Enzyme Details

EC Classification

2.7.1.145

Enzyme name
(recommended)

deoxynucleoside kinase

Alternative names

ATP:deoxynucleoside 5'-phosphotransferase
multispecific deoxynucleoside kinase
ms-dNK
multisubstrate deoxyribonucleoside kinase
multifunctional deoxynucleoside kinase
D. melanogaster deoxynucleoside kinase
Dm-dNK

Classification

Transferases

Transferring phosphorous-containing groups

Phosphotransferases with an alcohol group as acceptor

Catalyses reactions

ATP + Thymidine <-> ADP + dTMP

ATP + Deoxyadenosine <-> ADP + dAMP

ATP + Deoxyguanosine <-> ADP + dGMP

ATP + 2'-Deoxycytidine <-> ADP + dCMP

ATP + 2'-Deoxynucleoside <-> ADP + Deoxynucleoside 5'-phosphate

CTP + Thymidine <-> dTMP + CDP

ATP + Cytarabine <-> ADP + 1-beta-D-Arabinofuranosylcytosine 5'-monophosphate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 2.7.1.145