Pathway Details

 Recommended name Cysteine and methionine metabolism
 Alternative names
 Reactions
L-Cysteine + 2-Oxoglutarate <-> L-Glutamate + 3-Mercaptopyruvate
NADP+ + (2R)-3-Sulfolactate <-> H+ + NADPH + 3-Sulfopyruvate
H2O + N-Formyl-L-methionine <-> L-Methionine + Formate
Phosphate + 5'-Deoxy-5'-(methylthio)adenosine <-> Adenine + 5-Methylthio-D-ribose 1-phosphate
ATP + 5-Methylthio-D-ribose <-> ADP + 5-Methylthio-D-ribose 1-phosphate
L-Glutamate + 4-Methylthio-2-oxobutanoate <-> L-Methionine + 2-Oxoglutarate
Hydrogen sulfide + O-Acetyl-L-serine <-> L-Cysteine + Acetate
ATP + L-Methionine + tRNA(Met) <-> Diphosphate + AMP + L-Methionyl-tRNA(Met)
H2O + L-Cystathionine <-> L-Cysteine + NH3 + 2-Oxobutyrate
NADP+ + L-Homoserine <-> H+ + NADPH + L-Aspartate 4-semialdehyde
H2O + 2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate <-> Phosphate + 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one
NAD+ + 2 L-Cysteine <-> NADH + H+ + L-Cystine
2 Reduced glutathione + Homocystine <-> Oxidized glutathione + 2 L-Homocysteine
H2O + L-Methionine + Oxidized thioredoxin <-> Reduced thioredoxin + L-Methionine S-oxide
H2O + L-Methionine <-> NH3 + 2-Oxobutyrate + Methanethiol
NAD+ + 3-Mercaptolactate <-> NADH + H+ + 3-Mercaptopyruvate
NAD+ + H2O + 3-Sulfino-L-alanine <-> NADH + H+ + NH3 + 3-Sulfinylpyruvate
Sulfate + S-Glutathionyl-L-cysteine <-> Reduced glutathione + S-Sulfo-L-cysteine
H2O + L-Cystathionine <-> Pyruvate + NH3 + L-Homocysteine
L-Cysteine + O2 <-> 3-Sulfino-L-alanine
H+ + Reduced thioredoxin + O-Acetyl-L-serine + Thiosulfate <-> L-Cysteine + Acetate + Oxidized thioredoxin + Sulfite
Phosphate + Diphosphate + S-Adenosyl-L-methionine <-> ATP + H2O + L-Methionine
O2 + L-Ascorbate + 1-Aminocyclopropane-1-carboxylate <-> 2 H2O + CO2 + Cyanide + Ethylene + Dehydroascorbate
NAD+ + (S)-3-Sulfolactate <-> NADH + H+ + 3-Sulfopyruvate
O-Succinyl-L-homoserine + Sulfide <-> Succinate + L-Homocysteine
L-Cysteine + O-Succinyl-L-homoserine <-> Succinate + L-Cystathionine
2,3-Diketo-5-methylthiopentyl-1-phosphate <-> 2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate
S-Ribosyl-L-homocysteine <-> Homocysteine + 4,5-Dihydroxy-2,3-pentanedione
L-Cysteine + O-Acetyl-L-homoserine <-> Acetate + L-Cystathionine
Phosphate + NADP+ + L-Aspartate 4-semialdehyde <-> H+ + NADPH + 4-Phospho-L-aspartate
O-Succinyl-L-homoserine <-> Pyruvate + NH3 + Succinate
Putrescine + S-Adenosylmethioninamine <-> 5'-Deoxy-5'-(methylthio)adenosine + Spermidine
S-Adenosyl-L-methionine + Cytosine (in DNA) <-> S-Adenosyl-L-homocysteine + 5-Methylcytosine (in DNA)
H2O + L-Cystine <-> Pyruvate + NH3 + Thiocysteine
S-Adenosyl-L-methionine <-> 5'-Deoxy-5'-(methylthio)adenosine + 1-Aminocyclopropane-1-carboxylate
Spermidine + S-Adenosylmethioninamine <-> 5'-Deoxy-5'-(methylthio)adenosine + Spermine
NAD+ + (2R)-3-Sulfolactate <-> NADH + H+ + 3-Sulfopyruvate
2-Oxoglutarate + L-Cysteate <-> Glutamate + 3-Sulfopyruvate
O-Acetyl-L-serine + Sulfide <-> L-Cysteine + Acetate
Acetyl-CoA + L-Homoserine <-> Coenzyme A + O-Acetyl-L-homoserine
H2O + O-Succinyl-L-homoserine <-> NH3 + Succinate + 2-Oxobutyrate
Sulfate + L-Cystine <-> L-Cysteine + S-Sulfo-L-cysteine
H2O + S-Adenosyl-L-homocysteine <-> Adenosine + L-Homocysteine
L-Serine + Acetyl-CoA <-> Coenzyme A + O-Acetyl-L-serine
L-Cysteine <-> D-Cysteine
Hydrogen sulfide + O-Phospho-L-serine <-> Phosphate + L-Cysteine
L-Cysteine + NADP+ + Reduced glutathione <-> H+ + NADPH + S-Glutathionyl-L-cysteine
O2 + 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one <-> Formate + 4-Methylthio-2-oxobutanoate
H2O + L-Cysteine <-> Pyruvate + NH3 + Hydrogen sulfide
3-Sulfino-L-alanine <-> L-Alanine + SO2
L-Cysteine + 2 O-Succinyl-L-homoserine <-> Pyruvate + NH3 + 2 Succinate + L-Cystathionine
O2 + 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one <-> Formate + Carbon monoxide + 3-(Methylthio)propionic acid
H2O + 2,3-Diketo-5-methylthiopentyl-1-phosphate <-> Phosphate + 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one
3'-Phosphoadenylyl sulfate + 2-Aminoacrylate <-> Adenosine 3',5'-bisphosphate + L-Cysteate
L-Cysteine + Sulfite <-> Hydrogen sulfide + L-Cysteate
2 Reduced glutathione + L-Cystine <-> 2 L-Cysteine + Oxidized glutathione
H2O + D-Cysteine <-> Pyruvate + NH3 + Hydrogen sulfide
ATP + L-Aspartate <-> ADP + 4-Phospho-L-aspartate
L-Cysteine + 2-Oxoglutarate <-> Glutamate + 3-Mercaptopyruvate
S-Adenosyl-L-methionine + L-Homocysteine <-> L-Methionine + S-Adenosyl-L-homocysteine
ATP + L-Cysteine + tRNA(Cys) <-> Diphosphate + AMP + L-Cysteinyl-tRNA(Cys)
H+ + Reduced thioredoxin + O-Acetyl-L-homoserine + Thiosulfate <-> Acetate + Oxidized thioredoxin + L-Homocysteine + Sulfite
H2O + S-Adenosyl-L-homocysteine <-> Adenine + S-Ribosyl-L-homocysteine
H2O + S-Ribosyl-L-homocysteine <-> D-Ribose + L-Homocysteine
10-Formyltetrahydrofolate + L-Methionyl-tRNA(Met) <-> 5,6,7,8-Tetrahydrofolate + N-Formylmethionyl-tRNA(fMet)
Succinyl-CoA + L-Homoserine <-> Coenzyme A + O-Succinyl-L-homoserine
L-Homocysteine + Betaine <-> L-Methionine + N,N-Dimethylglycine
2-Oxoglutarate + 3-Sulfino-L-alanine <-> Glutamate + 3-Sulfinylpyruvate
L-Serine + L-Homocysteine <-> H2O + L-Cystathionine
L-Homocysteine + 5-Methyltetrahydrofolate <-> L-Methionine + 5,6,7,8-Tetrahydrofolate
O-Acetyl-L-serine + Thiosulfate <-> Acetate + S-Sulfo-L-cysteine
H2O + Aminoacyl-L-methionine <-> L-Methionine
L-Serine <-> H2O + 2-Aminoacrylate
NAD+ + L-Homoserine <-> NADH + H+ + L-Aspartate 4-semialdehyde
Hydrogen sulfide + O-Acetyl-L-homoserine <-> Acetate + L-Homocysteine
L-Homocysteine + 5-Methyltetrahydropteroyltri-L-glutamate <-> L-Methionine + Tetrahydropteroyltri-L-glutamate
3-Sulfinylpyruvate <-> Pyruvate + SO2
H2O + L-Methionine + O2 <-> NH3 + H2O2 + 4-Methylthio-2-oxobutanoate
H2O + 5'-Deoxy-5'-(methylthio)adenosine <-> Adenine + 5-Methylthio-D-ribose
3-Mercaptopyruvate + Sulfite <-> Pyruvate + H2S2O3
 Classification
Amino Acid Metabolism
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