Pathway Details

 Recommended name Clavulanic acid biosynthesis
 Alternative names
 Reactions
H2O + Guanidinoproclavaminic acid <-> Urea + Proclavaminic acid
Pyruvate + Arginine <-> L-N2-(2-Carboxyethyl)arginine
O2 + 2-Oxoglutarate + Deoxyguanidinoproclavaminic acid <-> H2O + CO2 + Succinate + Guanidinoproclavaminic acid
ATP + L-N2-(2-Carboxyethyl)arginine <-> Diphosphate + AMP + Deoxyguanidinoproclavaminic acid
O2 + 2-Oxoglutarate + Proclavaminic acid <-> 2 H2O + CO2 + Succinate + Dihydroclavaminic acid
O2 + 2-Oxoglutarate + Dihydroclavaminic acid <-> 2 H2O + CO2 + Succinate + Clavaminic acid
Clavaminic acid <-> Clavulanate-9-aldehyde
Clavulanate-9-aldehyde <-> Clavulanic acid
O2 + 2-Oxoglutarate + Deoxyguanidinoproclavaminic acid <-> CO2 + Succinate + Guanidinoproclavaminic acid
D-Glyceraldehyde 3-phosphate + L-Arginine <-> Phosphate + L-N2-(2-Carboxyethyl)arginine
 Classification
Biosynthesis of Other Secondary Metabolites
© HITS gGmbH