Enzyme Details

 EC Classification 1.14.16.2
 Enzyme name
(recommended)		 tyrosine 3-monooxygenase
 Alternative names L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)
L-tyrosine hydroxylase
tyrosine 3-hydroxylase
tyrosine hydroxylase
 Classification
Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With reduced pteridine as one donor, and incorporation of one atom of oxygen
 Catalyses reactions
L-Tyrosine + O2 + Tetrahydrobiopterin <-> H2O + 6,7-Dihydrobiopterin + L-Dopa
L-Tyrosine + O2 + Tetrahydrobiopterin <-> L-Dopa + 4a-Hydroxytetrahydrobiopterin
L-Tyrosine + O2 + 6-Methyltetrahydropterin <-> L-Dopa + 4-Hydroxy-6-methyltetrahydropterin
L-Phenylalanine + O2 + 6-Methyltetrahydropterin <-> H2O + L-Tyrosine + 6-Methyldihydropterin
O2 + Tyramine <-> H2O + Dopamine
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 1.14.16.2



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