Enzyme Details

 EC Classification 4.1.2.47
 Enzyme name
(recommended)		 (S)-hydroxynitrile lyase
 Alternative names oxynitrilase
HbHNL
(S)-cyanohydrin lyase (cyanide forming)
(S)-cyanohydrin producing hydroxynitrile lyase
(S)-oxynitrilase
(S)-HbHNL
(S)-MeHNL
hydroxynitrile lyase
MeHNL
(S)-selective hydroxynitrile lyase
(S)-cyanohydrin carbonyl-lyase (cyanide forming)
 Classification
Lyases
Carbon-carbon lyases
Aldehyde-lyases
 Catalyses reactions
Mandelonitrile <-> Benzaldehyde + Cyanide
Acetone cyanohydrin <-> Acetone + Cyanide
Benzaldehyde + Cyanide <-> (S)-Mandelonitrile
Cyanide + 2-Methylbenzaldehyde <-> (2S)-Hydroxy-(2-methylphenyl)acetonitrile
Cyanide + 3-Methylbenzaldehyde <-> (2S)-Hydroxy-(3-methylphenyl)acetonitrile
Cyanide + 4-Bromobenzaldehyde <-> (2S)-Hydroxy-(4-bromophenyl)acetonitrile
Cyanide + 3-Methoxybenzaldehyde <-> (2S)-Hydroxy-(3-methoxyphenyl)acetonitrile
Cyanide + 2,4-Dimethylbenzaldehyde <-> (2S)-Hydroxy-(2,4-dimethylphenyl)acetonitrile
Cyanide + 3,4-Dichlorobenzaldehyde <-> (2S)-Hydroxy-(3,4-dichlorophenyl)acetonitrile
Cyanide + 3,5-Dichlorobenzaldehyde <-> (2S)-Hydroxy-(3,5-dichlorophenyl)acetonitrile
Cyanide + 2,6-Dichlorobenzaldehyde <-> (2S)-Hydroxy-(2,6-dichlorophenyl)acetonitrile
Cyanide + 3,5-Dimethoxybenzaldehyde <-> (2S)-Hydroxy-(3,5-dimethoxyphenyl)acetonitrile
Cyanide + Piperonal <-> 2-(Benzo[d][1,3]dioxol-6-yl)-2(S)-hydroxyacetonitrile
Cyanide + Terephthalaldehyde <-> (2S)-Hydroxy-(4-formylphenyl)acetonitrile
Cyanide + Isophthaldehyde <-> (2S)-Hydroxy-(3-formylphenyl)acetonitrile
Cyanide + 4-Biphenylcarboxaldehyde <-> (2S)-Hydroxy-(4-biphenyl)acetonitrile
Cyanide + Undecanal <-> (S)-2-Hydroxydodecanenitrile
Cyanide + trans-2-Hexenal <-> (E,2S)-2-Hydroxyhept-3-enenitrile
Cyanide + Heptanal <-> (S)-2-Hydroxyoctanenitrile
Cyanide + 5-Methyl-2-hexanone <-> (2S)-2-Hydroxy-2,5-dimethylhexanenitrile
4-Hydroxymandelonitrile <-> 4-Hydroxybenzaldehyde + Cyanide
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


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