Enzyme Details

EC Classification

3.4.15.1

Enzyme name
(recommended)

peptidyl-dipeptidase A

Alternative names

DCP
dipeptidyl carboxypeptidase I
peptidase P
dipeptide hydrolase (ambiguous)
peptidyl dipeptidase
angiotensin converting enzyme
kininase II
angiotensin I-converting enzyme
carboxycathepsin
dipeptidyl carboxypeptidase
peptidyl dipeptidase I
peptidyl-dipeptide hydrolase
peptidyldipeptide hydrolase
endothelial cell peptidyl dipeptidase
ACE
peptidyl dipeptidase-4
PDH
peptidyl dipeptide hydrolase

Classification

Hydrolases

Acting on peptide bonds (peptide hydrolases)

Peptidyl-dipeptidases

Catalyses reactions

H2O + Angiotensin I <-> Angiotensin II + His-Leu

H2O + Angiotensin I <-> Angiotensin II

H2O + Hip-His-Leu <-> Hippurate + His-Leu

H2O + N-Acetyl-Ser-Asp-Lys-Pro <-> Lys-Pro + N-Acetyl-Ser-Asp

H2O + furanacryloyl-L-Phe-Gly-Gly <-> Gly-Gly + furanacryloyl-L-Phe

H2O + N-Acetyl angiotensin I <-> His-Leu + N-Acetyl angiotensin II

H2O + Hip-His-Leu-NH2 <-> Hippurate + His-Leu-NH2

H2O + Leu-enkephalin <-> Phe-Leu + Tyr-Gly-Gly

H2O + Leu-enkephalinamide <-> Tyr-Gly-Gly + Phe-Leu-NH2

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 3.4.15.1