Enzyme Details
EC Classification
2.6.1.7
Enzyme name
(recommended)
kynurenine---oxoglutarate transaminase
Alternative names
L-kynurenine:2-oxoglutarate aminotransferase
kynurenine transaminase (cyclizing)
kynurenine 2-oxoglutarate transaminase
kynurenine aminotransferase
L-kynurenine aminotransferase
Classification
Transferases
Transferring nitrogenous groups
Transaminases (aminotransferases)
Catalyses reactions
2-Oxoglutarate + L-Kynurenine <-> L-Glutamate + 4-(2-Aminophenyl)-2,4-dioxobutanoate
2-Oxoglutarate + 3-Hydroxy-L-kynurenine <-> L-Glutamate + 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
2-Oxobutyrate + Alanine <-> Pyruvate + Aminobutyrate
2-Oxobutyrate + Asparagine <-> Aminobutyrate + Ketoacid
2-Oxobutyrate + Cysteine <-> Aminobutyrate + Ketoacid
2-Oxobutyrate + Glutamine <-> Aminobutyrate + Ketoacid
2-Oxobutyrate + Histidine <-> Aminobutyrate + Ketoacid
2-Oxobutyrate + Leucine <-> Aminobutyrate + Ketoacid
2-Oxobutyrate + Methionine <-> Aminobutyrate + Ketoacid
2-Oxobutyrate + Phenylalanine <-> Aminobutyrate + Ketoacid
2-Oxobutyrate + Serine <-> Aminobutyrate + Ketoacid
2-Oxobutyrate + Tryptophan <-> Aminobutyrate + Ketoacid
2-Oxobutyrate + Tyrosine <-> Aminobutyrate + Ketoacid
2-Oxoadipate + L-Kynurenine <-> L-2-Aminoadipate + 4-(2-Aminophenyl)-2,4-dioxobutanoate
Oxaloacetate + L-Kynurenine <-> L-Aspartate + 4-(2-Aminophenyl)-2,4-dioxobutanoate
2-Oxoglutarate + 3-Hydroxykynurenine <-> L-Glutamate + 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
2-Oxoadipate + 3-Hydroxykynurenine <-> L-2-Aminoadipate + 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
Oxaloacetate + 3-Hydroxykynurenine <-> L-Aspartate + 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
Glyoxylate + L-Kynurenine <-> Glycine + 4-(2-Aminophenyl)-2,4-dioxobutanoate
Glycine + 2-Oxoglutarate <-> L-Glutamate + Glyoxylate
L-Tyrosine + Glyoxylate <-> Glycine + 3-(4-Hydroxyphenyl)pyruvate
L-Tryptophan + Glyoxylate <-> Glycine + Indolepyruvate
L-Leucine + Glyoxylate <-> Glycine + 4-Methyl-2-oxopentanoate
Glyoxylate + 3-Hydroxy-L-kynurenine <-> Glycine + 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
Glyoxylate + Aminobutyrate <-> Glycine + Succinate semialdehyde
L-Alanine + Glyoxylate <-> Pyruvate + Glycine
2-Oxohexanoate + L-Kynurenine <-> Unknown + 4-(2-Aminophenyl)-2,4-dioxobutanoate
Phenylpyruvate + L-Kynurenine <-> Unknown + 4-(2-Aminophenyl)-2,4-dioxobutanoate
L-Kynurenine + 4-Methylthio-2-oxobutanoate <-> Unknown + 4-(2-Aminophenyl)-2,4-dioxobutanoate
3-Mercaptopyruvate + L-Kynurenine <-> Unknown + 4-(2-Aminophenyl)-2,4-dioxobutanoate
L-Kynurenine + Indolepyruvate <-> Unknown + 4-(2-Aminophenyl)-2,4-dioxobutanoate
2-Oxopentanoate + L-Kynurenine <-> Unknown + 4-(2-Aminophenyl)-2,4-dioxobutanoate
L-Kynurenine + 2-Oxoleucine <-> Unknown + 4-(2-Aminophenyl)-2,4-dioxobutanoate
2-Oxobutyrate + L-Kynurenine <-> Unknown + 4-(2-Aminophenyl)-2,4-dioxobutanoate
L-Kynurenine + Hydroxyphenylpyruvate <-> Unknown + 4-(2-Aminophenyl)-2,4-dioxobutanoate
2-Oxoadipate + L-Kynurenine <-> Unknown + 4-(2-Aminophenyl)-2,4-dioxobutanoate
L-Kynurenine + 2-Oxovaline <-> Unknown + 4-(2-Aminophenyl)-2,4-dioxobutanoate
L-Kynurenine + 3-Methyl-2-oxopentanoate <-> Unknown + 4-(2-Aminophenyl)-2,4-dioxobutanoate
Pyruvate + L-Kynurenine <-> L-Alanine + 4-Hydroxy-2-quinolinecarboxylic acid
L-Phenylalanine + Glyoxylate <-> Glycine + Phenylpyruvate
2-Oxoglutarate + L-Kynurenine <-> L-Glutamate + 4-Hydroxy-2-quinolinecarboxylic acid
External links
Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop
View all entries for EC Class:
2.6.1.7
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