Pathway Details

 Recommended name Arachidonic acid metabolism
 Alternative names
 Reactions
NADH + H+ + O2 + Leukotriene B4 <-> NAD+ + H2O + 19-OH-Leukotriene B4
11-epi-Prostaglandin F2alpha <-> 2 H+ + Prostaglandin D2
2 Reduced glutathione + 5-Hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoate <-> H2O + Oxidized glutathione + 5-Hydroxyeicosatetraenoate
H2O + Prostaglandin I2 <-> 6-Keto-prostaglandin F1alpha
Lipoxin <-> 15-HPETE
Prostaglandin A2 <-> Prostaglandin C2
2 O2 + Arachidonate <-> Prostaglandin G2
NADP+ + Prostaglandin F2alpha <-> H+ + NADPH + Prostaglandin E2
NADP+ + Leukotriene B4 <-> H+ + NADPH + 12-Keto-leukotriene B4
Prostaglandin H2 <-> Prostaglandin I2
H2O + 8,9-EET <-> 8,9-DHET
Prostaglandin H2 <-> Prostaglandin E2
H2O + Leukotriene A4 <-> Leukotriene B4
L-Glutamate + Leukotriene E4 <-> H2O + Leukotriene F4
H2O + 11,12-EET <-> 11,12-DHET
H2O + Leukotriene C4 <-> Glutamate + Leukotriene D4
H+ + NADPH + O2 + Arachidonate <-> H2O + NADP+ + 19(S)-HETE
H2O + Hepoxilin B3 <-> Trioxilin B3
15-HPETE <-> 15H-11,12-EETA
H+ + NADPH + Prostaglandin D2 <-> NADP+ + 9alpha,11beta-Prostaglandin F2
H2O + Leukotriene D4 <-> Glycine + Leukotriene E4
NADH + H+ + Prostaglandin D2 <-> NAD+ + 9alpha,11beta-Prostaglandin F2
H+ + NADPH + O2 + Leukotriene B4 <-> H2O + NADP+ + 19-OH-Leukotriene B4
H+ + NADPH + O2 + Arachidonate <-> H2O + NADP+ + 16(R)-HETE
H+ + NADPH + O2 + Leukotriene B4 <-> H2O + NADP+ + 20-OH-Leukotriene B4
O2 + Arachidonate <-> 12(R)-HPETE
Prostaglandin D2 <-> H2O + Prostaglandin J2
H2O + 15H-11,12-EETA <-> 11,12,15-THETA
delta-12-13,14-Dihydro-prostaglandin J2 <-> H2O + 15-Deoxy-delta-12,14-PGJ2
H+ + NADPH + O2 + Arachidonate <-> H2O + NADP+ + 20-HETE
Acceptor + 6-Keto-prostaglandin F1alpha <-> Reduced acceptor + 6-Keto-prostaglandin E1
H2O + 5,6-EET <-> 5,6-DHET
H2O + 5,6-Epoxytetraene <-> Lipoxin B4
H+ + NADPH + O2 + Arachidonate <-> H2O + NADP+ + 11,12-EET
Acceptor + Thromboxane B2 <-> Reduced acceptor + 11-Dehydro-thromboxane B2
NAD+ + (15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate <-> NADH + H+ + 15-Oxo-5,8,11-cis-13-trans-eicosatetraenoate
15-HPETE <-> 11H-14,15-EETA
H+ + NADPH + O2 + Leukotriene E4 <-> H2O + NADP+ + 20-Hydroxy-leukotriene E4
12-HPETE <-> Hepoxilin B3
H+ + NADPH + Prostaglandin J2 <-> Unknown + NADP+
H2O + 14,15-EET <-> 14,15-DHET
O2 + Arachidonate <-> 8(S)-HPETE
H2O + 5,6-Epoxytetraene <-> Lipoxin A4
H+ + NADPH + O2 + Arachidonate <-> H2O + NADP+ + 8,9-EET
Prostaglandin B2 <-> Prostaglandin C2
O2 + Arachidonate <-> 5-Hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoate
2 Reduced glutathione + 15-HPETE <-> H2O + Oxidized glutathione + (15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate
H2O + 11H-14,15-EETA <-> 11,14,15-THETA
2 H+ + Acceptor + Prostaglandin H2 <-> Reduced acceptor + Prostaglandin F2alpha
H+ + NADPH + O2 + Arachidonate <-> H2O + NADP+ + 5,6-EET
NADP+ + (15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate <-> H+ + NADPH + 15-Oxo-5,8,11-cis-13-trans-eicosatetraenoate
Prostaglandin J2 <-> delta-12-13,14-Dihydro-prostaglandin J2
O2 + Arachidonate <-> 15-HPETE
Reduced glutathione + Leukotriene A4 <-> Leukotriene C4
NAD+ + Prostaglandin F2alpha <-> NADH + H+ + 15-Keto-prostaglandin F2alpha
Prostaglandin H2 <-> Prostaglandin D2
NAD+ + Leukotriene B4 <-> NADH + H+ + 12-Keto-leukotriene B4
O2 + 2 Prostaglandin H2 <-> 2 Prostaglandin G2
Prostaglandin H2 <-> Thromboxane A2
Reduced acceptor + 5-Hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoate <-> H2O + Acceptor + 5-Hydroxyeicosatetraenoate
O2 + Arachidonate <-> 11(R)-HPETE
H2O + Phosphatidylcholine <-> Arachidonate + Lysophospholipid
5-Hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoate <-> H2O + Leukotriene A4
H+ + NADPH + Prostaglandin D1 <-> NADP+ + Prostaglandin F1alpha
NADH + H+ + O2 + Leukotriene B4 <-> NAD+ + H2O + 20-OH-Leukotriene B4
H+ + NADPH + Prostaglandin D3 <-> NADP+ + Prostaglandin F3alpha
O2 + Arachidonate <-> 12-HPETE
H+ + NADPH + O2 + Arachidonate <-> H2O + NADP+ + 14,15-EET
H2O + Thromboxane A2 <-> Thromboxane B2
O2 + Arachidonate <-> 9(S)-HPETE
Prostaglandin E2 <-> H2O + Prostaglandin A2
 Classification
Lipid Metabolism
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