Geranial
NAD+ + Ethanol <-> NADH + H+ + Acetaldehyde
Reduced ferredoxin + Biliverdin <-> Oxidized ferredoxin + (3Z)-Phycocyanobilin
Neoabietadiene <-> Neoabietinol
ATP + L-Aspartate <-> ADP + 4-Phospho-L-aspartate
dTDP-L-olivose + Oleandolide <-> dTDP + L-Olivosyl-oleandolide
Acceptor + (S)-Reticuline <-> Reduced acceptor + 1,2-Dehydroreticuline
Succinate + Ubiquinone <-> Fumarate + Ubiquinol
NAD+ + (+)-trans-Carveol <-> NADH + H+ + (+)-(S)-Carvone
Tetracenomycin B3 <-> Tetracenomycin E
Gibberellin A12 <-> Gibberellin A53
H2O + L-Histidinol phosphate <-> Phosphate + L-Histidinol
D-Glyceraldehyde 3-phosphate + Sedoheptulose 7-phosphate <-> D-Ribose 5-phosphate + D-Xylulose 5-phosphate
UDPglucose + (S)-4-Hydroxymandelonitrile <-> UDP + Dhurrin
Tetrangomycin <-> Tetrangulol
Phosphate + NADP+ + L-Aspartate 4-semialdehyde <-> H+ + NADPH + 4-Phospho-L-aspartate
ATP + D-Glycerate <-> 2-Phospho-D-glycerate + ADP
S-Adenosyl-L-methionine + L-Olivosyl-oleandolide <-> S-Adenosyl-L-homocysteine + L-Oleandrosyl-oleandolide
H2O + Penicillin <-> Carboxylate + 6-Aminopenicillanate
Vindoline + Catharanthine <-> 3',4'-Anhydrovinblastine
2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol <-> CMP + 2-C-Methyl-D-erythritol 2,4-cyclodiphosphate
ATP + Glycine + 5-Phospho-beta-D-ribosylamine <-> ADP + Phosphate + 5'-Phosphoribosylglycinamide
L-Serine + Acetyl-CoA <-> Coenzyme A + O-Acetyl-L-serine
S-Adenosyl-L-methionine + Norajmaline <-> S-Adenosyl-L-homocysteine + Ajmaline
O2 + 2-Oxoglutarate + Gibberellin A44 diacid <-> H2O + CO2 + Succinate + Gibberellin A19
2 5-Aminolevulinate <-> 2 H2O + Porphobilinogen
NAD+ + (R,R)-Butane-2,3-diol <-> NADH + H+ + (R)-Acetoin
NAD+ + Shikimate <-> NADH + H+ + 3-Dehydroshikimate
S-Adenosyl-L-methionine + Avermectin B1a aglycone <-> S-Adenosyl-L-homocysteine + Avermectin A1a aglycone
L-Homocysteine + 5-Methyltetrahydrofolate <-> L-Methionine + 5,6,7,8-Tetrahydrofolate
Neopinone <-> Thebaine
Glucose 1-phosphate <-> Glucose 6-phosphate
H2O + NADP+ + Acetaldehyde <-> H+ + NADPH + Acetate
2-Amino-4,5-dihydroxy-6-one-heptanoate-7-phosphate <-> Phosphate + 2 H2O + 3-Amino-4-hydroxybenzoic acid
ATP + Streptomycin <-> ADP + Streptomycin 6-phosphate
NAD+ + 6-Phospho-D-gluconate <-> NADH + H+ + CO2 + D-Ribulose 5-phosphate
H2O + UDPglucose <-> UMP + D-Glucose 1-phosphate
D-Glucose + (R)-Prunasin <-> H2O + (R)-Amygdalin
L-Serine + (3-Indolyl)-glycerol phosphate <-> H2O + L-Tryptophan + Glyceraldehyde 3-phosphate
Acetyl-CoA + 5,6,8,14-Tetradehydro-3,6-dimethoxy-17-methyl-morphinan-4,7-diol <-> Coenzyme A + 7-O-Acetylsalutaridinol
O2 + sn-Glycerol 3-phosphate <-> Glycerone phosphate + H2O2
Gibberellin A4 <-> Gibberellin A1
beta-D-Fructose 6-phosphate + Diphosphate <-> beta-D-Fructose 1,6-bisphosphate + Phosphate
ATP + D-Glucose <-> ADP + D-Glucose 6-phosphate
D-Glucose 6-phosphate <-> Phosphate + 2-Deoxy-L-scyllo-inosose
3-Dehydroquinate <-> H2O + 3-Dehydroshikimate
NAD+ + Homoisocitrate <-> NADH + H+ + CO2 + 2-Oxoadipate
H2O + XMP <-> Phosphate + Xanthosine
Pulegone <-> (+)-Isomenthone
dTDP-4-dehydro-6-deoxy-D-glucose <-> dTDP-3-oxo-6-deoxy-D-glucose
ATP + Aminoimidazole ribotide + Hydrogencarbonate <-> ADP + Phosphate + 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole
UDP + Linamarin <-> UDPglucose + Acetone cyanohydrin
H2O + (7R)-7-(4-Carboxybutanamido)cephalosporanate <-> Glutarate + 7-Aminocephalosporanic acid
Trachelanthamidine <-> Retronecine
dTDP-L-dihydrostreptose + Streptidine 6-phosphate <-> dTDP + O-1,4-alpha-L-Dihydrostreptosyl-streptidine 6-phosphate
NAD+ + L-Galactose <-> NADH + H+ + L-Galactono-1,4-lactone
O2 + Erythromycin <-> H2O + Erythromycin E
H+ + NADPH + O2 + Naringenin <-> H2O + NADP+ + Eriodictyol
ATP + (R)-5-Diphosphomevalonate <-> ADP + Phosphate + CO2 + Isopentenyl diphosphate
H2O + NADP+ + Coniferaldehyde <-> H+ + NADPH + Ferulate
dTDP-D-desosamine + 10-Deoxymethynolide <-> dTDP + YC-17
Gibberellin A4 <-> Gibberellin A7
NAD+ + erythro-2,3-Butanediol <-> NADH + H+ + (S)-Acetoin
Pyridoxamine phosphate + 3,5-Dihydroxyphenylglyoxylate <-> Pyridoxal phosphate + 3,5-Dihydroxy-phenylglycine
S-Adenosyl-L-methionine + Cycloartenol <-> S-Adenosyl-L-homocysteine + 24-Methylenecycloartanol
Amylose + UDPglucose <-> UDP + Amylose
2-Hydroxy-beta-keto-L-tyrosyl-[pcp] <-> 3-Amino-4,7-dihydroxycoumarin
NAD+ + (-)-trans-Isopiperitenol <-> NADH + H+ + (-)-Isopiperitenone
S-Adenosyl-L-methionine + Macrocin <-> S-Adenosyl-L-homocysteine + Tylosin
N(omega)-(L-Arginino)succinate <-> L-Arginine + Fumarate
ATP + L-Aspartate + 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate <-> ADP + Phosphate + 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
S-Adenosyl-L-methionine + L-Homocysteine <-> L-Methionine + S-Adenosyl-L-homocysteine
H+ + NADPH + O2 + Dihydrokaempferol <-> H2O + NADP+ + Taxifolin
O2 + 2-Oxoglutarate + L-Hyoscyamine <-> CO2 + Succinate + (6S)-Hydroxyhyoscyamine
H2O + Sinapoylcholine <-> Choline + Sinapate
1-Carboxyvinyl carboxyphosphonate <-> CO2 + 3-(Hydrohydroxyphosphoryl)pyruvate
Phosphoenolpyruvate <-> 3-Phosphonopyruvate
Gibberellin A51 <-> Gibberellin A51-catabolite
L-Arogenate <-> H2O + L-Phenylalanine + CO2
beta-D-Glucose + (Phosphate)n <-> beta-D-Glucose 6-phosphate + (Phosphate)n
H+ + NADPH + O2 + Taxa-4(20),11(12)-dien-5alpha-yl acetate <-> H2O + NADP+ + Taxa-4(20),11(12)-dien-5alpha-acetoxy-10beta-ol
H+ + NADPH + O2 + Coniferyl alcohol <-> H2O + NADP+ + 5-Hydroxyconiferyl alcohol
NAD+ + 6-endo-Hydroxycineole <-> NADH + H+ + 6-Oxocineole
Thebaine <-> Oripavine
beta-Hydroxy-L-tyrosyl-[pcp] <-> beta-Keto-L-tyrosyl-[pcp]
Dimethylallyl diphosphate + (6aS,11aS)-3,6a,9-Trihydroxypterocarpan <-> Diphosphate + 4-Dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan
H+ + NADPH + O2 + Squalene <-> H2O + NADP+ + (S)-2,3-Epoxysqualene
S-Adenosyl-L-homocysteine + Erythromycin <-> S-Adenosyl-L-methionine + Erythromycin C
UDP-D-glucose + DIBOA <-> UDP + DIBOA glucoside
ATP + D-Ribose 5-phosphate <-> AMP + 5-Phospho-alpha-D-ribose 1-diphosphate
NADP+ + 6-Phospho-D-gluconate <-> H+ + NADPH + CO2 + D-Ribulose 5-phosphate
NH3 + Chorismate <-> Pyruvate + H2O + Anthranilate
L-Tyrosine + 2-Oxoglutarate <-> L-Glutamate + 3-(4-Hydroxyphenyl)pyruvate
UDP-D-glucose + cis-Zeatin <-> UDP + O-beta-D-Glucopyranosyl-cis-zeatin
ATP + D-Gluconate <-> ADP + 6-Phospho-D-gluconate
ATP + beta-D-Glucose <-> ADP + beta-D-Glucose 6-phosphate
NADP+ + Chlorophyllide a <-> H+ + NADPH + Protochlorophyllide
H2O + Geranyl diphosphate <-> Diphosphate + (-)-endo-Fenchol
NADP+ + Bilirubin <-> H+ + NADPH + Biliverdin
3',4'-Anhydrovinblastine <-> Vinblastine
2 H2O + 3-Cyano-L-alanine <-> L-Aspartate + NH3
O2 + delta(L-2-Aminoadipyl)-L-cysteinyl-D-valine <-> 2 H2O + Isopenicillin N
H+ + NADPH + O2 + Coniferaldehyde <-> H2O + NADP+ + 5-Hydroxyconiferaldehyde
H2O + 4 Porphobilinogen <-> 4 NH3 + Hydroxymethylbilane
Hydroxymethylbilane <-> H2O + Uroporphyrinogen I
34a-Deoxy-rifamycin W <-> Rifamycin W
2 NADP+ + (R)-Canadine <-> 2 H+ + 2 NADPH + Berberine
Phosphate + Xanthosine <-> alpha-D-Ribose 1-phosphate + Xanthine
2-Oxoglutarate + N6-Acetyl-LL-2,6-diaminoheptanedioate <-> L-Glutamate + N-Acetyl-L-2-amino-6-oxopimelate
H2O + ADP alpha-D-glucoside <-> AMP + alpha-D-Glucose 1-phosphate
H2O + Coenzyme A <-> Adenosine 3',5'-bisphosphate + 4'-Phosphopantetheine
L-Glutamate + 3,6-Dideoxy-3-oxo-dTDP-D-glucose <-> 2-Oxoglutarate + dTDP-3-amino-3,6-dideoxy-D-glucose
NAD+ + D-Glycerate <-> NADH + H+ + 3-Hydroxypyruvate
CO2 + (S)-2-Acetolactate <-> 2 Pyruvate
L-Lysine <-> CO2 + Cadaverine
L-Threonine <-> Glycine + Acetaldehyde
ATP + Coenzyme A + (3R)-3-Isopropenyl-6-oxoheptanoate <-> H2O + Diphosphate + AMP + (3R)-3-Isopropenyl-6-oxoheptanoyl-CoA
2-Phospho-D-glycerate <-> Phosphoenolpyruvate + H2O
H+ + NADPH + O2 + (4R)-Dihydrocarvone <-> H2O + NADP+ + (4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone
3-Amino-4,7-dihydroxycoumarin <-> 3-Amino-4,7-dihydroxy-8-chlorocoumarin
Cyanidin 3-O-(6-O-p-coumaroyl)glucoside <-> Cyanidin 3-O-(6-O-p-coumaroyl)glucoside-5-O-glucoside
H+ + NADPH + O2 + ent-7alpha-Hydroxykaur-16-en-19-oic acid <-> H2O + NADP+ + 6beta,7beta-Dihydroxykaurenoic acid
Geranyl diphosphate <-> (-)-alpha-Terpineol
(4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone <-> (3R)-6-Hydroxy-3-isopropenyl-heptanoate
H2O + L-Glutamate + 2,3,4,5-Tetrahydrodipicolinate <-> 2-Oxoglutarate + LL-2,6-Diaminoheptanedioate
Limonene-1,2-diol <-> (1S,4R)-1-Hydroxy-2-oxolimonene
H2O + Glycine + 5,10-Methylenetetrahydrofolate <-> L-Serine + 5,6,7,8-Tetrahydrofolate
Feruloyl-CoA <-> 5-Hydroxyferuloyl-CoA
O2 + 2-Oxoglutarate + Taxifolin <-> H2O + CO2 + Succinate + Quercetin
GDP-D-mannose <-> GDP-L-galactose
N-Acetyl-O-demethylpuromycin-5'-phosphate <-> N-Acetyl-O-demethylpuromycin
S-Adenosyl-L-methionine + (S)-Norlaudanosoline <-> S-Adenosyl-L-homocysteine + (S)-6-O-Methylnorlaudanosoline
O2 + Reduced acceptor + Taxa-4(5),11(12)-diene <-> H2O + Acceptor + Taxa-4(20),11(12)-dien-5alpha-ol
S-Adenosyl-L-methionine + Caffeate <-> S-Adenosyl-L-homocysteine + Ferulate
Urdamycinone F <-> H2O + Aquayamycin
S-Adenosyl-L-methionine + 3'-Demethylstaurosporine <-> S-Adenosyl-L-homocysteine + Staurosporine
H2O + Phosphatidylethanolamine <-> Ethanolamine phosphate + 1,2-Diacyl-sn-glycerol
UDPglucose + Kaempferol <-> UDP + Kaempferol 3-O-glucoside
Phosphoenolpyruvate + H2O + D-Erythrose 4-phosphate <-> Phosphate + 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate
Prephytoene diphosphate <-> Diphosphate + Phytoene
Prephenate <-> H2O + CO2 + Phenylpyruvate
Succinyl-CoA + L-Homoserine <-> Coenzyme A + O-Succinyl-L-homoserine
H2O + cis-beta-D-Glucosyl-2-hydroxycinnamate <-> D-Glucose + cis-2-Hydroxy cinnamate
H2O + Streptomycin 6-phosphate <-> Phosphate + Streptomycin
S-Adenosyl-L-methionine + Caffeoyl-CoA <-> S-Adenosyl-L-homocysteine + Feruloyl-CoA
O2 + 2-Oxoglutarate + Eriodictyol <-> H2O + CO2 + Succinate + Luteolin
13-Deoxycarminomycin <-> 13-Deoxydaunorubicin
NAD+ + sn-Glycerol 3-phosphate <-> Glycerone phosphate + NADH + H+
FAD + L-Prolyl-[pcp] <-> FADH2 + 2-Pyrroline-2-carboxyl-[pcp]
H2O + 1,4-Dihydroxy-2-naphthoyl-CoA <-> Coenzyme A + 1,4-Dihydroxy-2-naphthoate
O2 + 9-cis-Violaxanthin <-> Xanthoxin + C25-Epoxy-apo-aldehyde
L-Proline + NADP+ <-> H+ + NADPH + (S)-1-Pyrroline-5-carboxylate
O2 + 2-Oxoglutarate + Penicillin N <-> H2O + CO2 + Succinate + Deacetoxycephalosporin C
L-Ornithine + Carbamoyl phosphate <-> Phosphate + L-Citrulline
Gibberellin A24 <-> CO2 + Gibberellin A9
H2O + Lycopene <-> 1-Hydroxylycopene
sn-Glycerol 3-phosphate + Acyl-CoA <-> Coenzyme A + 2-Acyl-sn-glycerol 3-phosphate
H+ + NADPH + O2 + Formononetin <-> H2O + NADP+ + Calycosin
UDP-D-glucose + Quercetin 3-O-glucoside <-> UDP + Quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside
Isoliquiritigenin <-> Liquiritigenin
L-Glutamate + dTDP-3-oxo-4,6-dideoxy-D-glucose <-> dTDP-3-amino-3,4,6-trideoxy-D-glucose + 2-Oxoglutarate
S-Adenosyl-L-methionine + Sterigmatocystin <-> S-Adenosyl-L-homocysteine + 7-O-Methylsterigmatocystin
Pyruvate + L-Valine <-> L-Alanine + alpha-Ketovaline
(S)-2,3-Epoxysqualene <-> Lupeol
UDP-D-glucose + Cyanidin <-> UDP + Cyanidin 3-O-glucoside
L-Glutamate + Diphosphate + 5-Phospho-beta-D-ribosylamine <-> H2O + L-Glutamine + 5-Phospho-alpha-D-ribose 1-diphosphate
O2 + 2-Oxoglutarate + Gibberellin A20 <-> CO2 + Succinate + Gibberellin A1
10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <-> 5,6,7,8-Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
D-Fructose 6-phosphate + UDPglucose <-> UDP + Sucrose 6-phosphate
H2O + 4-Hydroxybenzoyl-CoA <-> Coenzyme A + 4-Hydroxybenzoate
Megalomicin A <-> Megalomicin C1
 Classification
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