Reaction Details



 Reaction ID 1350
 Stochiometric Equation NAD+ + H2O + L-Leucine <-> NADH + H+ + NH3 + 4-Methyl-2-oxopentanoate
 Substrates
NAD+
H2O
L-Leucine
 Products
NADH
NH3
4-Methyl-2-oxopentanoate
H+
 Enzymes known to
 catalyse this reaction
 (curated information)
EC Number in Organism UniProtKB Link PubMedID
1.4.1.20 Lysinibacillus sphaericus UniProtKB 12234181
1.4.1.20 Lysinibacillus sphaericus UniProtKB 14622249
1.4.1.20 Thermoactinomyces intermedius UniProtKB 8407879
1.4.1.8 Streptomyces fradiae UniProtKB 3269392
 Pathways Nitrogen metabolism
Valine, leucine and isoleucine biosynthesis
Valine, leucine and isoleucine degradation
 External Links
 KEGG-Pathway-ID map00910
map290
map280
 KEGG-Reaction-ID R01088
 MetaNetX-Reaction-ID MNXR101096
 Rhea-Reaction-ID 12220 12223 12221 12222
 MetaCyc-Reaction-ID LEUCINE-DEHYDROGENASE-RXN


View all entries for reaction NAD+ + H2O + L-Leucine <-> NADH + H+ + NH3 + 4-Methyl-2-oxopentanoate

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