Pathway Details

 Recommended name Lipopolysaccharide biosynthesis
 Alternative names
 Reactions
D-Arabinose 5-phosphate <-> D-Ribulose 5-phosphate
Phosphoenolpyruvate + H2O + D-Erythrose 4-phosphate <-> Phosphate + 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate
UDPglucose + Lipopolysaccharide <-> UDP + D-Glucosyllipopolysaccharide
UDP-N-acetyl-D-glucosamine + Lipopolysaccharide <-> UDP + N-Acetyl-D-glucosaminyllipopolysaccharide
Phosphate + 3-Deoxy-D-manno-octulosonate 8-phosphate <-> Phosphoenolpyruvate + H2O + D-Arabinose 5-phosphate
H2O + 3-Deoxy-D-manno-octulosonate 8-phosphate <-> Phosphate + 3-Deoxy-D-manno-octulosonate
CTP + 3-Deoxy-D-manno-octulosonate <-> Diphosphate + CMP-3-deoxy-D-manno-octulosonate
H2O + UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine <-> UMP + 2,3-Bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate
Holo-[acyl-carrier protein] + UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine <-> (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] + UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine
UDP-N-acetyl-D-glucosamine + (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] <-> Holo-[acyl-carrier protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine
H2O + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine <-> Acetate + UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine
2,3-Bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine <-> UDP + 2,3,2',3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta- D-glucosamine 1-phosphate
ATP + 2,3,2',3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta- D-glucosamine 1-phosphate <-> ADP + 2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate
CMP-3-deoxy-D-manno-octulosonate + 2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate <-> CMP + 3-Deoxy-D-manno-octulosonyl-lipid IV(A)
CMP-3-deoxy-D-manno-octulosonate + 3-Deoxy-D-manno-octulosonyl-lipid IV(A) <-> CMP + Di[3-deoxy-D-manno-octulosonyl]-lipid IV(A)
ADP-D-glycero-D-manno-heptose <-> ADP-L-glycero-D-manno-heptose
ATP + D-Glycero-D-manno-heptose 1-phosphate <-> Diphosphate + ADP-D-glycero-D-manno-heptose
Sedoheptulose 7-phosphate <-> D-Glycero-D-manno-heptose 7-phosphate
ATP + D-Glycero-D-manno-heptose 7-phosphate <-> ADP + D-Glycero-D-manno-heptose 1,7-bisphosphate
H2O + D-Glycero-D-manno-heptose 1,7-bisphosphate <-> Phosphate + D-Glycero-D-manno-heptose 1-phosphate
Phosphoenolpyruvate + H2O + 2-Deoxy-D-ribose 5-phosphate <-> Phosphate + 3,5-Dideoxy-D-manno-octulosonate 8-phosphate
Phosphoenolpyruvate + H2O + D-Ribose 5-phosphate <-> Phosphate + 3-Deoxy-D-altro-octulosonate 8-phosphate
Holo-[acyl-carrier protein] + Di[3-deoxy-D-manno-octulosonyl]-lipid A <-> Tetradecanoyl-[acp] + Lauroyl-KDO2-lipid IV(A)
Holo-[acyl-carrier protein] + Lauroyl-KDO2-lipid IV(A) <-> Dodecanoyl-[acyl-carrier protein] + Di[3-deoxy-D-manno-octulosonyl]-lipid IV(A)
UDP-D-glucose + Lipopolysaccharide <-> UDP + D-Glucosyllipopolysaccharide
 Classification
Glycan Biosynthesis and Metabolism
© HITS gGmbH