Pathway Details

Recommended name

Naphthalene degradation

Alternative names

Reactions

NAD+ + cis-1,2-Dihydronaphthalene-1,2-diol <-> NADH + H+ + Naphthalene-1,2-diol

O2 + Naphthalene-1,2-diol <-> 2-Hydroxychromene-2-carboxylate

trans-O-Hydroxybenzylidenepyruvate <-> 2-Hydroxychromene-2-carboxylate

NAD+ + H2O + 2-Naphthaldehyde <-> NADH + H+ + 2-Naphthoic acid

NAD+ + H2O + Salicylaldehyde <-> NADH + H+ + Salicylate

2-Naphthoic acid <-> 5,6,7,8-Tetrahydro-2-naphthoic acid

5,6,7,8-Tetrahydro-2-naphthoic acid <-> Decahydro-2-naphthoic acid

5,6,7,8-Tetrahydro-2-naphthoic acid <-> cis-2-Carboxycyclohexyl-acetic acid

Tetralin <-> 5,6,7,8-Tetrahydro-2-naphthoic acid

2-Naphthoic acid <-> 1-Hydroxy-2-naphthoate

Fumarate + 2-Methylnaphthalene <-> Naphthyl-2-methyl-succinic acid

Succinyl-CoA + Naphthyl-2-methyl-succinic acid <-> Succinate + Naphthyl-2-oxomethyl-succinyl-CoA

H2O + Naphthyl-2-methylene-succinyl-CoA <-> Naphthyl-2-hydroxymethyl-succinyl CoA

Coenzyme A + Naphthyl-2-methyl-succinyl-CoA <-> Succinyl-CoA + 2-Naphthoyl-CoA

NAD+ + cis-1,2-Dihydroxy-1,2-dihydro-8-methylnaphthalene <-> NADH + H+ + 1,2-Dihydroxy-8-methylnaphthalene

O2 + 1,2-Dihydroxy-8-methylnaphthalene <-> 2-Hydroxy-8-methylchromene-2-carboxylate

2-Hydroxy-8-methylchromene-2-carboxylate <-> 2-Hydroxy-3-methylbenzalpyruvate

H2O + 2-Hydroxy-3-methylbenzalpyruvate <-> Pyruvate + 3-Methylsalicylaldehyde

NAD+ + H2O + 3-Methylsalicylaldehyde <-> NADH + H+ + 3-Methylsalicylate

NAD+ + 1-Hydroxymethylnaphthalene <-> NADH + H+ + 1-Naphthaldehyde

NAD+ + H2O + 1-Naphthaldehyde <-> NADH + H+ + 1-Naphthoic acid

cis-1,2-Dihydroxy-1,2-dihydro-8-carboxynaphthalene <-> 1,2-Dihydroxy-8-carboxynaphthalene

O2 + 1,2-Dihydroxy-8-carboxynaphthalene <-> 2-Carboxy-2-hydroxy-8-carboxychromene

2-Carboxy-2-hydroxy-8-carboxychromene <-> 2-Hydroxy-3-carboxybenzalpyruvate

H2O + 2-Hydroxy-3-carboxybenzalpyruvate <-> Pyruvate + 3-Formylsalicylic acid

H2O + O2 + 3-Formylsalicylic acid <-> H2O2 + 2-Hydroxyisophthalic acid

2-Hydroxyisophthalic acid <-> CO2 + Salicylate

NAD+ + (2-Naphthyl)methanol <-> NADH + H+ + 2-Naphthaldehyde

2-Naphthaldehyde <-> 4-Formylsalicylic acid

NAD+ + cis-1,2-Dihydroxy-1,2-dihydro-7-hydroxymethylnaphthalene <-> NADH + H+ + 1,2-Dihydroxy-7-hydroxymethylnaphthalene

O2 + 1,2-Dihydroxy-7-hydroxymethylnaphthalene <-> 2-Hydroxy-7-hydroxymethylchromene-2-carboxylate

2-Hydroxy-7-hydroxymethylchromene-2-carboxylate <-> 2-Hydroxy-4-hydroxymethylbenzalpyruvate

H2O + 2-Hydroxy-4-hydroxymethylbenzalpyruvate <-> Pyruvate + 4-Hydroxymethylsalicylaldehyde

NAD+ + H2O + 4-Hydroxymethylsalicylaldehyde <-> NADH + H+ + 4-Hydroxymethylsalicylate

cis-1,2-Dihydroxy-1,2-dihydro-7-methylnaphthalene <-> 4-Methylsalicylate

Naphthyl-2-methyl-succinyl-CoA <-> 2 H+ + Naphthyl-2-methylene-succinyl-CoA

Naphthyl-2-hydroxymethyl-succinyl CoA <-> 2 H+ + Naphthyl-2-oxomethyl-succinyl-CoA

Classification

Xenobiotics Biodegradation and Metabolism

© HITS gGmbH