Enzyme Details

 EC Classification 4.4.1.1
 Enzyme name
(recommended)		 cystathionine gamma-lyase
 Alternative names L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming)
homoserine deaminase
homoserine dehydratase
cystine desulfhydrase
cysteine desulfhydrase
gamma-cystathionase
cystathionase
homoserine deaminase-cystathionase
gamma-CTL
cystalysin
cysteine lyase
L-cystathionine cysteine-lyase (deaminating)
 Classification
Lyases
Carbon-sulfur lyases
Carbon-sulfur lyases
 Catalyses reactions
Oxaloacetate <-> Pyruvate + CO2
L-Aspartate <-> L-Alanine + CO2
H2O + L-Cysteine <-> Pyruvate + NH3 + Hydrogen sulfide
3-Sulfino-L-alanine <-> L-Alanine + SO2
H2O + L-Cystathionine <-> L-Cysteine + NH3 + 2-Oxobutyrate
Cl- + Pyruvate + NH3 <-> H2O + 3-Chloro-L-alanine
H2O + L-Homocysteine <-> NH3 + 2-Oxobutyrate + Hydrogen sulfide
H2O + L-Cystine <-> Pyruvate + NH3 + Thiocysteine
H2O + Selenocystathionine <-> NH3 + 2-Oxobutyrate + Selenocysteine
H2O + Cystathionine <-> Pyruvate + NH3 + L-Homocysteine
H2O + S-(2-Aminoethyl)-L-cysteine <-> Pyruvate + NH3 + Cysteamine
H2O + 3-Chloro-DL-alanine <-> Unknown + Pyruvate + NH3
H2O + S-Methyl-L-cysteine <-> Pyruvate + NH3 + Methanethiol
2 L-Homocysteine <-> Hydrogen sulfide + L-Homolanthionine
L-Cysteine + L-Homocysteine <-> Hydrogen sulfide + L-Cystathionine
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 4.4.1.1



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