Enzyme Details

 EC Classification 3.5.4.25
 Enzyme name
(recommended)		 GTP cyclohydrolase II
 Alternative names GTP 7,8-8,9-dihydrolase (diphosphate-forming)
guanosine triphosphate cyclohydrolase II
GTP-8-formylhydrolase
 Classification
Hydrolases
Acting on carbon-nitrogen bonds, other than peptide bonds
In cyclic amidines
 Catalyses reactions
3 H2O + GTP <-> Diphosphate + Formate + 2,5-Diamino-6-hydroxy-4-(5'-phosphoribosylamino)-pyrimidine
H2O + GTP <-> Diphosphate + GMP
2 H2O + Formamidopyrimidine nucleoside triphosphate <-> Diphosphate + Formate + 2,5-Diamino-6-hydroxy-4-(5'-phosphoribosylamino)-pyrimidine
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 3.5.4.25



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