Enzyme Details
EC Classification
3.5.1.88
Enzyme name
(recommended)
peptide deformylase
Alternative names
formyl-L-methionyl peptide amidohydrolase
Classification
Hydrolases
Acting on carbon-nitrogen bonds, other than peptide bonds
In linear amides
Catalyses reactions
H2O + N-Formyl-L-methionine <-> L-Methionine + Formate
H2O + Formyl-L-methionyl peptide <-> Formate + Methionyl peptide
H2O + N-Formyl-Met-Leu-p-nitroanilide <-> Formate + Met-Leu-p-nitroanilide
H2O + N-Formyl-Met-Thr-Ala <-> Formate + Met-Thr-Ala
H2O + N-Formyl-Met-Leu <-> Formate + Met-Leu
H2O + N-Acetyl-Met-Leu-p-nitroanilide <-> Acetate + Met-Leu-p-nitroanilide
H2O + N-Trifluoroacetyl-Met-Leu-p-nitroanilide <-> Met-Leu-p-nitroanilide + Trifluoroacetate
H2O + N-Formyl-Nle-Ala-Ser <-> Formate + Nle-Ala-Ser
H2O + N-Formyl-Nva-Ala-Ser <-> Formate + Nva-Ala-Ser
H2O + N-Formyl-Phe-Ala-Ser <-> Formate + Phe-Ala-Ser
H2O + N-Formyl-Nle-Gly-NH2 <-> Formate + Nle-Gly-NH2
H2O + N-Formyl-Nle-Arg-NH2 <-> Formate + Nle-Arg-NH2
H2O + N-Formyl-Nle-Ser-NH2 <-> Formate + Nle-Ser-NH2
H2O + N-Formyl-Nle-Asp-NH2 <-> Formate + Nle-Asp-NH2
H2O + N-Formyl-Nle-Leu-NH2 <-> Formate + Nle-Leu-NH2
H2O + N-Formyl-Met-Ser-Asn-Glu <-> Formate + Met-Ser-Asn-Glu
H2O + N-Formyl-Met-Leu-Phe <-> Formate + Met-Leu-Phe
H2O + N-Formyl-Met-Leu-Glu <-> Formate + Met-Leu-Glu
H2O + N-Formyl-Met-Ala-OCH3 <-> Formate + Met-Ala-OCH3
H2O + N-Formyl-Met-Ala-O- <-> Formate + Met-Ala-O-
H2O + N-Formyl-Nle-NH(CH3) <-> Formate + Nle-NH(CH3)
H2O + N-Formyl-Nle-NH2 <-> Formate + Nle-NH2
H2O + N-Formyl-Nle-Ala-NH2 <-> Formate + Nle-Ala-NH2
H2O + N-Formyl-Met-Ala-Ser <-> Formate + Met-Ala-Ser
External links
Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop
View all entries for EC Class:
3.5.1.88
© HITS gGmbH
