Enzyme Details

 EC Classification 3.7.1.8
 Enzyme name
(recommended)
2,6-dioxo-6-phenylhexa-3-enoate hydrolase
 Alternative names 2,6-dioxo-6-phenylhexa-3-enoate benzoylhydrolase
HOHPDA hydrolase
 Classification
Hydrolases
Acting on carbon-carbon bonds
In ketonic substances
 Catalyses reactions
H2O + 2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoate <-> Benzoate + 2-Hydroxy-2,4-pentadienoate
H2O + 2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate <-> 2-Hydroxy-2,4-pentadienoate + 4-Chlorobenzoate
H2O + 2-Hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate <-> 2-Hydroxy-2,4-pentadienoate + Salicylate
H2O + 2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate <-> 2-Hydroxymuconate + Catechol
H2O + 3,10-diFluoric-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate <-> Benzoate + 3,10-diFluoric-2-hydroxy-2,4-pentadienoate
H2O + 3-Methyl-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate <-> Benzoate + 3-Methyl-2-hydroxy-2,4-pentadienoate
H2O + 2-Hydroxy-6-oxohexa-2,4-dienoate <-> Formate + 2-Hydroxy-2,4-pentadienoate
H2O + 2-Hydroxy-6-oxo-6-methyl-2,4-dienoate <-> Acetate + 2-Hydroxy-2,4-pentadienoate
H2O + 2-Hydroxy-6-oxo-6-ethyl-2,4-dienoate <-> Propanoate + 2-Hydroxy-2,4-pentadienoate
H2O + 2-Hydroxy-6-oxo-6-isopropyl-2,4-dienoate <-> 2-Hydroxy-2,4-pentadienoate + Isobutanoate
H2O + 2-Hydroxy-6-oxo-6-tert-butyl-2,4-dienoate <-> 2-Hydroxy-2,4-pentadienoate + 2-Dimethyl propanoic acid
H2O + 2-Hydroxy-5-methyl-6-oxo-2,4-dienoate <-> Formate + 2-Hydroxy-2,4-hexadienoate
H2O + 2-Hydroxy-3-chloro-6-oxo-6-phenylhexa-2,4-dienoate <-> Benzoate + 2-Hydroxy-3-chloropenta-2,4-dienoate
H2O + 2-Hydroxy-5-chloro-6-oxo-6-phenylhexa-2,4-dienoate <-> Benzoate + 2-Hydroxy-5-chloro-2,4-pentadienoate
H2O + 2-Hydroxy-6-oxo-6-(2'-chlorophenyl)-hexa-2,4-dienoate <-> 2-Hydroxy-2,4-pentadienoate + 2-Chlorobenzoate
H2O + 2-Hydroxy-6-oxo-6-(3'-chlorophenyl)-hexa-2,4-dienoate <-> 2-Hydroxy-2,4-pentadienoate + 3-Chlorobenzoate
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


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