Enzyme Details

EC Classification

2.8.2.8

Enzyme name
(recommended)

[heparan sulfate]-glucosamine N-sulfotransferase

Alternative names

3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine N-sulfotransferase
heparin N-sulfotransferase
3'-phosphoadenylylsulfate:N-desulfoheparin sulfotransferase
PAPS:N-desulfoheparin sulfotransferase
PAPS:DSH sulfotransferase
N-HSST
N-heparan sulfate sulfotransferase
heparan sulfate N-deacetylase/N-sulfotransferase
heparan sulfate 2-N-sulfotransferase
heparan sulfate N-sulfotransferase
heparan sulfate sulfotransferase
N-desulfoheparin sulfotransferase
desulfoheparin sulfotransferase
3'-phosphoadenylyl-sulfate:N-desulfoheparin N-sulfotransferase
heparitin sulfotransferase
3'-phosphoadenylyl-sulfate:heparitin N-sulfotransferase

Classification

Transferases

Transferring sulfur-containing groups

Sulfotransferases

Catalyses reactions

3'-Phosphoadenylyl sulfate + N-Desulfoheparin <-> Adenosine 3',5'-bisphosphate + Heparin

H2O + Glucuronyl-N-acetylglucosamine <-> Acetate + Glucuronyl-glucosamine

3'-Phosphoadenylyl sulfate + Glucuronyl-glucosamine <-> Adenosine 3',5'-bisphosphate + Glucuronyl-N-sulfoglucosamine

alpha,alpha-Trehalose + 3'-Phosphoadenylyl sulfate <-> Adenosine 3',5'-bisphosphate + Trehalose 2-sulfate

3'-Phosphoadenylyl sulfate + Heparan sulfate <-> Adenosine 3',5'-bisphosphate + N-Sulfoheparan sulfate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 2.8.2.8