Enzyme Details

EC Classification

6.2.1.4

Enzyme name
(recommended)

succinate---CoA ligase (GDP-forming)

Alternative names

succinate:CoA ligase (GDP-forming)
succinyl-CoA synthetase (GDP-forming)
succinyl coenzyme A synthetase (guanosine diphosphate-forming)
succinate thiokinase
succinic thiokinase
succinyl coenzyme A synthetase
succinate-phosphorylating enzyme
P-enzyme
SCS
G-STK
succinyl coenzyme A synthetase (GDP-forming)
succinyl CoA synthetase
succinyl coenzyme A synthetase

Classification

Ligases

Forming carbon-sulfur bonds

Acid--thiol ligases

Catalyses reactions

Coenzyme A + GTP + Succinate <-> Phosphate + GDP + Succinyl-CoA

Coenzyme A + ITP + Succinate <-> Phosphate + IDP + Succinyl-CoA

Coenzyme A + GTP + Itaconate <-> Phosphate + GDP + Itaconyl-CoA

Coenzyme A + ITP + Itaconate <-> Phosphate + IDP + Itaconyl-CoA

Phosphate + Succinyl-CoA + 8-Azaguanosine-5'-diphosphate <-> Coenzyme A + Succinate + 8-Azaguanosine-5'-triphosphate

H2O + Succinyl-CoA <-> Coenzyme A + Succinate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 6.2.1.4