Enzyme Details

 EC Classification 4.1.1.28
 Enzyme name
(recommended)		 aromatic-L-amino-acid decarboxylase
 Alternative names aromatic-L-amino-acid carboxy-lyase
DOPA decarboxylase
tryptophan decarboxylase
hydroxytryptophan decarboxylase
L-DOPA decarboxylase
aromatic amino acid decarboxylase
5-hydroxytryptophan decarboxylase
aromatic-L-amino-acid carboxy-lyase (tryptamine-forming)
 Classification
Lyases
Carbon-carbon lyases
carboxy-lyases
 Catalyses reactions
L-Tryptophan <-> CO2 + Tryptamine
L-Phenylalanine <-> CO2 + 2-Phenylethylamine
L-Tyrosine <-> CO2 + Tyramine
L-Histidine <-> CO2 + Histamine
L-Dopa <-> CO2 + Dopamine
5-Hydroxy-L-tryptophan <-> CO2 + Serotonin
CO2 + 5-Hydroxykynurenamine <-> 5-Hydroxykynurenine
Pyridoxal phosphate + apo-DDC <-> holo-DDC
L-Dopa + holo-DDC <-> Enzyme-ligand complex
D-Dopa + holo-DDC <-> Enzyme-ligand complex
3,4-Dihydroxyphenylacetate + AADC <-> Enzyme-ligand complex
AADC + L-Dopa methyl ester <-> Enzyme-ligand complex
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 4.1.1.28



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