Enzyme Details

EC Classification

3.4.21.104

Enzyme name
(recommended)

mannan-binding lectin-associated serine protease-2

Alternative names

MASP-2
MASP2
MBP-associated serine protease-2
mannose-binding lectin-associated serine protease-2
p100
mannan-binding lectin-associated serine peptidase 2

Classification

Hydrolases

Acting on peptide bonds (peptide hydrolases)

Serine endopeptidases

Catalyses reactions

H2O + Complement component C2 <-> Complement component C2a + Complement component C2b

H2O + Complement component C4 <-> Complement component C4b + Complement component C4a

H2O + N-Acetyl-Gly-Lys methyl ester <-> Methanol + N-Acetyl-Gly-Lys

H2O + N-Benzoyl-L-arginine ethyl ester <-> Ethanol + N-Benzoyl-L-arginine

H2O + N-Carboxybenzyloxyglycine-L-arginine thiobenzyl ester <-> Benzylthiol + N-Carboxybenzyloxyglycine-L-arginine

H2O + p-Tosyl-L-arginine methyl ester <-> Methanol + p-Tosyl-L-arginine

H2O + N-Carbobenzoxy-L-lysine-p-nitrophenyl ester <-> p-Nitrophenol + N-Carbobenzoxy-L-lysine

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 3.4.21.104