Pathway Details

 Recommended name Toluene degradation
 Alternative names
 Reactions
Succinate + Acceptor <-> Fumarate + Reduced acceptor
Pyruvate + Acetaldehyde <-> 4-Hydroxy-2-oxopentanoate
NAD+ + H2O + 4-Hydroxybenzaldehyde <-> NADH + H+ + 4-Hydroxybenzoate
H2O + NADP+ + 4-Hydroxybenzaldehyde <-> H+ + NADPH + 4-Hydroxybenzoate
NAD+ + H2O + Benzaldehyde <-> NADH + H+ + Benzoate
H2O + NADP+ + Benzaldehyde <-> H+ + NADPH + Benzoate
NAD+ + Benzyl alcohol <-> NADH + H+ + Benzaldehyde
NAD+ + H2O + Benzyl alcohol <-> NADH + H+ + O2 + Toluene
H2O + 2-Hydroxy-2,4-pentadienoate <-> 4-Hydroxy-2-oxopentanoate
O2 + Ferredoxin + 4-Cresol <-> H2O + Oxidized ferredoxin + 4-Hydroxybenzaldehyde
NADH + H+ + O2 + Toluene <-> NAD+ + Toluene-cis-dihydrodiol
H+ + NADPH + O2 + Toluene <-> H2O + NADP+ + o-Cresol
H+ + NADPH + O2 + Toluene <-> H2O + NADP+ + 3-Cresol
H+ + NADPH + O2 + 3-Cresol <-> H2O + NADP+ + 2,3-Dihydroxytoluene
H2O + Oxidized ferredoxin + 4-Cresol <-> O2 + Ferredoxin + Toluene
H+ + NADPH + O2 + o-Cresol <-> H2O + NADP+ + 2,3-Dihydroxytoluene
NAD+ + Toluene-cis-dihydrodiol <-> NADH + H+ + 2,3-Dihydroxytoluene
O2 + 2,3-Dihydroxytoluene <-> 2-Hydroxy-6-keto-2,4-heptadienoate
NADP+ + 3-Hydroxybenzyl alcohol <-> H+ + NADPH + 3-Hydroxybenzaldehyde
4-Carboxymethyl-4-methylbut-2-en-1,4-olide <-> 4-Carboxymethyl-3-methylbut-2-en-1,4-olide
Acetate + 2-Hydroxy-2,4-pentadienoate <-> H2O + 2-Hydroxy-6-keto-2,4-heptadienoate
NAD+ + 4-Sulfobenzyl alcohol <-> NADH + H+ + 4-Sulfobenzaldehyde
NAD+ + H2O + 4-Sulfobenzaldehyde <-> NADH + H+ + 4-Sulfobenzoate
NAD+ + alpha-Hydroxy-p-xylene <-> NADH + H+ + p-Tolualdehyde
NADH + H+ + O2 + p-Xylene <-> NAD+ + H2O + alpha-Hydroxy-p-xylene
H2O + NADP+ + p-Tolualdehyde <-> H+ + NADPH + Toluate
NADH + H+ + O2 + Toluate <-> NAD+ + cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate
H+ + NADPH + O2 + Toluate <-> NADP+ + cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate
NAD+ + cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate <-> NADH + H+ + CO2 + 4-Methylcatechol
NADP+ + cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate <-> H+ + NADPH + CO2 + 4-Methylcatechol
NADH + H+ + O2 + Toluene-4-sulfonate <-> NAD+ + 4-Methylcatechol + HSO3-
O2 + 4-Methylcatechol <-> 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde
Pyruvate + Propanal <-> 4-Hydroxy-2-oxohexanoate
O2 + 4-Methylcatechol <-> 3-Methyl-cis,cis-hexadienedioate
4-Carboxymethyl-4-methylbut-2-en-1,4-olide <-> 3-Methyl-cis,cis-hexadienedioate
NAD+ + 1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate <-> NADH + H+ + CO2 + 2,3-Dihydroxytoluene
NAD+ + 1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate <-> NADH + H+ + CO2 + 2,3-Dihydroxytoluene
NAD+ + 3-Methylbenzyl alcohol <-> NADH + H+ + 3-Methylbenzaldehyde
NAD+ + 2-Methylbenzyl alcohol <-> NADH + H+ + 2-Methylbenzaldehyde
NAD+ + H2O + 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde <-> NADH + H+ + 2-Hydroxy-5-methyl-cis,cis-muconate
2-Oxo-5-methyl-cis-muconate <-> CO2 + 2-Hydroxy-cis-hex-2,4-dienoate
2-Hydroxy-5-methyl-cis,cis-muconate <-> 2-Oxo-5-methyl-cis-muconate
NADH + H+ + O2 + o-Toluate <-> NAD+ + 1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate
NADH + H+ + O2 + o-Xylene <-> NAD+ + H2O + 2-Methylbenzyl alcohol
NADH + H+ + O2 + m-Xylene <-> NAD+ + H2O + 3-Methylbenzyl alcohol
O2 + Reduced rubredoxin + o-Xylene <-> H2O + Oxidized rubredoxin + 2-Methylbenzyl alcohol
O2 + Reduced rubredoxin + p-Xylene <-> H2O + Oxidized rubredoxin + alpha-Hydroxy-p-xylene
O2 + Reduced rubredoxin + m-Xylene <-> H2O + Oxidized rubredoxin + 3-Methylbenzyl alcohol
NAD+ + (Hydroxymethylphenyl)succinyl-CoA <-> NADH + H+ + Benzoylsuccinyl-CoA
Coenzyme A + Benzoylsuccinyl-CoA <-> Succinyl-CoA + Benzoyl-CoA
Succinyl-CoA + Benzylsuccinate <-> Succinate + Benzylsuccinyl-CoA
Fumarate + Toluene <-> Benzylsuccinate
H2O + E-Phenylitaconyl-CoA <-> (Hydroxymethylphenyl)succinyl-CoA
H2O + NADP+ + 2-Methylbenzaldehyde <-> H+ + NADPH + o-Toluate
H2O + NADP+ + 3-Methylbenzaldehyde <-> H+ + NADPH + m-Methylbenzoate
NADH + H+ + O2 + m-Methylbenzoate <-> NAD+ + 1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate
Toluene <-> 4-Cresol
H2O + 2-Hydroxy-cis-hex-2,4-dienoate <-> 4-Hydroxy-2-oxohexanoate
H2O + 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde <-> Formate + 2-Hydroxy-cis-hex-2,4-dienoate
NAD+ + H+ + 2 Reduced ferredoxin <-> NADH + 2 Oxidized ferredoxin
Pyruvate + Benzaldehyde <-> CO2 + R-Phenylacetylcarbinol
H2O + Acceptor + Benzylamine <-> NH3 + Benzaldehyde + Reduced acceptor
NAD+ + H2O + 3-Hydroxybenzaldehyde <-> NADH + H+ + 3-Hydroxybenzoate
2 Electron-transferring flavoprotein + Benzylsuccinyl-CoA <-> 2 Reduced electron-transferring flavoprotein + E-Phenylitaconyl-CoA
Succinyl-CoA + (R)-2-Benzylsuccinate <-> Succinate + (R)-2-Benzylsuccinyl-CoA
 Classification
Xenobiotics Biodegradation and Metabolism
© HITS gGmbH