Reaction Details



 Reaction ID 2021
 Stochiometric Equation Coenzyme A + 3-Hydroxy-3-methylglutaryl-CoA <-> H2O + Acetyl-CoA + Acetoacetyl-CoA
 Substrates
Coenzyme A
3-Hydroxy-3-methylglutaryl-CoA
 Products
H2O
Acetyl-CoA
Acetoacetyl-CoA
 Enzymes known to
 catalyse this reaction
 (curated information)
EC Number in Organism UniProtKB Link PubMedID
2.3.3.10 Enterococcus faecalis UniProtKB 12107122
2.3.3.10 Enterococcus faecalis UniProtKB 17128980
2.3.3.10 Gallus gallus UniProtKB 11087424
2.3.3.10 Gallus gallus UniProtKB 12743118
2.3.3.10 Gallus gallus UniProtKB 15247244
2.3.3.10 Gallus gallus UniProtKB 8755743
2.3.3.10 Mus musculus UniProtKB 24315375
 Pathways Synthesis and degradation of ketone bodies
Terpenoid backbone biosynthesis
Valine, leucine and isoleucine degradation
Butanoate metabolism
 External Links
 KEGG-Pathway-ID map00072
map900
map280
map00650
 KEGG-Reaction-ID R01978
 MetaNetX-Reaction-ID MNXR145223


View all entries for reaction Coenzyme A + 3-Hydroxy-3-methylglutaryl-CoA <-> H2O + Acetyl-CoA + Acetoacetyl-CoA

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