Enzyme Details

EC Classification

3.4.22

Enzyme name
(recommended)

Cysteine endopeptidases

Classification

Hydrolases

Acting on peptide bonds (peptide hydrolases)

Cysteine endopeptidases

Catalyses reactions

H2O + Benzyloxycarbonyl-Leu-Arg-7-amino-4-methylcoumarin <-> Benzyloxycarbonyl-Leu-Arg + 7-Amino-4-methylcoumarin

H2O + Benzyloxycarbonyl-phenylalanine-arginine 4-methylcoumarin-7-ylamide <-> Benzyloxycarbonyl-Phe-Arg + 7-Amino-4-methylcoumarin

H2O + Benzoyl-Pro-Phe-Arg-p-nitroanilide <-> 4-Nitroaniline + Benzoyl-Pro-Phe-Arg

H2O + Azocasein <-> Unknown

H2O + Hemoglobin <-> Unknown

H2O + Benzyloxycarbonyl-Val-Arg-7-amino-4-methylcoumarin <-> Benzyloxycarbonyl-Val-Arg + 7-Amino-4-methylcoumarin

H2O + Benzyloxycarbonyl-Leu-Leu-Arg-7-Amino-4-methylcoumarin <-> Benzyloxycarbonyl-Leu-Leu-Arg + 7-Amino-4-methylcoumarin

H2O + Benzyloxycarbonyl-Val-Leu-Arg-7-amino-4-methylcoumarin <-> Benzyloxycarbonyl-Val-Leu-Arg + 7-Amino-4-methylcoumarin

H2O + Benzyloxycarbonyl-Val-Val-Arg-7-amino-4-methylcoumarin <-> Benzyloxycarbonyl-Val-Val-Arg + 7-Amino-4-methylcoumarin

H2O + Benzoyl-Phe-Val-Arg-7-Amino-4-methylcoumarin <-> Benzoyl-Phe-Val-Arg + 7-Amino-4-methylcoumarin

H2O + t-Butyloxycarbonyl-Val-Leu-Lys-7-amino-4-methylcoumarin <-> t-Butyloxycarbonyl-Val-Leu-Lys + 7-Amino-4-methylcoumarin

H2O + 2-Aminobenzoyl-FQQP-3-nitrotyrosine-D <-> QP-3-nitrotyrosine-D + 2-Aminobenzoyl-FQ

H2O + 2-Aminobenzoyl-QQIIFQQPQQ-3-nitrotyrosine-D <-> QPQQ-3-nitrotyrosine-D + 2-Aminobenzoyl-QQIIFQ

H2O + 2-Aminobenzoyl-QIIFQQPQQS-3-nitrotyrosine-PPD <-> QPQQS-3-nitrotyrosine-PPD + 2-Aminobenzoyl-QIIFQ

H2O + 2-Aminobenzoyl-FRQQ-3-nitrotyrosine-D <-> QQ-3-nitrotyrosine-D + 2-Aminobenzoyl-FR

H2O + 2-Aminobenzoyl-QPFRQQ-3-nitrotyrosine-D <-> QQ-3-nitrotyrosine-D + 2-Aminobenzoyl-QPFR

H2O + 2-Aminobenzoyl-QQPFRQQAEL-3-nitrotyrosine-PPD <-> QQAEL-3-nitrotyrosine-PPD + 2-Aminobenzoyl-QQPFR

H2O + 2-Aminobenzoyl-VQQP-3-nitrotyrosine-D <-> QP-3-nitrotyrosine-D + 2-Aminobenzoyl-VQ

H2O + 2-Aminobenzoyl-FPVQQPF-3-nitrotyrosine-D <-> QPF-3-nitrotyrosine-D + 2-Aminobenzoyl-FPVQ

H2O + 2-Aminobenzoyl-LQQP-3-nitrotyrosine-D <-> QP-3-nitrotyrosine-D + 2-Aminobenzoyl-LQ

H2O + 2-Aminobenzoyl-QSYLQQPYPQ-3-nitrotyrosine-PPD <-> QPYPQ-3-nitrotyrosine-PPD + 2-Aminobenzoyl-QSYLQ

H2O + 2-Aminobenzoyl-LQSP-3-nitrotyrosine-D <-> 2-Aminobenzoyl-LQ + SP-3-nitrotyrosine-D

H2O + 2-Aminobenzoyl-SQELQSPQQS-3-nitrotyrosine-PPD <-> SPQQS-3-nitrotyrosine-PPD + 2-Aminobenzoyl-SQELQ

H2O + 2-Aminobenzoyl-QPQQP-3-nitrotyrosine-D <-> QP-3-nitrotyrosine-D + 2-Aminobenzoyl-QPQ

H2O + 2-Aminobenzoyl-SQQP-3-nitrotyrosine-D <-> QP-3-nitrotyrosine-D + 2-Aminobenzoyl-SQ

H2O + Benzyloxycarbonyl-Glu-Arg-7-amino-4-methylcoumarin <-> Benzyloxycarbonyl-Glu-Arg + 7-Amino-4-methylcoumarin

H2O + Benzyloxycarbonyl-Arg-Arg-7-amino-4-methylcoumarin <-> Benzyloxycarbonyl-Arg-Arg + 7-Amino-4-methylcoumarin

H2O + H-Pro-Phe-Arg-7-amino-4-methylcoumarin <-> H-Pro-Phe-Arg + 7-Amino-4-methylcoumarin

H2O + Acetyl-Lys-Glu-Lys-Leu-Arg-7-amino-4-methylcoumarin <-> Acetyl-Lys-Glu-Lys-Leu-Arg + 7-Amino-4-methylcoumarin

H2O + Azoalbumin <-> hydrolyzed Azoalbumin

H2O + Peptide <-> Peptide

H2O + Dabcyl-KTSAVLQSGFRKME-Edans <-> Dabcyl-KTSAVLQ + SGFRKME-Edans

H2O + MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 <-> SGFR-Lys(Dnp)-Lys-NH2 + MCA-AVLQ

Papain-like protease + ORF3 protein <-> ORF3 protein-Papain-like protease complex

ORF3 protein + Pvx <-> ORF3 protein-Pvx complex

H2O + Arg-4-methylcoumaryl-7-amide <-> L-Arginine + 7-Amino-4-methylcoumarin

H2O + LC3B <-> MPSE...QETFG + MKLSV

H2O + GATE-16 <-> L-Phenylalanine + MKWM...ENTFG

H2O + LC3B-GST <-> LC3B + GST

H2O + GATE16-GST <-> GST + GATE16

H2O + GABARAP-GST <-> GST + GABARAP

H2O + Atg8L-GST <-> GST + Atg8L

H2O + Acetyl-YASQETFG-7-amino-4-trifluoromethylcoumarin <-> 7-Amino-4-trifluoro-methylcoumarin + Acetyl-YASQETFG

H2O + Acetyl-Thr-Ser-Ala-Val-Leu-His-7-amino-4-carbamoyl-coumarin <-> 7-Amino-4-carbamoyl-coumarin + Acetyl-Thr-Ser-Ala-Val-Leu-His

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 3.4.22