Pathway Details

 Recommended name Steroid biosynthesis
 Alternative names
 Reactions
NAD+ + Cholesterol <-> NADH + H+ + Cholesta-5,7-dien-3beta-ol
NADP+ + Cholesterol <-> H+ + NADPH + Cholesta-5,7-dien-3beta-ol
NADP+ + Cholesterol <-> H+ + NADPH + Desmosterol
Acyl-CoA + Cholesterol <-> Coenzyme A + Cholesterol ester
Sterol <-> (S)-2,3-Epoxysqualene
Cholesterol + 1,2-Diacyl-sn-glycerol <-> Cholesterol ester + Acylglycerol
H+ + NADPH + O2 + Squalene <-> H2O + NADP+ + (S)-2,3-Epoxysqualene
(S)-2,3-Epoxysqualene <-> Lanosterol
(S)-2,3-Epoxysqualene <-> Cycloartenol
5alpha-Cholest-7-en-3beta-ol <-> 5alpha-Cholest-8-en-3beta-ol
H+ + NADPH + O2 + Calcidiol <-> H2O + NADP+ + Calcitriol
Acceptor + Desmosterol <-> Reduced acceptor + 7-Dehydrodesmosterol
Cycloeucalenol <-> Obtusifoliol
S-Adenosyl-L-methionine + Zymosterol <-> S-Adenosyl-L-homocysteine + 24-Methylene-5alpha-cholest-8-en-3beta-ol
Zymosterol <-> 5alpha-Cholesta-7,24-dien-3beta-ol
NADP+ + 14-Demethyllanosterol <-> H+ + NADPH + 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
3 H+ + 3 NADPH + 3 O2 + Lanosterol <-> 4 H2O + 3 NADP+ + Formate + 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
NADP+ + Ergosterol <-> H+ + NADPH + Ergosta-5,7,22,24(28)-tetraen-3beta-ol
NADP+ + 5alpha-Cholest-7-en-3beta-ol <-> H+ + NADPH + 5alpha-Cholesta-7,24-dien-3beta-ol
3 H+ + 3 NADPH + 3 O2 + Obtusifoliol <-> 4 H2O + 3 NADP+ + Formate + 4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol
S-Adenosyl-L-methionine + 24-Methylene lophenol <-> S-Adenosyl-L-homocysteine + 24-Ethylidene lophenol
H2O + Cholesterol ester <-> Cholesterol + Fatty acid
H+ + NADPH + O2 + 5alpha-Cholest-7-en-3beta-ol <-> 2 H2O + NADP+ + Cholesta-5,7-dien-3beta-ol
S-Adenosyl-L-methionine + Cycloartenol <-> S-Adenosyl-L-homocysteine + 24-Methylenecycloartanol
 Classification
Lipid Metabolism
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