Pathway Details

 Recommended name Degradation of aromatic compounds
 Alternative names
 Reactions
O2 + 4-Methoxybenzoate + Reduced acceptor <-> H2O + Formaldehyde + 4-Hydroxybenzoate + Acceptor
O2 + 3-Vinylcatechol <-> 2-Hydroxy-6-oxoocta-2,4,7-trienoate
O2 + Naphthalene-1,2-diol <-> 2-Hydroxychromene-2-carboxylate
H2O + 2-Hydroxy-6-ketononatrienedioate <-> Fumarate + 2-Hydroxy-2,4-pentadienoate
ATP + Coenzyme A + Benzoyl acetate <-> Diphosphate + AMP + Benzoyl acetyl-CoA
NAD+ + H2O + Benzaldehyde <-> NADH + H+ + Benzoate
NAD+ + 1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate <-> NADH + H+ + CO2 + 2,3-Dihydroxytoluene
4-Hydroxybenzoate <-> CO2 + Phenol
Coenzyme A + Benzoyl acetyl-CoA <-> Acetyl-CoA + Benzoyl-CoA
O2 + 4-Methylcatechol <-> 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde
2-Hydroxy-8-methylchromene-2-carboxylate <-> 2-Hydroxy-3-methylbenzalpyruvate
Naphthyl-2-hydroxymethyl-succinyl CoA <-> 2 H+ + Naphthyl-2-oxomethyl-succinyl-CoA
O2 + 1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene <-> 1,1-Dichloro-2-(dihydroxy-4'-chlorophenyl)-2-(4'-chlorophenyl)ethylene
H+ + NADPH + O2 + Benzoate <-> H2O + NADP+ + 4-Hydroxybenzoate
2-Oxohept-3-enedioate <-> 2-Hydroxyhepta-2,4-dienedioate
NAD+ + Styrene cis-glycol <-> NADH + H+ + 3-Vinylcatechol
NAD+ + cis-2,3-Dihydro-2,3-dihydroxybiphenyl <-> NADH + H+ + Biphenyl-2,3-diol
H+ + NADPH + O2 + Cyclohexanone <-> H2O + NADP+ + 6-Hexanolide
H2O + Cyclohex-1-ene-1-carboxyl-CoA <-> 2-Hydroxycyclohexane-1-carboxyl-CoA
NAD+ + (S)-1-Phenylethanol <-> NADH + H+ + Acetophenone
H2O + 2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate <-> 2-Hydroxymuconate + Catechol
ATP + Coenzyme A + 4-Hydroxybenzoate <-> Diphosphate + AMP + 4-Hydroxybenzoyl-CoA
trans-O-Hydroxybenzylidenepyruvate <-> 2-Hydroxychromene-2-carboxylate
NAD+ + H2O + 3-Hydroxybenzaldehyde <-> NADH + H+ + 3-Hydroxybenzoate
H2O + 2-Hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate <-> 2-Hydroxy-2,4-pentadienoate + Anthranilate
Formate + 2-Hydroxy-2,4-pentadienoate <-> H2O + 2-Hydroxymuconate semialdehyde
H2O + 2-Hydroxy-6-oxo-7-methylocta-2,4-dienoate <-> 2-Hydroxy-2,4-pentadienoate + Isobutanoate
O2 + 2,2',3-Trihydroxybiphenyl <-> 2-Hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate
NAD+ + 4-Sulfobenzyl alcohol <-> NADH + H+ + 4-Sulfobenzaldehyde
(3R)-6-Hydroxy-3-isopropenyl-heptanoate <-> (3R)-3-Isopropenyl-6-oxoheptanoate
(Z)-5-Oxohex-2-enedioate <-> CO2 + 2-Hydroxy-2,4-pentadienoate
H2O + 2-Ketocyclohexane-1-carboxyl-CoA <-> 6-Carboxyhexanoyl-CoA
(1R,2S,4R)-Neo-dihydrocarveol <-> (1R,4R)-Dihydrocarvone
H2O + cis-4-(1'-Hydroxynaphth-2'-yl)-2-oxobut-3-enoate <-> Pyruvate + 1-Hydroxy-2-naphthaldehyde
NAD+ + 3,6-Dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene <-> NADH + H+ + 3,6-Dichlorocatechol
2-Hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate <-> CO2 + 2-Hydroxy-6-oxo-7-methylocta-2,4-dienoate
H2O + 2-Oxo-2,3-dihydrofuran-5-acetate <-> 3-Oxoadipate
H2O + NADP+ + 2-Hydroxy-5-carboxymethylmuconate semialdehyde <-> H+ + NADPH + 5-Carboxymethyl-2-hydroxymuconate
H+ + NADPH + O2 + 2,4-Dichlorophenol <-> H2O + NADP+ + 3,5-Dichlorocatechol
H2O + Naphthyl-2-methylene-succinyl-CoA <-> Naphthyl-2-hydroxymethyl-succinyl CoA
H2O + NADP+ + p-Tolualdehyde <-> H+ + NADPH + Toluate
NAD+ + S-(-)-1-Phenylethanol <-> NADH + H+ + Acetophenone
Fumarate + 2-Methylnaphthalene <-> Naphthyl-2-methyl-succinic acid
NAD+ + cis-4,5-Dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate <-> NADH + H+ + 4,5-Dihydroxyphthalate
2 Electron-transferring flavoprotein + Benzylsuccinyl-CoA <-> 2 Reduced electron-transferring flavoprotein + E-Phenylitaconyl-CoA
O2 + 3,4-Dihydroxyphenylacetate <-> 2-Hydroxy-5-carboxymethylmuconate semialdehyde
H2O + O2 + 2,6-Dichlorohydroquinone <-> HCl + 2-Chloromaleylacetate
NAD+ + 2-Hydroxycyclohexane-1-carboxyl-CoA <-> NADH + H+ + 2-Ketocyclohexane-1-carboxyl-CoA
NAD+ + 6-Hydroxycyclohex-1-enecarbonyl-CoA <-> NADH + H+ + 6-Ketoxycyclohex-1-ene-1-carboxyl-CoA
O2 + 2,2',3-Trihydroxydiphenylether <-> 2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate
O2 + 3,4-Dihydroxybenzoate <-> 3-Carboxy-cis,cis-muconate
NAD+ + 6-Hydroxyhexanoate <-> NADH + H+ + 6-Oxohexanoate
2 H2O + 6-Ketoxycyclohex-1-ene-1-carboxyl-CoA <-> 3-Hydroxypimeloyl-CoA
NAD+ + 3-Methylbenzyl alcohol <-> NADH + H+ + 3-Methylbenzaldehyde
NAD+ + 1,6-Dihydroxy-cis-2,4-cyclohexadiene-1-carboxylic acid <-> NADH + H+ + CO2 + Catechol
2 ATP + 2 H2O + Benzoyl-CoA + Reduced acceptor <-> 2 ADP + 2 Phosphate + Acceptor + S-1,5-Cyclohexadiene-1-carboxylate coenzymeA
Coenzyme A + Naphthyl-2-methyl-succinyl-CoA <-> Succinyl-CoA + 2-Naphthoyl-CoA
5-Carboxymethyl-2-hydroxymuconate <-> 5-Carboxy-2-oxohept-3-enedioate
O2 + 2,3-Dihydroxy-4'-chlorobiphenyl <-> 2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate
Phenylpropanoate <-> 3-(3-Hydroxy-phenyl)-propanoic acid
Coenzyme A + Benzoylsuccinyl-CoA <-> Succinyl-CoA + Benzoyl-CoA
Pyruvate + Acetaldehyde <-> 4-Hydroxy-2-oxopentanoate
2-Hydroxymuconate <-> (Z)-5-Oxohex-2-enedioate
H2O + NADP+ + 2-Methylbenzaldehyde <-> H+ + NADPH + o-Toluate
NAD+ + H2O + 1-Naphthaldehyde <-> NADH + H+ + 1-Naphthoic acid
NAD+ + (2-Naphthyl)methanol <-> NADH + H+ + 2-Naphthaldehyde
ATP + Coenzyme A + (3R)-3-Isopropenyl-6-oxoheptanoate <-> H2O + Diphosphate + AMP + (3R)-3-Isopropenyl-6-oxoheptanoyl-CoA
Fumarate + Toluene <-> Benzylsuccinate
H+ + NADPH + O2 + (4R)-Dihydrocarvone <-> H2O + NADP+ + (4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone
O2 + 3-(2,3-Dihydroxyphenyl)propanoate <-> 2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate
H+ + NADPH + O2 + 4-Hydroxybenzoate <-> H2O + NADP+ + 3,4-Dihydroxybenzoate
NAD+ + alpha-Hydroxy-p-xylene <-> NADH + H+ + p-Tolualdehyde
H2O + 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde <-> Formate + 2-Hydroxy-cis-hex-2,4-dienoate
O2 + trans-2,3-Dihydroxycinnamate <-> 2-Hydroxy-6-ketononatrienedioate
O2 + 2,3-Dihydroxytoluene <-> 2-Hydroxy-6-keto-2,4-heptadienoate
NAD+ + H2O + 1-Hydroxy-2-naphthaldehyde <-> NADH + H+ + 1-Hydroxy-2-naphthoate
NADP+ + cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate <-> H+ + NADPH + CO2 + 4-Methylcatechol
(4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone <-> (3R)-6-Hydroxy-3-isopropenyl-heptanoate
H2O + 2-Hydroxy-3-methylbenzalpyruvate <-> Pyruvate + 3-Methylsalicylaldehyde
O2 + 1,2-Dihydroxy-8-methylnaphthalene <-> 2-Hydroxy-8-methylchromene-2-carboxylate
O2 + 2'-Aminobiphenyl-2,3-diol <-> 2-Hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate
2-Oxo-5-methyl-cis-muconate <-> CO2 + 2-Hydroxy-cis-hex-2,4-dienoate
2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate <-> CO2 + 2-Oxo-2,3-dihydrofuran-5-acetate
H2O + NADP+ + 6-Oxohexanoate <-> H+ + NADPH + Adipate
NAD+ + (Hydroxymethylphenyl)succinyl-CoA <-> NADH + H+ + Benzoylsuccinyl-CoA
H+ + NADPH + O2 + 3-Hydroxybenzoate <-> H2O + NADP+ + 3,4-Dihydroxybenzoate
5-Carboxy-2-oxohept-3-enedioate <-> CO2 + 2-Hydroxyhepta-2,4-dienedioate
H2O + 2-Hydroxy-6-oxoocta-2,4,7-trienoate <-> Acrylate + 2-Hydroxy-2,4-pentadienoate
ATP + Coenzyme A + Adipate <-> Diphosphate + AMP + Adipyl-CoA
CO2 + Acetophenone <-> H+ + Benzoyl acetate
NAD+ + H2O + 3-Methylsalicylaldehyde <-> NADH + H+ + 3-Methylsalicylate
Benzoate <-> 3-Hydroxybenzoate
H2O + 2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoate <-> Benzoate + 2-Hydroxy-2,4-pentadienoate
NAD+ + 1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate <-> NADH + H+ + CO2 + 2,3-Dihydroxytoluene
H2O + S-1,5-Cyclohexadiene-1-carboxylate coenzymeA <-> 6-Hydroxycyclohex-1-enecarbonyl-CoA
NAD+ + Coenzyme A + Acetaldehyde <-> NADH + H+ + Acetyl-CoA
H2O + 6-Hexanolide <-> 6-Hydroxyhexanoate
H2O + 2-Hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate <-> 2-Hydroxy-2,4-pentadienoate + Salicylate
NAD+ + Cyclohexanol <-> NADH + H+ + Cyclohexanone
NAD+ + cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol <-> NADH + H+ + trans-2,3-Dihydroxycinnamate
H2O + 6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7E-trienoate <-> 2-(4'-Chlorophenyl)-3,3-dichloropropenoate + 2-Hydroxy-3-chloropenta-2,4-dienoate
2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate <-> 3-Carboxy-cis,cis-muconate
Pyruvate + Propanal <-> 4-Hydroxy-2-oxohexanoate
NAD+ + cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate <-> NADH + H+ + CO2 + 4-Methylcatechol
O2 + 1,1-Dichloro-2-(dihydroxy-4'-chlorophenyl)-2-(4'-chlorophenyl)ethylene <-> 6-Oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7E-trienoate
H2O + 2-Hydroxy-2,4-pentadienoate <-> 4-Hydroxy-2-oxopentanoate
H+ + NADPH + O2 + trans-Cinnamate <-> H2O + NADP+ + 4-Coumarate
NAD+ + H2O + Salicylaldehyde <-> NADH + H+ + Salicylate
NAD+ + cis-1,2-Dihydroxy-1,2-dihydro-8-methylnaphthalene <-> NADH + H+ + 1,2-Dihydroxy-8-methylnaphthalene
H+ + NADPH + O2 + Toluene <-> H2O + NADP+ + 3-Cresol
NAD+ + H2O + 4-Sulfobenzaldehyde <-> NADH + H+ + 4-Sulfobenzoate
NADH + H+ + O2 + Methane <-> NAD+ + H2O + Methanol
NADP+ + 6-Hydroxyhexanoate <-> H+ + NADPH + 6-Oxohexanoate
NAD+ + H2O + 2-Hydroxy-5-carboxymethylmuconate semialdehyde <-> NADH + H+ + 5-Carboxymethyl-2-hydroxymuconate
H2O + Acceptor + Ethylbenzene <-> Reduced acceptor + (S)-1-Phenylethanol
H+ + NADPH + O2 + Toluene <-> H2O + NADP+ + o-Cresol
2-Hydroxy-5-methyl-cis,cis-muconate <-> 2-Oxo-5-methyl-cis-muconate
trans-Cinnamate <-> trans-3-Hydroxycinnamate
NAD+ + cis-1,2-Dihydro-3-ethylcatechol <-> NADH + H+ + 3-Ethylcatechol
NAD+ + cis-2,3-Dihydro-2,3-dihydroxy-4'-chlorobiphenyl <-> NADH + H+ + 2,3-Dihydroxy-4'-chlorobiphenyl
H2O + 4-Isopropenyl-2-oxy-cyclohexanecarboxyl-CoA <-> 3-Isopropenylpimelyl-CoA
O2 + Phenanthrene-3,4-diol <-> 2-Hydroxy-2H-benzo[h]chromene-2-carboxylate
O2 + 2,3-Dihydroxy-p-cumate <-> 2-Hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate
NAD+ + cis-2,3-Dihydroxy-2,3-dihydro-p-cumate <-> NADH + H+ + 2,3-Dihydroxy-p-cumate
NAD+ + H2O + 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde <-> NADH + H+ + 2-Hydroxy-5-methyl-cis,cis-muconate
H2O + 2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate <-> 2-Hydroxy-2,4-pentadienoate + 4-Chlorobenzoate
NAD+ + 1-Hydroxymethylnaphthalene <-> NADH + H+ + 1-Naphthaldehyde
H2O + E-Phenylitaconyl-CoA <-> (Hydroxymethylphenyl)succinyl-CoA
NAD+ + H2O + 2-Naphthaldehyde <-> NADH + H+ + 2-Naphthoic acid
O2 + 2-Oxoglutarate + 2,4-Dichlorophenoxyacetate <-> H2O + CO2 + Glyoxylate + Succinate + 2,4-Dichlorophenol
NAD+ + 2-Methylbenzyl alcohol <-> NADH + H+ + 2-Methylbenzaldehyde
NAD+ + Toluene-cis-dihydrodiol <-> NADH + H+ + 2,3-Dihydroxytoluene
Naphthyl-2-methyl-succinyl-CoA <-> 2 H+ + Naphthyl-2-methylene-succinyl-CoA
NADP+ + 3-Hydroxybenzyl alcohol <-> H+ + NADPH + 3-Hydroxybenzaldehyde
H+ + NADPH + O2 + o-Cresol <-> H2O + NADP+ + 2,3-Dihydroxytoluene
NAD+ + cis-1,2-Dihydronaphthalene-1,2-diol <-> NADH + H+ + Naphthalene-1,2-diol
Toluene <-> 4-Cresol
Succinyl-CoA + Benzylsuccinate <-> Succinate + Benzylsuccinyl-CoA
NAD+ + p-Cumic alcohol <-> NADH + H+ + p-Cumic aldehyde
H2O + Perillyl-CoA <-> 2-Hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA
Succinyl-CoA + Naphthyl-2-methyl-succinic acid <-> Succinate + Naphthyl-2-oxomethyl-succinyl-CoA
(1R,4R)-Dihydrocarvone <-> (4R,7R)-4-Isopropenyl-7-methyl-2-oxo-oxepanone
NAD+ + (3S,4R)-3,4-Dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate <-> NADH + H+ + CO2 + 3,4-Dihydroxybenzoate
O2 + Catechol <-> 2-Hydroxymuconate semialdehyde
H2O + 2-Hydroxyhexa-2,4-dienoate <-> 4-Hydroxy-2-oxohexanoate
O2 + 3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione <-> 3-Hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate
H2O + NADP+ + 3-Methylbenzaldehyde <-> H+ + NADPH + m-Methylbenzoate
Acetate + 2-Hydroxy-2,4-pentadienoate <-> H2O + 2-Hydroxy-6-keto-2,4-heptadienoate
O2 + Biphenyl-2,3-diol <-> 2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoate
NAD+ + 3,4,6-Trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene <-> NADH + H+ + 3,4,6-Trichlorocatechol
NAD+ + cis-1,2-Dihydrobenzene-1,2-diol <-> NADH + H+ + Catechol
NAD+ + (+)-cis-3,4-Dihydrophenanthrene-3,4-diol <-> NADH + H+ + Phenanthrene-3,4-diol
NAD+ + H2O + p-Cumic aldehyde <-> NADH + H+ + p-Cumate
2-Hydroxy-2H-benzo[h]chromene-2-carboxylate <-> cis-4-(1'-Hydroxynaphth-2'-yl)-2-oxobut-3-enoate
O2 + Catechol <-> cis,cis-Muconate
NAD+ + 3-Chloro-cis-1,2-dihydroxycyclohexa-3,5-diene <-> NADH + H+ + 3-Chlorocatechol
(S)-5-Oxo-2,5-dihydrofuran-2-acetate <-> 2-Oxo-2,3-dihydrofuran-5-acetate
ATP + Coenzyme A + (3R)-3-Isopropenyl-6-oxoheptanoate <-> ADP + Phosphate + H2O + (3R)-3-Isopropenyl-6-oxoheptanoyl-CoA
NAD+ + H2O + 2-Hydroxymuconate semialdehyde <-> NADH + H+ + 2-Hydroxymuconate
Acceptor + 2-Hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA <-> Reduced acceptor + 4-Isopropenyl-2-oxy-cyclohexanecarboxyl-CoA
NAD+ + Benzyl alcohol <-> NADH + H+ + Benzaldehyde
H2O + 2-Hydroxy-cis-hex-2,4-dienoate <-> 4-Hydroxy-2-oxohexanoate
O2 + 4-Methylcatechol <-> 3-Methyl-cis,cis-hexadienedioate
cis,cis-Muconate <-> (S)-5-Oxo-2,5-dihydrofuran-2-acetate
O2 + 2 4-Chlorophenoxyacetate <-> 2 Glyoxylate + 2 4-Chlorophenol
O2 + 3-Ethylcatechol <-> H+ + 2-Hydroxy-6-oxo-octa-2,4-dienoate
H+ + NADPH + O2 + 4-Chlorophenol <-> H2O + NADP+ + 4-Chlorocatechol
NAD+ + Coenzyme A + Propanal <-> NADH + H+ + Propanoyl-CoA
NAD+ + cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol <-> NADH + H+ + 3-(2,3-Dihydroxyphenyl)propanoate
Succinate + 2-Hydroxy-2,4-pentadienoate <-> H2O + 2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate
 Classification
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