Reaction Details



 Reaction ID 1788
 Stochiometric Equation NAD+ + Coenzyme A + 4-Methyl-2-oxopentanoate <-> NADH + H+ + CO2 + 3-Methylbutanoyl-CoA
 Substrates
Coenzyme A
NAD+
4-Methyl-2-oxopentanoate
 Products
CO2
NADH
3-Methylbutanoyl-CoA
H+
 Enzymes known to
 catalyse this reaction
 (curated information)
EC Number in Organism UniProtKB Link PubMedID
1.2.4.4 Rattus norvegicus UniProtKB 8537366
Complex: 1.2.4.4 / 2.3.1.168 Bos taurus UniProtKB 283398
Complex: 1.2.4.4 / 2.3.1.168 Oryctolagus cuniculus UniProtKB 7142221
Complex: 1.2.4.4 / 2.3.1.168 Rattus norvegicus UniProtKB 658436
Complex: 1.2.4.4 / 2.3.1.168 / 1.8.1.4 Homo sapiens UniProtKB 3593587
Complex: 1.2.4.4 / 2.3.1.168 / 1.8.1.4 Rattus norvegicus UniProtKB 3571202
 Pathways Valine, leucine and isoleucine degradation
 External Links
 KEGG-Pathway-ID map280
 KEGG-Reaction-ID R01651
 MetaNetX-Reaction-ID MNXR102172
 Rhea-Reaction-ID 25177 25178 25180 25179
 MetaCyc-Reaction-ID 2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN


View all entries for reaction NAD+ + Coenzyme A + 4-Methyl-2-oxopentanoate <-> NADH + H+ + CO2 + 3-Methylbutanoyl-CoA

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