Enzyme Details

EC Classification

1.5.1.34

Enzyme name
(recommended)

6,7-dihydropteridine reductase

Alternative names

6,7-dihydropteridine:NAD(P)H oxidoreductase
5,6,7,8-tetrahydropteridine:NAD(P)+ oxidoreductase
DHPR
NAD(P)H:6,7-dihydropteridine oxidoreductase
NADH-dihydropteridine reductase
NADPH-dihydropteridine reductase
NADPH-specific dihydropteridine reductase
dihydropteridine (reduced nicotinamide adenine dinucleotide) reductase
dihydropteridine reductase
dihydropteridine reductase (NADH)
5,6,7,8-tetrahydropteridine:NAD(P)H+ oxidoreductase

Classification

Oxidoreductases

Acting on the CH-NH group of donors

With NAD(+) or NADP(+) as acceptor

Catalyses reactions

NADH + H+ + 6,7-Dihydrobiopterin <-> NAD+ + Tetrahydrobiopterin

H+ + NADPH + 6,7-Dihydrobiopterin <-> NADP+ + Tetrahydrobiopterin

NADH + H+ + 2-Amino-4-hydroxy-6,7-dimethyldihydropteridine <-> NAD+ + 2-Amino-4-hydroxy-6,7-dimethyltetrahydropteridine

H+ + NADPH + 2-Amino-4-hydroxy-6,7-dimethyldihydropteridine <-> NADP+ + 2-Amino-4-hydroxy-6,7-dimethyltetrahydropteridine

H+ + NADPH + Quinonoid 6,7-dimethyl dihydropteridine <-> NADP+ + 6,7-Dimethyl-tetrahydropteridine

NADH + H+ + Quinonoid 6,7-dimethyl dihydropteridine <-> NAD+ + 6,7-Dimethyl-tetrahydropteridine

NADH + H+ + Quinonoid 6,7-dimethyl dihydropterin <-> NAD+ + 6,7-Dimethyl tetrahydropterin

H+ + NADPH + Quinonoid 6,7-dimethyl dihydropterin <-> NADP+ + 6,7-Dimethyl tetrahydropterin

H+ + NADPH + Quinonoid 7,8-dihydropterin <-> NADP+ + Tetrahydropterin

NADH + H+ + Quinonoid 7,8-dihydropterin <-> NAD+ + Tetrahydropterin

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 1.5.1.34