Enzyme Details

EC Classification

6.3.4.2

Enzyme name
(recommended)

CTP synthase

Alternative names

UTP:ammonia ligase (ADP-forming)
UTP---ammonia ligase
cytidine triphosphate synthetase
uridine triphosphate aminase
cytidine 5'-triphosphate synthetase

Classification

Ligases

Forming carbon-nitrogen bonds

Other carbon--nitrogen ligases

Catalyses reactions

ATP + NH3 + UTP <-> ADP + Phosphate + CTP

ATP + H2O + L-Glutamine + UTP <-> ADP + Phosphate + L-Glutamate + CTP

H2O + L-Glutamine <-> L-Glutamate + NH3

H2O + L-gamma-Glutamyl hydrazide <-> L-Glutamate + Hydrazine

H2O + L-gamma-Glutamyl hydroxamate <-> L-Glutamate + Hydroxylamine

ATP + UTP + Hydrazine <-> ADP + Phosphate + N4-Amino-CTP

ATP + UTP + Hydroxylamine <-> ADP + Phosphate + N4-Hydroxyl-CTP

ATP + H2O + UTP + L-gamma-Glutamyl hydrazide <-> ADP + Phosphate + L-Glutamate + N4-Amino-CTP

ATP + H2O + UTP + L-gamma-Glutamyl hydroxamate <-> ADP + Phosphate + L-Glutamate + N4-Hydroxyl-CTP

ATP + H2O + L-Glutamine + dUTP <-> ADP + Phosphate + L-Glutamate + dCTP

H2O + L-Glutamine + UTP + Adenosine 5-O-(3-thiotriphosphate) <-> ADP + L-Glutamate + CTP + Thiophosphate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 6.3.4.2