Reaction Details
Reaction ID
695
Stochiometric Equation
NADP+ + 2 Reduced glutathione <-> H+ + NADPH + Oxidized glutathione
Substrates
Reduced glutathione
NADP+
Products
NADPH
Oxidized glutathione
H+
Enzymes known to
catalyse this reaction
(curated information)
EC Number
in Organism
UniProtKB Link
PubMedID
1.8.1.7
Allochromatium vinosum
UniProtKB
237878
1.8.1.7
Bos taurus
UniProtKB
7316181
1.8.1.7
Enterococcus faecalis
UniProtKB
9741094
1.8.1.7
Escherichia coli
UniProtKB
2540822
1.8.1.7
Euglena gracilis
UniProtKB
3109393
1.8.1.7
Homo sapiens
UniProtKB
15792952
1.8.1.7
Mus musculus
UniProtKB
11259642
1.8.1.7
Rattus norvegicus
UniProtKB
237922
1.8.1.7
Rattus norvegicus
UniProtKB
30053395
1.8.1.7
Sus scrofa
UniProtKB
31912
1.8.1.7
Trypanosoma congolense
UniProtKB
1957352
1.8.1.7
Trypanosoma congolense
UniProtKB
2007114
1.8.4.2
Homo sapiens
UniProtKB
14676218
Pathways
Glutathione metabolism
Metabolic pathways
External Links
KEGG-Pathway-ID
map00480
map01100
KEGG-Reaction-ID
R00115
MetaNetX-Reaction-ID
MNXR100098
Rhea-Reaction-ID
11743
11742
11741
11740
Reactome-Reaction-ID
R-CEL-71682
R-DDI-3323079
R-HSA-71682
R-XTR-71682
R-GGA-71682
R-DRE-3323079
R-TGU-3323079
R-MMU-3323079
R-SCE-3323079
R-OSA-71682
R-RNO-3323079
R-RNO-71682
R-ATH-71682
R-SSC-71682
R-BTA-3323079
R-CFA-71682
R-SSC-3323079
R-SPO-3323079
R-TGU-71682
R-SPO-71682
R-SCE-71682
R-PFA-71682
R-XTR-3323079
R-GGA-3323079
R-PFA-3323079
R-DDI-71682
R-CFA-3323079
R-MMU-71682
R-OSA-3323079
R-CEL-3323079
R-DRE-71682
R-HSA-3323079
R-BTA-71682
R-ATH-3323079
MetaCyc-Reaction-ID
GLUTATHIONE-REDUCT-NADPH-RXN
View all entries for reaction NADP+ + 2 Reduced glutathione <-> H+ + NADPH + Oxidized glutathione
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