Enzyme Details

 EC Classification 3.5.1.23
 Enzyme name
(recommended)		 ceramidase
 Alternative names acylsphingosine deacylase
N-acylsphingosine amidohydrolase
glycosphingolipid ceramide deacylase
 Classification
Hydrolases
Acting on carbon-nitrogen bonds, other than peptide bonds
In linear amides
 Catalyses reactions
H2O + N-Acylsphingosine <-> Carboxylate + Sphingosine
H2O + N-Acylsphingosine <-> Fatty acid + Sphingosine
H2O + Dihydroceramide <-> Fatty acid + Sphinganine
H2O + Phytoceramide <-> Fatty acid + Phytosphingosine
Dodecanoate + Sphingosine <-> H2O + N-Dodecanoylsphingosine
H2O + N-Stearoyl-D-sphingosine <-> Sphingosine + Stearate
H2O + N-Octanoyl-D-sphingosine <-> Octanoate + Sphingosine
H2O + N-Octanoylsphinganine <-> Octanoate + Sphinganine
H2O + N-Hexanoyl-D-erythro-sphingosine <-> Hexanoate + Sphingosine
H2O + N-Palmitoylsphinganine <-> Palmitate + Sphinganine
H2O + N-Oleoyl-D-sphingosine <-> Oleate + Sphingosine
H2O + N-Acetyl-D-sphingosine <-> Acetate + Sphingosine
H2O + D-Erythro-dodecanoyl-7-nitrobenz-2-oxa-1,3-diazolylceramide <-> Sphingosine + N-[12-(7-Nitrobenzo-2-oxa-1,3-diazolyl)amino]dodecanoic acid
H2O + N-Palmitoylsphingosine <-> Palmitate + Sphingosine
H2O + N-Myristoyl-D-sphingosine <-> Myristic acid + Sphingosine
H2O + N-Eicosanoyl-D-sphingosine <-> Arachidic acid + Sphingosine
H2O + Gondoylsphingosine <-> Sphingosine + Gondoic acid
H2O + N-Lignoceroylsphingosine <-> Sphingosine + Lignoceric acid
H2O + Nervonoylsphingosine <-> Sphingosine + Nervonic acid
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 3.5.1.23



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