Reaction Details



 Reaction ID 3001
 Stochiometric Equation NAD+ + Coenzyme A + 3-Methyl-2-oxopentanoate <-> NADH + H+ + CO2 + 2-Methylbutanoyl-CoA
 Substrates
NAD+
Coenzyme A
3-Methyl-2-oxopentanoate
 Products
NADH
CO2
2-Methylbutanoyl-CoA
H+
 Enzymes known to
 catalyse this reaction
 (curated information)
EC Number in Organism UniProtKB Link PubMedID
Complex: 1.2.4.4 / 2.3.1.168 Bos taurus UniProtKB 283398
Complex: 1.2.4.4 / 2.3.1.168 Oryctolagus cuniculus UniProtKB 7142221
Complex: 1.2.4.4 / 2.3.1.168 Rattus norvegicus UniProtKB 658436
Complex: 1.2.4.4 / 2.3.1.168 / 1.8.1.4 Homo sapiens UniProtKB 3593587
Complex: 1.2.4.4 / 2.3.1.168 / 1.8.1.4 Rattus norvegicus UniProtKB 3571202
 Pathways Valine, leucine and isoleucine degradation
 External Links
 KEGG-Pathway-ID map280
 KEGG-Reaction-ID R03171
 MetaNetX-Reaction-ID MNXR102174
 Rhea-Reaction-ID 30907 30909 30908 30910
 MetaCyc-Reaction-ID 2KETO-3METHYLVALERATE-RXN


View all entries for reaction NAD+ + Coenzyme A + 3-Methyl-2-oxopentanoate <-> NADH + H+ + CO2 + 2-Methylbutanoyl-CoA

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