Pathway Details

 Recommended name Terpenoid backbone biosynthesis
 Alternative names
 Reactions
H+ + NADPH + O2 + Calcidiol <-> H2O + NADP+ + Calcitriol
NADP+ + 2-trans,6-trans-Farnesol <-> H+ + NADPH + 2-trans,6-trans-Farnesal
H+ + NADPH + 1-Hydroxy-2-methyl-2-butenyl 4-diphosphate <-> H2O + NADP+ + Isopentenyl diphosphate
ATP + (R)-5-Diphosphomevalonate <-> ADP + Phosphate + CO2 + Isopentenyl diphosphate
H+ + NADPH + O2 + Lanosterol <-> NADP+ + Formate + 14-Demethyllanosterol
NADP+ + Cholesterol <-> H+ + NADPH + Desmosterol
2 Acetyl-CoA <-> Coenzyme A + Acetoacetyl-CoA
2 trans,trans-Farnesyl diphosphate <-> H+ + Diphosphate + Presqualene diphosphate
NADP+ + 2-C-Methyl-D-erythritol 4-phosphate <-> H+ + NADPH + 1-Deoxy-D-xylulose 5-phosphate
Vitamin K <-> Vitamin K epoxide
Acceptor + Ergosterol <-> 2 H+ + Reduced acceptor + Ergosta-5,7,22,24(28)-tetraen-3beta-ol
Cycloartenol <-> Zymosterol
H+ + Acceptor + Neurosporene <-> Reduced acceptor + beta-Zeacarotene
Zeaxanthin <-> Violaxanthin
2 H+ + 2-C-Methyl-D-erythritol 2,4-cyclodiphosphate <-> H2O + 1-Hydroxy-2-methyl-2-butenyl 4-diphosphate
Ergosterol <-> Vitamin D2
Acceptor + Lycopene <-> Reduced acceptor + Hydrogen + alpha-Carotene
14-Demethyllanosterol <-> 4alpha-Methylcholesta-8-en-3beta-ol
O2 + 5alpha-Cholest-7-en-3beta-ol <-> H2O2 + Cholesta-5,7-dien-3beta-ol
NAD+ + Cholesterol <-> NADH + H+ + Cholesta-5,7-dien-3beta-ol
Acceptor + beta-Carotene <-> H+ + Reduced acceptor + gamma-Carotene
H+ + NADPH + 24,25-Dihydrolanosterol <-> NADP+ + 4alpha-Methylcholesta-8-en-3beta-ol
CTP + 2-C-Methyl-D-erythritol 4-phosphate <-> Diphosphate + 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol
Isopentenyl diphosphate + all-trans-Hexaprenyl diphosphate <-> Diphosphate + All-trans-Heptaprenyl diphosphate
NADH + H+ + Vitamin K <-> NAD+ + Reduced vitamin K
H2O + Oxidized ferredoxin + Calcidiol <-> O2 + Reduced ferredoxin + Vitamin D3
ATP + (R)-5-Phosphomevalonate <-> ADP + (R)-5-Diphosphomevalonate
O2 + Reduced acceptor + Neurosporene <-> 2 H2O + Acceptor + Lycopene
(S)-2,3-Epoxysqualene <-> Cycloartenol
H+ + NADPH + O2 + 5-Cholestene <-> H2O + NADP+ + 5,6beta-Epoxy-5beta-cholestane
H+ + NADPH + O2 + Cholesterol <-> H2O + NADP+ + Cholesterol-5alpha,6beta-epoxide
ATP + (R)-Mevalonate <-> ADP + (R)-5-Phosphomevalonate
Isopentenyl diphosphate + Geranyl diphosphate <-> Diphosphate + trans,trans-Farnesyl diphosphate
2 NADP+ + Coenzyme A + (R)-Mevalonate <-> 2 H+ + 2 NADPH + 3-Hydroxy-3-methylglutaryl-CoA
H+ + NADPH + 5-Cholestene <-> H2O + NADP+ + 5,6beta-Epoxy-5alpha-cholestane
H+ + NADPH + Presqualene diphosphate <-> NADP+ + Diphosphate + Squalene
Vitamin K epoxide + Gla protein <-> Gla protein precursor + Reduced vitamin K
2 Geranylgeranyl diphosphate <-> H+ + Diphosphate + Prephytoene diphosphate
Ubiquinone + Menaquinone <-> Isopentenyl diphosphate + Geranylgeranyl diphosphate + RING
D-Glyceraldehyde 3-phosphate + Pyruvate <-> CO2 + 1-Deoxy-D-xylulose 5-phosphate
(S)-2,3-Epoxysqualene <-> Lanosterol
6 H+ + 6 NADPH + 6 O2 + 14-Demethyllanosterol <-> 8 H2O + 6 NADP+ + 2 CO2 + Zymosterol
poly-cis-Polyprenyl diphosphate + Isopentenyl diphosphate <-> Diphosphate + Rubber particle
Acceptor + Desmosterol <-> Reduced acceptor + 7-Dehydrodesmosterol
Coenzyme A + 3-Hydroxy-3-methylglutaryl-CoA <-> H2O + Acetyl-CoA + Acetoacetyl-CoA
Acceptor + Phytofluene <-> Reduced acceptor + Hydrogen + zeta-Carotene
Isopentenyl diphosphate <-> Dimethylallyl diphosphate
ATP + 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol <-> ADP + 2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol
All-trans-Pentaprenyl diphosphate + Isopentenyl diphosphate <-> Diphosphate + all-trans-Hexaprenyl diphosphate
Phytyl diphosphate + Chlorophyllide <-> Diphosphate + Chlorophylls
Isopentenyl diphosphate + trans,trans-Farnesyl diphosphate <-> Diphosphate + Geranylgeranyl diphosphate
Violaxanthin <-> Abscisate
NADP+ + Cholesterol <-> H+ + NADPH + Cholesta-5,7-dien-3beta-ol
S-Adenosyl-L-methionine + Protein C-terminal S-farnesyl-L-cysteine <-> S-Adenosyl-L-homocysteine + Protein C-terminal S-farnesyl-L-cysteine methyl ester
beta-Carotene <-> Zeaxanthin
Acceptor + beta-Zeacarotene <-> Reduced acceptor + Hydrogen + gamma-Carotene
2 NAD+ + Coenzyme A + Mevalonate <-> 2 NADH + 2 H+ + 3-Hydroxy-3-methylglutaryl-CoA
H+ + NADPH + O2 + Cholesterol <-> H2O + NADP+ + Cholesterol-5beta,6beta-epoxide
H2O + Cholesterol-5alpha,6beta-epoxide <-> 3beta,5alpha,6beta-Cholestanetriol
Diphosphate + alpha-Tocopherol <-> H+ + Phytyl diphosphate + RING
ATP + Mevalonate <-> ADP + Mevalonate 5-phosphate
beta-Carotene <-> Echinenone
2 NAD+ + Coenzyme A + (R)-Mevalonate <-> 2 NADH + H+ + 3-Hydroxy-3-methylglutaryl-CoA
2 S-Adenosyl-L-methionine + Desmosterol <-> 2 S-Adenosyl-L-homocysteine + Phytosterol
5,6beta-Epoxy-5beta-cholestane <-> 5alpha-Cholestan-5,6beta-diol
Reduced acceptor + 7-Dehydrodesmosterol <-> Acceptor + 5alpha-Cholesta-7,24-dien-3beta-ol
2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol <-> CMP + 2-C-Methyl-D-erythritol 2,4-cyclodiphosphate
Lycopene <-> gamma-Carotene
H+ + NADPH + Lanosterol <-> NADP+ + 24,25-Dihydrolanosterol
H2O + Cholesterol-5beta,6beta-epoxide <-> 3beta,5alpha,6beta-Cholestanetriol
Diphosphate + Vitamin K <-> H+ + Phytyl diphosphate + RING
H2O + NADP+ + Dimethylallyl diphosphate <-> H+ + NADPH + 1-Hydroxy-2-methyl-2-butenyl 4-diphosphate
Dimethylallyl diphosphate + Isopentenyl diphosphate <-> Diphosphate + Geranyl diphosphate
H+ + NADPH + Prephytoene diphosphate <-> NADP+ + Diphosphate + cis-Phytoene
Phytoene <-> Hydrogen + Phytofluene
2 H+ + 1-Hydroxy-2-methyl-2-butenyl 4-diphosphate <-> H2O + Isopentenyl diphosphate
Phytofluene <-> zeta-Carotene
5,6beta-Epoxy-5alpha-cholestane <-> 5alpha-Cholestan-5,6beta-diol
zeta-Carotene <-> Hydrogen + Neurosporene
H+ + 3 NADPH + Geranylgeranyl diphosphate <-> 3 NADP+ + Phytyl diphosphate
Cholesta-5,7-dien-3beta-ol <-> Vitamin D3
S-Adenosyl-L-methionine + Desmosterol <-> S-Adenosyl-L-homocysteine + Ergosta-5,7,22,24(28)-tetraen-3beta-ol
4alpha-Methylcholesta-8-en-3beta-ol <-> Methostenol
 Classification
Metabolism of Terpenoids and Polyketides
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