Reaction Details



 Reaction ID 12439
 Stochiometric Equation H2O + Irinotecan <-> SN-38 + 1,4'-Bipiperidine-1'-carboxylic acid
 Substrates
Irinotecan
H2O
 Products
1,4'-Bipiperidine-1'-carboxylic acid
SN-38
 Enzymes known to
 catalyse this reaction
 (curated information)
EC Number in Organism UniProtKB Link PubMedID
3.1.1.1 Homo sapiens UniProtKB 10728672
3.1.1.1 Homo sapiens UniProtKB 15100172
3.1.1.1 Sus scrofa UniProtKB 16223870
 Pathways Drug metabolism - other enzymes
 External Links
 KEGG-Pathway-ID map00983
 KEGG-Reaction-ID R08255
 MetaNetX-Reaction-ID MNXR144373


View all entries for reaction H2O + Irinotecan <-> SN-38 + 1,4'-Bipiperidine-1'-carboxylic acid

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