Pathway Details

 Recommended name Chlorocyclohexane and chlorobenzene degradation
 Alternative names
 Reactions
2 Reduced glutathione + Tetrachlorohydroquinone <-> Oxidized glutathione + HCl + 2,3,6-Trichlorohydroquinone
NAD+ + 3,4,6-Trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene <-> NADH + H+ + 3,4,6-Trichlorocatechol
Pyruvate + Acetaldehyde <-> 4-Hydroxy-2-oxopentanoate
O2 + 4-Chlorocatechol <-> 3-Chloro-cis,cis-muconate
H+ + NADPH + O2 + Hydroquinone <-> H2O + NADP+ + Benzene-1,2,4-triol
3-Chloro-cis,cis-muconate <-> CO2 + HCl + Protoanemonin
O2 + 3,5-Dichlorocatechol <-> 2,4-Dichloro-cis,cis-muconate
Beta-1,2,3,4,5,6-hexachlorocyclohexane <-> 2 Cl- + Delta-3,4,5,6-tetrachlorocyclohexene
H2O + Protoanemonin <-> cis-Acetylacrylate
HCl + 1,2,4-Trichlorobenzene <-> 1,3,4,6-Tetrachloro-1,4-cyclohexadiene
NAD+ + 3-Oxoadipate <-> NADH + H+ + 2-Maleylacetate
H2O + 2,4,5-Trichloro-2,5-cyclohexadiene-1-ol <-> HCl + 2,5-Dichloro-2,5-cyclohexadiene-1,4-diol
5,6-Dichloro-1,3-cyclohexadiene <-> Cl- + Chlorobenzene
O2 + 3,6-Dichlorocatechol <-> 2,5-Dichloro-cis,cis-muconate
NADP+ + 3-Oxoadipate <-> H+ + NADPH + 2-Maleylacetate
2 NADH + H+ + O2 + 2,4,6-Trichlorophenol <-> Cl- + 2 NAD+ + OH- + 2,6-Dichlorohydroquinone
2-Chloro-3-oxoadipate <-> Succinate + Chloroacetic acid
NAD+ + 3,6-Dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene <-> NADH + H+ + 3,6-Dichlorocatechol
2 H+ + 2 NADPH + O2 + Pentachlorophenol <-> Cl- + H2O + 2 NADP+ + Tetrachlorohydroquinone
H2O + Chlorocyclohexane <-> Cl- + Cyclohexanol
O2 + 2 4-Chlorophenoxyacetate <-> 2 Glyoxylate + 2 4-Chlorophenol
Formate + 2-Hydroxy-2,4-pentadienoate <-> H2O + 2-Hydroxymuconate semialdehyde
H+ + 2,4-Dichlorophenoxyacetate + 2 e- <-> Cl- + 4-Chlorophenoxyacetate
O2 + 3-Chlorocatechol <-> 2-Chloro-cis,cis-muconate
H2O + 1-Chlorohexane <-> Cl- + 1-Hexanol
H2O + trans-4-Carboxymethylenebut-2-en-4-olide <-> 2-Maleylacetate
O2 + 2 2,4,5-Trichlorophenoxyacetic acid <-> 2 Glyoxylate + 2 2,4,5-Trichlorophenol
H+ + NADPH + O2 + Resorcinol <-> H2O + NADP+ + Benzene-1,2,4-triol
H2O + cis-4-Carboxymethylenebut-2-en-4-olide <-> 2-Maleylacetate
NADH + H+ + O2 + 1,4-Dichlorobenzene <-> NAD+ + 3,6-Dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene
gamma-Pentachlorocyclohexene <-> HCl + 1,3,4,6-Tetrachloro-1,4-cyclohexadiene
NAD+ + H2O + cis,trans-4-Hydroxymuconic semialdehyde <-> NADH + H+ + 2-Maleylacetate
O2 + Benzene-1,2,4-triol <-> 2-Maleylacetate
H2O + cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide <-> 2-Chloromaleylacetate
2,4,5-Trichloro-2,5-cyclohexadiene-1-ol <-> HCl + 2,5-Dichlorophenol
5-Chloro-1,2,4-trihydroxybenzene <-> HCl + 2-Hydroxy-1,4-benzoquinone
2-Chloro-cis,cis-muconate <-> HCl + trans-4-Carboxymethylenebut-2-en-4-olide
NAD+ + 2,5-Dichloro-2,5-cyclohexadiene-1,4-diol <-> NADH + H+ + 2,5-Dichlorohydroquinone
5,6-Dichloro-1,3-cyclohexadiene <-> 2 Cl- + Benzene
H2O + 2,5-Dichloro-carboxymethylenebut-2-en-4-olide <-> 2,5-Dichloro-4-oxohex-2-enedioate
H+ + 5-Chloro-2-hydroxymuconic semialdehyde <-> Cl- + 2-Hydroxymuconate semialdehyde
H2O + 1,3,4,6-Tetrachloro-1,4-cyclohexadiene <-> HCl + 2,4,5-Trichloro-2,5-cyclohexadiene-1-ol
2-Chloro-2,5-dihydro-5-oxofuran-2-acetate <-> Cl- + cis-4-Carboxymethylenebut-2-en-4-olide
2 Reduced glutathione + 2,5-Dichlorohydroquinone <-> Oxidized glutathione + HCl + Chlorohydroquinone
gamma-Hexachlorocyclohexane <-> HCl + gamma-Pentachlorocyclohexene
cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide <-> trans-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide
H+ + NADPH + O2 + 4-Chlorophenol <-> H2O + NADP+ + 4-Chlorocatechol
O2 + 4-Chlorocatechol <-> 5-Chloro-2-hydroxymuconic semialdehyde
H2O + 2,6-Dichlorohydroquinone <-> HCl + 6-Chlorobenzene-1,2,4-triol
HCl + trans-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide <-> 2,5-Dichloro-cis,cis-muconate
O2 + Hydroquinone <-> cis,trans-4-Hydroxymuconic semialdehyde
NADH + H+ + 2-Hydroxy-1,4-benzoquinone <-> NAD+ + Benzene-1,2,4-triol
2 NADH + H+ + O2 + 2,5-Dichlorohydroquinone <-> Cl- + 2 NAD+ + OH- + 5-Chloro-1,2,4-trihydroxybenzene
2,3,5-Trichloro-cis,cis-muconate <-> HCl + 2,5-Dichloro-carboxymethylenebut-2-en-4-olide
2 Reduced glutathione + 2,3,6-Trichlorohydroquinone <-> Oxidized glutathione + HCl + 2,6-Dichlorohydroquinone
NAD+ + cis-1,2-Dihydrobenzene-1,2-diol <-> NADH + H+ + Catechol
O2 + 2-Oxoglutarate + 2,4-Dichlorophenoxyacetate <-> H2O + CO2 + Glyoxylate + Succinate + 2,4-Dichlorophenol
O2 + 3,4,6-Trichlorocatechol <-> 2,3,5-Trichloro-cis,cis-muconate
2 NADH + H+ + O2 + 2,4,5-Trichlorophenol <-> Cl- + 2 NAD+ + OH- + 2,5-Dichlorohydroquinone
1,4-Dichlorobenzene <-> Chlorobenzene
O2 + 4-Chlorocatechol <-> H2O + 3-Chloro-cis,cis-muconate
1,2,4-Trichlorobenzene <-> 1,4-Dichlorobenzene
H2O + O2 + 2,6-Dichlorohydroquinone <-> HCl + 2-Chloromaleylacetate
Delta-3,4,5,6-tetrachlorocyclohexene <-> 2 Cl- + 5,6-Dichloro-1,3-cyclohexadiene
Oxidized glutathione + Hydroquinone + HCl <-> 2 Reduced glutathione + Chlorohydroquinone
2-Chloro-2,5-dihydro-5-oxofuran-2-acetate <-> 3-Chloro-cis,cis-muconate
2,4-Dichloro-cis,cis-muconate <-> HCl + trans-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide
H+ + NADPH + O2 + 2,4-Dichlorophenol <-> H2O + NADP+ + 3,5-Dichlorocatechol
NAD+ + 3-Chloro-cis-1,2-dihydroxycyclohexa-3,5-diene <-> NADH + H+ + 3-Chlorocatechol
H2O + Bromocyclohexane <-> Br- + Cyclohexanol
NADH + H+ + O2 + 2,6-Dichlorophenol <-> NAD+ + H2O + 2,6-Dichlorohydroquinone
H2O + Chloroacetic acid <-> Glycolate + HCl
 Classification
Xenobiotics Biodegradation and Metabolism
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