Reaction Details

Reaction ID

1883

Stochiometric Equation

H+ + NADPH + 6,7-Dihydrobiopterin <-> NADP+ + Tetrahydrobiopterin

Substrates

H+

NADPH

6,7-Dihydrobiopterin

Products

NADP+

Tetrahydrobiopterin

Enzymes known to
catalyse this reaction
(curated information)

EC Number	in Organism	UniProtKB Link	PubMedID
1.5.1.33	Leishmania major	UniProtKB	7972081
1.5.1.33	Leishmania major	UniProtKB	9153248
1.5.1.33	Leishmania tarentolae	UniProtKB	9153248
1.5.1.33	Trypanosoma brucei	UniProtKB	19527033
1.5.1.33	Trypanosoma brucei brucei	UniProtKB	19748480
1.5.1.33	Trypanosoma brucei brucei	UniProtKB	21275054

Pathways

Folate biosynthesis

MetaNetX-Reaction-ID

MNXR138941