Enzyme Details

EC Classification

3.4.22.51

Enzyme name
(recommended)

cruzipain

Alternative names

congopain
cruzain
evansain
trypanopain

Classification

Hydrolases

Acting on peptide bonds (peptide hydrolases)

Cysteine endopeptidases

Catalyses reactions

H2O + 2-Aminobenzoyl-KLRRSKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> 2-Aminobenzoyl-KLR + RSKQ-N-(2,4-dinitrophenyl)ethylenediamine

H2O + 2-Aminobenzoyl-KLRLSKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> 2-Aminobenzoyl-KLR + LSKQ-N-(2,4-dinitrophenyl)ethylenediamine

H2O + 2-Aminobenzoyl-KLRFSKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> 2-Aminobenzoyl-KLR + FSKQ-N-(2,4-dinitrophenyl)ethylenediamine

H2O + Benzyloxycarbonyl-phenylalanine-arginine 4-methylcoumarin-7-ylamide <-> Benzyloxycarbonyl-Phe-Arg + 7-Amino-4-methylcoumarin

H2O + S-Benzyl-CFSKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> S-Benzyl-L-cysteine + FSKQ-N-(2,4-dinitrophenyl)ethylenediamine

H2O + 2-Aminobenzoyl-KLFFSKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> FSKQ-N-(2,4-dinitrophenyl)ethylenediamine + 2-Aminobenzoyl-KLF

H2O + 2-Aminobenzoyl-KLKFSKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> FSKQ-N-(2,4-dinitrophenyl)ethylenediamine + 2-Aminobenzoyl-KLK

H2O + 2-Aminobenzoyl-KLGFSKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> FSKQ-N-(2,4-dinitrophenyl)ethylenediamine + 2-Aminobenzoyl-KLG

H2O + 2-Aminobenzoyl-KFRFSKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> 2-Aminobenzoyl-KFR + FSKQ-N-(2,4-dinitrophenyl)ethylenediamine

H2O + 2-Aminobenzoyl-KARFSKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> FSKQ-N-(2,4-dinitrophenyl)ethylenediamine + 2-Aminobenzoyl-KAR

H2O + 2-Aminobenzoyl-KPRFSKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> 2-Aminobenzoyl-KPR + FSKQ-N-(2,4-dinitrophenyl)ethylenediamine

H2O + 2-Aminobenzoyl-KRRFSKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> 2-Aminobenzoyl-KRR + FSKQ-N-(2,4-dinitrophenyl)ethylenediamine

H2O + 2-Aminobenzoyl-LLRFSKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> 2-Aminobenzoyl-LLR + FSKQ-N-(2,4-dinitrophenyl)ethylenediamine

H2O + 2-Aminobenzoyl-HLRFSKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> 2-Aminobenzoyl-HLR + FSKQ-N-(2,4-dinitrophenyl)ethylenediamine

H2O + 2-Aminobenzoyl-ALRFSKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> 2-Aminobenzoyl-ALR + FSKQ-N-(2,4-dinitrophenyl)ethylenediamine

H2O + 2-Aminobenzoyl-KLRFFKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> 2-Aminobenzoyl-KLR + FFKQ-N-(2,4-dinitrophenyl)ethylenediamine

H2O + 2-Aminobenzoyl-KLRFAKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> 2-Aminobenzoyl-KLR + FAKQ-N-(2,4-dinitrophenyl)ethylenediamine

H2O + 2-Aminobenzoyl-KLRFPKQ-N-(2,4-dinitrophenyl)ethylenediamine <-> 2-Aminobenzoyl-KLR + FPKQ-N-(2,4-dinitrophenyl)ethylenediamine

H2O + 2-Aminobenzoyl-KLRFSRQ-N-(2,4-dinitrophenyl)ethylenediamine <-> 2-Aminobenzoyl-KLR + FSRQ-N-(2,4-dinitrophenyl)ethylenediamine

H2O + 2-Aminobenzoyl-KLRFSPQ-N-(2,4-dinitrophenyl)ethylenediamine <-> 2-Aminobenzoyl-KLR + FSPQ-N-(2,4-dinitrophenyl)ethylenediamine

H2O + Benzoyl-Pro-Phe-Arg-p-nitroanilide <-> 4-Nitroaniline + Benzoyl-Pro-Phe-Arg

H2O + 2-Aminobenzoyl-RKVVNVSTGKAPEA-3-nitrotyrosine <-> TGKAPEA-3-nitrotyrosine + 2-Aminobenzoyl-RKVVNVS

External links

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IntEnz (EBI)
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