Reaction Details

Reaction ID

1505

Stochiometric Equation

L-Serine + L-Homocysteine <-> H2O + L-Cystathionine

Substrates

L-Serine

L-Homocysteine

Products

H2O

L-Cystathionine

Enzymes known to
catalyse this reaction
(curated information)

EC Number	in Organism	UniProtKB Link	PubMedID
4.2.1.22	Aeropyrum pernix	UniProtKB	12644499
4.2.1.22	Homo sapiens	UniProtKB	15520012
4.2.1.22	Homo sapiens	UniProtKB	15581573
4.2.1.22	Homo sapiens	UniProtKB	681363
4.2.1.22	Homo sapiens	UniProtKB	9675031
4.2.1.22	Rattus norvegicus	UniProtKB	5456996
4.2.1.22	Saccharomyces cerevisiae	UniProtKB	14967036

Pathways

Biosynthesis of amino acids
Biosynthesis of secondary metabolites
Cysteine and methionine metabolism
Glycine, Serine and Threonine metabolism
Metabolic pathways

External Links

KEGG-Pathway-ID

map01230
map01110
map00270
map00260
map01100

KEGG-Reaction-ID

R01290

MetaNetX-Reaction-ID

MNXR97019

Rhea-Reaction-ID

10112 10113 10114 10115

MetaCyc-Reaction-ID

CYSTATHIONINE-BETA-SYNTHASE-RXN

View all entries for reaction L-Serine + L-Homocysteine <-> H2O + L-Cystathionine