Reaction Details



 Reaction ID 3231
 Stochiometric Equation H2O + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate <-> 1,2-Diacyl-sn-glycerol + D-myo-Inositol 1,4,5-trisphosphate
 Substrates
H2O
1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
 Products
1,2-Diacyl-sn-glycerol
D-myo-Inositol 1,4,5-trisphosphate
 Enzymes known to
 catalyse this reaction
 (curated information)
EC Number in Organism UniProtKB Link PubMedID
3.1.4.11 Bos taurus UniProtKB 8519600
3.1.4.11 Homo sapiens UniProtKB 10336610
3.1.4.11 Homo sapiens UniProtKB 8519600
3.1.4.11 Mammalia UniProtKB 15709770
3.1.4.11 Oryctolagus cuniculus UniProtKB 214133
3.1.4.11 Rattus norvegicus UniProtKB 15322077
3.1.4.11 Rattus norvegicus UniProtKB 8519600
3.1.4.11 Rattus norvegicus UniProtKB 9565585
 Pathways Inositol phosphate metabolism
Phosphatidylinositol signaling system
 External Links
 KEGG-Pathway-ID map00562
map04070
 KEGG-Reaction-ID R03435
 MetaNetX-Reaction-ID MNXR148157
 Rhea-Reaction-ID 33179 33181 33182 33180
 MetaCyc-Reaction-ID 3.1.4.11-RXN


View all entries for reaction H2O + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate <-> 1,2-Diacyl-sn-glycerol + D-myo-Inositol 1,4,5-trisphosphate

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