Pathway Details

 Recommended name Biotin metabolism
 Alternative names
 Reactions
Coenzyme A + Biotinyl-5'-AMP <-> AMP + Biotinyl-CoA
ATP + CO2 + 7,8-Diaminononanoate <-> ADP + Phosphate + Dethiobiotin
8-Amino-7-oxononanoate + S-Adenosylmethioninamine <-> 7,8-Diaminononanoate + S-Adenosyl-3-methylthiopropanal
ATP + Coenzyme A + Pimelate <-> Diphosphate + AMP + 6-Carboxyhexanoyl-CoA
L-Alanine + 6-Carboxyhexanoyl-CoA <-> Coenzyme A + CO2 + 8-Amino-7-oxononanoate
2 S-Adenosyl-L-methionine + Dethiobiotin + Sulfur-(sulfur carrier) + 2 reduced [2Fe-2S] Ferredoxin <-> 2 L-Methionine + Biotin + 2 5'-Deoxyadenosine + 2 oxidized [2Fe-2S] Ferredoxin + (Sulfur carrier)
H2O + N6-D-Biotinyl-L-lysine <-> L-Lysine + Biotin
Biotinyl-5'-AMP + Apo-[carboxylase] <-> AMP + Holo-[carboxylase]
S-Adenosyl-L-methionine + 8-Amino-7-oxononanoate <-> 7,8-Diaminononanoate + S-Adenosyl-4-methylthio-2-oxobutanoate
Sulfur + Dethiobiotin <-> Biotin
Peptide + N6-D-Biotinyl-L-lysine <-> Holo-[carboxylase]
ATP + Biotin <-> Diphosphate + Biotinyl-5'-AMP
 Classification
Metabolism of Cofactors and Vitamins
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