Pathway Details

 Recommended name Toluene degradation
 Alternative names
 Reactions
H+ + NADPH + O2 + Toluate <-> NADP+ + cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate
Acetate + 2-Hydroxy-2,4-pentadienoate <-> H2O + 2-Hydroxy-6-keto-2,4-heptadienoate
Succinyl-CoA + Benzylsuccinate <-> Succinate + Benzylsuccinyl-CoA
Pyruvate + Acetaldehyde <-> 4-Hydroxy-2-oxopentanoate
H2O + 2-Hydroxy-2,4-pentadienoate <-> 4-Hydroxy-2-oxopentanoate
Toluene <-> 4-Cresol
NAD+ + H2O + Benzyl alcohol <-> NADH + H+ + O2 + Toluene
H2O + NADP+ + Benzaldehyde <-> H+ + NADPH + Benzoate
H2O + NADP+ + 4-Hydroxybenzaldehyde <-> H+ + NADPH + 4-Hydroxybenzoate
Pyruvate + Propanal <-> 4-Hydroxy-2-oxohexanoate
NADH + H+ + O2 + p-Xylene <-> NAD+ + H2O + alpha-Hydroxy-p-xylene
NAD+ + cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate <-> NADH + H+ + CO2 + 4-Methylcatechol
H2O + NADP+ + p-Tolualdehyde <-> H+ + NADPH + Toluate
NAD+ + H2O + 4-Hydroxybenzaldehyde <-> NADH + H+ + 4-Hydroxybenzoate
H2O + NADP+ + 3-Methylbenzaldehyde <-> H+ + NADPH + m-Methylbenzoate
Succinate + Acceptor <-> Fumarate + Reduced acceptor
O2 + 2,3-Dihydroxytoluene <-> 2-Hydroxy-6-keto-2,4-heptadienoate
NAD+ + Toluene-cis-dihydrodiol <-> NADH + H+ + 2,3-Dihydroxytoluene
NADH + H+ + O2 + o-Toluate <-> NAD+ + 1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate
NAD+ + 1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate <-> NADH + H+ + CO2 + 2,3-Dihydroxytoluene
NADP+ + cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate <-> H+ + NADPH + CO2 + 4-Methylcatechol
O2 + Reduced rubredoxin + o-Xylene <-> H2O + Oxidized rubredoxin + 2-Methylbenzyl alcohol
H2O + 2-Hydroxy-cis-hex-2,4-dienoate <-> 4-Hydroxy-2-oxohexanoate
O2 + 4-Methylcatechol <-> 3-Methyl-cis,cis-hexadienedioate
H+ + NADPH + O2 + Toluene <-> H2O + NADP+ + 3-Cresol
NADP+ + 3-Hydroxybenzyl alcohol <-> H+ + NADPH + 3-Hydroxybenzaldehyde
NAD+ + H2O + 4-Sulfobenzaldehyde <-> NADH + H+ + 4-Sulfobenzoate
NAD+ + (Hydroxymethylphenyl)succinyl-CoA <-> NADH + H+ + Benzoylsuccinyl-CoA
NADH + H+ + O2 + m-Methylbenzoate <-> NAD+ + 1,6-Dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate
NAD+ + H2O + Benzaldehyde <-> NADH + H+ + Benzoate
NADH + H+ + O2 + m-Xylene <-> NAD+ + H2O + 3-Methylbenzyl alcohol
O2 + 4-Methylcatechol <-> 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde
NAD+ + H2O + 3-Hydroxybenzaldehyde <-> NADH + H+ + 3-Hydroxybenzoate
NADH + H+ + O2 + Toluate <-> NAD+ + cis-1,2-Dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate
H2O + Oxidized ferredoxin + 4-Cresol <-> O2 + Ferredoxin + Toluene
NAD+ + 3-Methylbenzyl alcohol <-> NADH + H+ + 3-Methylbenzaldehyde
NAD+ + 4-Sulfobenzyl alcohol <-> NADH + H+ + 4-Sulfobenzaldehyde
O2 + Ferredoxin + 4-Cresol <-> H2O + Oxidized ferredoxin + 4-Hydroxybenzaldehyde
H2O + Acceptor + Benzylamine <-> NH3 + Benzaldehyde + Reduced acceptor
H+ + NADPH + O2 + Toluene <-> H2O + NADP+ + o-Cresol
Succinyl-CoA + (R)-2-Benzylsuccinate <-> Succinate + (R)-2-Benzylsuccinyl-CoA
H2O + NADP+ + 2-Methylbenzaldehyde <-> H+ + NADPH + o-Toluate
H+ + NADPH + O2 + o-Cresol <-> H2O + NADP+ + 2,3-Dihydroxytoluene
Coenzyme A + Benzoylsuccinyl-CoA <-> Succinyl-CoA + Benzoyl-CoA
NAD+ + Benzyl alcohol <-> NADH + H+ + Benzaldehyde
NADH + H+ + O2 + Toluene <-> NAD+ + Toluene-cis-dihydrodiol
NAD+ + alpha-Hydroxy-p-xylene <-> NADH + H+ + p-Tolualdehyde
4-Carboxymethyl-4-methylbut-2-en-1,4-olide <-> 4-Carboxymethyl-3-methylbut-2-en-1,4-olide
Pyruvate + Benzaldehyde <-> CO2 + R-Phenylacetylcarbinol
O2 + Reduced rubredoxin + p-Xylene <-> H2O + Oxidized rubredoxin + alpha-Hydroxy-p-xylene
NADH + H+ + O2 + o-Xylene <-> NAD+ + H2O + 2-Methylbenzyl alcohol
O2 + Reduced rubredoxin + m-Xylene <-> H2O + Oxidized rubredoxin + 3-Methylbenzyl alcohol
2-Oxo-5-methyl-cis-muconate <-> CO2 + 2-Hydroxy-cis-hex-2,4-dienoate
Fumarate + Toluene <-> Benzylsuccinate
NADH + H+ + O2 + Toluene-4-sulfonate <-> NAD+ + 4-Methylcatechol + HSO3-
4-Carboxymethyl-4-methylbut-2-en-1,4-olide <-> 3-Methyl-cis,cis-hexadienedioate
H2O + 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde <-> Formate + 2-Hydroxy-cis-hex-2,4-dienoate
H2O + E-Phenylitaconyl-CoA <-> (Hydroxymethylphenyl)succinyl-CoA
NAD+ + H+ + 2 Reduced ferredoxin <-> NADH + 2 Oxidized ferredoxin
H+ + NADPH + O2 + 3-Cresol <-> H2O + NADP+ + 2,3-Dihydroxytoluene
2-Hydroxy-5-methyl-cis,cis-muconate <-> 2-Oxo-5-methyl-cis-muconate
NAD+ + H2O + 2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde <-> NADH + H+ + 2-Hydroxy-5-methyl-cis,cis-muconate
NAD+ + 1,2-Dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate <-> NADH + H+ + CO2 + 2,3-Dihydroxytoluene
2 Electron-transferring flavoprotein + Benzylsuccinyl-CoA <-> 2 Reduced electron-transferring flavoprotein + E-Phenylitaconyl-CoA
NAD+ + 2-Methylbenzyl alcohol <-> NADH + H+ + 2-Methylbenzaldehyde
 Classification
Xenobiotics Biodegradation and Metabolism
© HITS gGmbH