Reaction Details

Reaction ID

4312

Stochiometric Equation

N-Acetylneuraminate + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <-> H2O + N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N- acetylneuraminyl)-D-galactosyl-D-glucosylceramide

Substrates

D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide

N-Acetylneuraminate

Products

N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N- acetylneuraminyl)-D-galactosyl-D-glucosylceramide

H2O

Enzymes known to
catalyse this reaction
(curated information)

EC Number	in Organism	UniProtKB Link	PubMedID
3.2.1.18	Homo sapiens	UniProtKB	10861246
3.2.1.18	Homo sapiens	UniProtKB	11298736
3.2.1.18	Homo sapiens	UniProtKB	14613940
3.2.1.18	Homo sapiens	UniProtKB	3360767
3.2.1.18	Homo sapiens	UniProtKB	3654592
3.2.1.18	Homo sapiens	UniProtKB	4994328
3.2.1.18	Rattus norvegicus	UniProtKB	4711815

External Links

KEGG-Pathway-ID

KEGG-Reaction-ID

R04650

MetaNetX-Reaction-ID

MNXR148882

Rhea-Reaction-ID

47857 47856 47859 47858

View all entries for reaction N-Acetylneuraminate + D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide <-> H2O + N-Acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N- acetylneuraminyl)-D-galactosyl-D-glucosylceramide