Enzyme Details

 EC Classification 6.3.2.12
 Enzyme name
(recommended)
dihydrofolate synthase
 Alternative names 7,8-dihydropteroate:L-glutamate ligase (ADP-forming)
dihydrofolate synthetase
7,8-dihydrofolate synthetase
H2-folate synthetase
7,8-dihydropteroate:L-glutamate ligase (ADP)
dihydrofolate synthetase-folylpolyglutamate synthetase
folylpoly-(gamma-glutamate) synthetase-dihydrofolate synthase
FHFS
FHFS/FPGS
dihydropteroate:L-glutamate ligase (ADP-forming)
DHFS
 Classification
Ligases
Forming carbon-nitrogen bonds
Acid--amino-acid ligases (peptide synthases)
 Catalyses reactions
ATP + L-Glutamate + 10-Formyltetrahydrofolate <-> ADP + Phosphate + 10-Formyltetrahydrofolyl L-glutamate
ATP + L-Glutamate + Dihydropteroate <-> ADP + Phosphate + Dihydrofolate
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 6.3.2.12



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