Enzyme Details

EC Classification

6.3.2.7

Enzyme name
(recommended)

UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---L-lysine ligase

Alternative names

UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine gamma-ligase (ADP-forming)
MurE synthetase
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine synthetase
uridine diphospho-N-acetylmuramoylalanyl-D-glutamyllysine synthetase
UPD-MurNAc-L-Ala-D-Glu:L-Lys ligase

Classification

Ligases

Forming carbon-nitrogen bonds

Acid--amino-acid ligases (peptide synthases)

Catalyses reactions

ATP + L-Lysine + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate <-> ADP + Phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine

ATP + L-Lysine + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate <-> ADP + Phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 6.3.2.7